[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100652257":3},{"organization":4,"armGroups":7,"interventions":24,"overallOfficials":23,"centralContacts":34,"locations":40,"responsibleParty":61,"collaborators":65,"id":67,"slug":68,"hasResults":69,"nctId":70,"briefTitle":71,"officialTitle":72,"acronym":73,"eligibilityCriteria":74,"healthyVolunteers":69,"sex":75,"minAge":76,"maxAge":23,"enrollmentInfo":77,"targetDuration":23,"studyType":80,"phases":81,"briefSummary":83,"conditions":84,"keywords":87,"overallStatus":96,"whyStopped":23,"lastUpdateSubmitDate":97,"lastUpdatePostDateStruct":98,"startDateStruct":101,"completionDateStruct":103,"leadSponsor":105,"locationsCount":106},{"fullName":5,"class":6},"University Medical Centre Ljubljana","OTHER",[8,14,19],{"label":9,"type":10,"description":11,"interventionNames":12},"Outpatient HIIT","EXPERIMENTAL","Anticipated number of patients: 15.\n\nParticipants will complete a structured high-intensity interval training (HIIT) programme performed in an outpatient setting. Intensity and progression are identical to the home-based HIIT arm.",[13],"Behavioral: Outpatient high-intensity interval training (HIIT)",{"label":15,"type":10,"description":16,"interventionNames":17},"Home-based HIIT","Anticipated number of patients: 15.\n\nParticipants will complete a structured high-intensity interval training (HIIT) programme performed independently at home. Intensity and progression are identical to the outpatient HIIT arm.",[18],"Behavioral: Home-based high-intensity interval training (HIIT)",{"label":20,"type":21,"description":22,"interventionNames":23},"Control (usual care)","NO_INTERVENTION","Anticipated number of patients: 15.\n\nParticipants will receive usual care, consisting of general counselling on physical activity performed at home, without a structured or supervised exercise training programme.",null,[25,30],{"type":26,"name":27,"description":28,"armGroupLabels":29,"otherNames":23},"BEHAVIORAL","Outpatient high-intensity interval training (HIIT)","A structured exercise programme performed under direct supervision in an outpatient\u002Fclinical setting on a stationary bicycle or treadmill, consisting of 36 one-hour sessions over 2-4 months (approximately 2-3 sessions per week). Each session will comprise 8 five-minute intervals, each consisting of 2 minutes at 85-95% of the heart rate reached at VO2peak, followed by 3 minutes of active recovery. The interval block will be preceded by a 5-minute active warm-up and followed by a 5-minute active cool-down.\n\nInterval intensity will be individually determined for each patient.",[9],{"type":26,"name":31,"description":32,"armGroupLabels":33,"otherNames":23},"Home-based high-intensity interval training (HIIT)","A structured exercise programme performed independently at home, consisting of 36 one-hour sessions over 2-4 months (approximately 2-3 sessions per week). Each session will comprise 8 five-minute intervals, each consisting of 2 minutes at 85-95% of the heart rate reached at VO2peak, followed by 3 minutes of active recovery. The interval block will be preceded by a 5-minute active warm-up and followed by a 5-minute active cool-down.\n\nInterval intensity will be individually determined for each patient.",[15],[35],{"name":36,"role":37,"phone":38,"phoneExt":23,"email":39},"Kevin Pelicon, MD","CONTACT","+38615228011","kevin.pelicon@kclj.si",[41,52],{"facility":5,"status":23,"city":42,"state":23,"zip":43,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":23},"Ljubljana","1000","Slovenia","SI",{"type":47,"coordinates":48},"Point",[49,50],14.50513,46.05108,{"lat":50,"lon":49},{"facility":53,"status":23,"city":54,"state":23,"zip":55,"country":44,"countryCode":45,"cosmosGeoPoint":56,"geoPoint":60,"contacts":23},"University Medical Centre Maribor","Maribor","2000",{"type":47,"coordinates":57},[58,59],15.64593,46.55583,{"lat":59,"lon":58},{"type":62,"investigatorFullName":63,"investigatorTitle":64,"investigatorAffiliation":5,"oldNameTitle":23,"oldOrganization":23},"PRINCIPAL_INVESTIGATOR","Kevin Pelicon","MD",[66],{"name":53,"class":6},"100652257","effects-of-exercise-in-patients-with-repaired-coarctation-of-the-aorta-100652257",false,"NCT07771023","Effects of Exercise in Patients With Repaired Coarctation of the Aorta","Effects of Exercise on Select Indicators of Cardiovascular Health in Patients With Repaired Coarctation of the Aorta","KOREKT","Inclusion Criteria:\n\n* surgically repaired coarctation of the aorta,\n* age at least 18 years, and\n* signed informed consent form.\n\nExclusion Criteria:\n\n* residual aortic stenosis (gradient across the narrowing \\>20 mmHg),\n* presence of ascending aortic aneurysm,\n* recent major cardiovascular event or other event requiring hospitalization (event less than 2 months before inclusion),\n* unstable rhythm disturbances,\n* unstable or low-threshold angina pectoris,\n* NYHA class III or IV heart failure, and\n* pregnancy.","ALL","18 Years",{"count":78,"type":79},45,"ESTIMATED","INTERVENTIONAL",[82],"NA","This interventional study will investigate the effects of high-intensity interval training (HIIT) in adults with repaired coarctation of the aorta. Participants will be randomised into three groups: HIIT performed at home, HIIT performed in a supervised outpatient setting, or a control group receiving usual care. The two HIIT protocols will be identical in intensity and progression, individually prescribed for each patient.\n\nThe study will evaluate the effects of HIIT on exercise capacity, health-related quality of life, blood pressure response to exercise, and other select measures of cardiovascular health, including vascular stiffness and endothelial function. In addition, the study will examine the acute effects of a single exercise session on arterial stiffness.",[85,86],"Coarctation of the Aorta","Coarctation of Aorta",[88,89,90,91,92,93,94,95],"exercise","HIIT","home-based exercise","exercise training","cardiopulmonary exercise testing","arterial stiffness","hypertensive reaction","congenital heart disease","NOT_YET_RECRUITING","2026-08-13",{"date":99,"type":100},"2026-08-18","ACTUAL",{"date":102,"type":79},"2026-08",{"date":104,"type":79},"2027-10",{"name":5,"class":6},2]