[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100650386":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":21,"centralContacts":25,"locations":31,"responsibleParty":45,"collaborators":20,"id":47,"slug":48,"hasResults":49,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":20,"eligibilityCriteria":53,"healthyVolunteers":49,"sex":54,"minAge":55,"maxAge":56,"enrollmentInfo":57,"targetDuration":20,"studyType":60,"phases":61,"briefSummary":63,"conditions":64,"keywords":67,"overallStatus":69,"whyStopped":20,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":79},{"fullName":5,"class":6},"Yale University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Radical prostatectomy + High-Intensity Interval Training (HIIT)","EXPERIMENTAL","Participants who undergo radical prostatectomy will perform HIIT exercise regimen for a minimum of four weeks prior to prostatectomy under the supervision of a physical therapist or exercise physiologist.",[13],"Behavioral: High-intensity interval training (HIIT) exercise",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"BEHAVIORAL","High-intensity interval training (HIIT) exercise","The intervention will consist of vigorous physical activity for a goal of 60 minutes each week for a minimum of four weeks prior to prostatectomy.",[9],null,[22],{"name":23,"affiliation":5,"role":24},"Michael Leapman, MD","PRINCIPAL_INVESTIGATOR",[26],{"name":27,"role":28,"phone":29,"phoneExt":20,"email":30},"Sarah Linsky, MPH","CONTACT","475-375-6129","sarah.linsky@yale.edu",[32],{"facility":33,"status":20,"city":34,"state":35,"zip":36,"country":37,"countryCode":38,"cosmosGeoPoint":39,"geoPoint":44,"contacts":20},"Yale New Haven Hospital","New Haven","Connecticut","06520","United States","US",{"type":40,"coordinates":41},"Point",[42,43],-72.92816,41.30815,{"lat":43,"lon":42},{"type":46,"investigatorFullName":20,"investigatorTitle":20,"investigatorAffiliation":20,"oldNameTitle":20,"oldOrganization":20},"SPONSOR","100650386","effects-of-exercise-prior-to-radical-prostatectomy-100650386",false,"NCT07746414","Effects of Exercise Prior to Radical Prostatectomy","Effects of High Intensity Interval Training Among Patients With Prostate Cancer Prior to Radical Prostatectomy","Inclusion Criteria:\n\n* Scheduled or intended treatment with radical prostatectomy at Yale New Haven Hospital\n* English language fluency\n* Clinically localized low, intermediate or high risk by National Comprehensive Cancer Network (NCCN) criteria\n* Able to attend 2 in person exercise training sessions per week for four-six weeks\n\nExclusion Criteria:\n\n* Treatment with non-surgical modality\n* Prior therapy for prostate cancer (e.g. radiation therapy or focal therapy)\n* Already engaged in regular exercise (\\>60 minutes per week)\n* Unstable cardiovascular disease\n* Physical mobility limitation, unable to walk or exercise\n* Locally advanced (cT4 or cN1 or cM1) prostate cancer\n* Prior treatment with androgen deprivation therapy","ALL","35 Years","80 Years",{"count":58,"type":59},20,"ESTIMATED","INTERVENTIONAL",[62],"NA","This pilot study will explore the metabolic and psychological effects of High-Intensity Interval Training (HIIT) exercise as well as its impact on patient recovery from radical prostatectomy.",[65,66],"Recovery","Post Prostatectomy",[68],"High-Intensity Interval Training (HIIT)","NOT_YET_RECRUITING","2026-08-04",{"date":72,"type":73},"2026-08-07","ACTUAL",{"date":75,"type":59},"2026-08",{"date":77,"type":59},"2027-08",{"name":5,"class":6},1]