[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100654754":3},{"organization":4,"outcomesModule":7,"designInfo":20,"detailedDescription":28,"studyPopulation":19,"armGroups":29,"interventions":38,"overallOfficials":19,"centralContacts":52,"locations":58,"responsibleParty":75,"collaborators":19,"id":79,"slug":80,"hasResults":81,"nctId":82,"briefTitle":83,"officialTitle":84,"acronym":85,"eligibilityCriteria":86,"healthyVolunteers":87,"sex":88,"minAge":89,"maxAge":90,"enrollmentInfo":91,"targetDuration":19,"studyType":94,"phases":95,"briefSummary":96,"conditions":97,"keywords":100,"overallStatus":105,"whyStopped":19,"lastUpdateSubmitDate":106,"lastUpdatePostDateStruct":107,"startDateStruct":110,"completionDateStruct":112,"leadSponsor":114,"locationsCount":115},{"fullName":5,"class":6},"Inonu University","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":19,"otherOutcomes":19},[9,13,16],{"measure":10,"description":11,"timeFrame":12},"Change in Irisin Level","Irisin levels will be assessed in relation to each exercise condition to determine the change in circulating irisin levels associated with aerobic exercise, anaerobic exercise, and high-intensity interval training (HIIT)","Pre-exercise and immediately post-exercise during each exercise session",{"measure":14,"description":15,"timeFrame":12},"Change in Leptin Level","Leptin levels will be assessed in relation to each exercise condition to determine the change in circulating leptin levels associated with aerobic exercise, anaerobic exercise, and high-intensity interval training (HIIT).",{"measure":17,"description":18,"timeFrame":12},"Change in Ghrelin Level","Ghrelin levels will be assessed in relation to each exercise condition to determine the change in circulating ghrelin levels associated with aerobic exercise, anaerobic exercise, and high-intensity interval training (HIIT).",null,{"allocation":21,"interventionModel":22,"interventionModelDescription":23,"primaryPurpose":24,"observationalModel":19,"timePerspective":19,"maskingInfo":25},"NA","SINGLE_GROUP","All participants will complete three exercise conditions-aerobic exercise, anaerobic exercise, and high-intensity interval training (HIIT)-in separate sessions. Each participant will therefore serve as her own control, allowing within-participant comparisons of irisin, leptin, and ghrelin responses across the three exercise modalities.","BASIC_SCIENCE",{"masking":26,"maskingDescription":27,"whoMasked":19},"NONE","No masking was applied because participants and investigators were aware of the exercise condition performed during each session.","This interventional study is designed to investigate and compare the acute effects of aerobic exercise, anaerobic exercise, and high-intensity interval training (HIIT) on irisin, leptin, and ghrelin levels in sedentary women. A total of 20 sedentary women will participate in the study.\n\nParticipants will complete three different exercise conditions: aerobic exercise, anaerobic exercise, and HIIT. Irisin, leptin, and ghrelin levels will be evaluated in relation to each exercise condition to determine acute exercise-induced hormonal responses. The study will compare changes in these biomarkers across the three exercise modalities to determine whether the hormonal responses differ according to exercise type.\n\nThe study is intended to provide a better understanding of the acute endocrine and metabolic responses to exercise modalities with different physiological demands in sedentary women, with particular emphasis on irisin, leptin, and ghrelin.",[30],{"label":31,"type":32,"description":33,"interventionNames":34},"Multiple Exercise Modalities","EXPERIMENTAL","Participants in this arm will complete three different exercise conditions in separate sessions: aerobic exercise, anaerobic exercise, and high-intensity interval training (HIIT). Irisin, leptin, and ghrelin levels will be assessed in relation to each exercise condition to evaluate and compare acute hormonal responses across the three exercise modalities.",[35,36,37],"Behavioral: Aerobic Exercise","Behavioral: Anaerobic Exercise","Behavioral: High-Intensity Interval Training (HIIT)",[39,44,48],{"type":40,"name":41,"description":42,"armGroupLabels":43,"otherNames":19},"BEHAVIORAL","Aerobic Exercise","Participants will complete an aerobic exercise session as one of the three exercise conditions. Irisin, leptin, and ghrelin levels will be assessed in relation to the exercise session to determine the acute hormonal response to aerobic exercise.",[31],{"type":40,"name":45,"description":46,"armGroupLabels":47,"otherNames":19},"Anaerobic Exercise","Participants will complete an anaerobic exercise session as one of the three exercise conditions. Irisin, leptin, and ghrelin levels will be assessed in relation to the exercise session to determine the acute hormonal response to anaerobic exercise.",[31],{"type":40,"name":49,"description":50,"armGroupLabels":51,"otherNames":19},"High-Intensity Interval Training (HIIT)","Participants will complete a high-intensity interval training (HIIT) session as one of the three exercise conditions. Irisin, leptin, and ghrelin levels will be assessed in relation to the exercise session to determine the acute hormonal response to HIIT.",[31],[53],{"name":54,"role":55,"phone":56,"phoneExt":19,"email":57},"Özgür EKEN, PhD","CONTACT","+905532132795","ozgur.eken@inonu.edu.tr",[59],{"facility":60,"status":19,"city":61,"state":62,"zip":19,"country":63,"countryCode":19,"cosmosGeoPoint":64,"geoPoint":69,"contacts":70},"Exercise Physiology Laboratory, Faculty of Sport Sciences, Karabuk University","Karabük","Karabük Province","Turkey (Türkiye)",{"type":65,"coordinates":66},"Point",[67,68],32.62768,41.20488,{"lat":68,"lon":67},[71],{"name":72,"role":55,"phone":73,"phoneExt":19,"email":74},"musa şahin, PhD","+905549755058","musasahin@karabuk.edu.tr",{"type":76,"investigatorFullName":77,"investigatorTitle":78,"investigatorAffiliation":5,"oldNameTitle":19,"oldOrganization":19},"PRINCIPAL_INVESTIGATOR","Assoc. Prof. Dr. Özgür EKEN","Assoc. Prof.Dr.","100654754","effects-of-different-exercise-types-on-irisin-leptin-and-ghrelin-levels-in-sedentary-women-100654754",false,"NCT07805772","Effects of Different Exercise Types on Irisin, Leptin, and Ghrelin Levels in Sedentary Women","Investigation of the Effects of Different Types of Exercise on Irisin, Leptin, and Ghrelin Levels in Sedentary Women","ILEX","Inclusion Criteria: Female participants Sedentary individuals Voluntary participation in the study Ability and willingness to complete the planned exercise sessions\n\nExclusion Criteria: Inability to participate in the planned exercise sessions Withdrawal of consent or unwillingness to continue participation",true,"FEMALE","18 Years","24 Years",{"count":92,"type":93},20,"ESTIMATED","INTERVENTIONAL",[21],"This interventional study aims to investigate the acute effects of three different exercise modalities-aerobic exercise, anaerobic exercise, and high-intensity interval training (HIIT)-on irisin, leptin, and ghrelin levels in sedentary women. A total of 20 sedentary women will participate in the study. Hormonal responses will be evaluated in relation to the exercise sessions to determine exercise-induced changes in irisin, leptin, and ghrelin and to compare the responses associated with the three exercise modalities.",[98,99],"Exercise Physiology","Metabolic Hormones",[101,102,103,104],"Irisin","Leptin","Ghrelin","Sedentary Women","NOT_YET_RECRUITING","2026-09-01",{"date":108,"type":109},"2026-09-04","ACTUAL",{"date":111,"type":93},"2026-09-05",{"date":113,"type":93},"2026-09-30",{"name":5,"class":6},1]