[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100651364":3},{"organization":4,"armGroups":7,"interventions":24,"overallOfficials":33,"centralContacts":37,"locations":43,"responsibleParty":58,"collaborators":12,"id":60,"slug":61,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":64,"acronym":12,"eligibilityCriteria":65,"healthyVolunteers":62,"sex":66,"minAge":67,"maxAge":68,"enrollmentInfo":69,"targetDuration":12,"studyType":72,"phases":73,"briefSummary":75,"conditions":76,"keywords":78,"overallStatus":85,"whyStopped":12,"lastUpdateSubmitDate":86,"lastUpdatePostDateStruct":87,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":95},{"fullName":5,"class":6},"University of Macau","OTHER",[8,13,19],{"label":9,"type":10,"description":11,"interventionNames":12},"Arm 1","NO_INTERVENTION","Participants maintain their usual daily activities without additional prescribed exercise. Daily physical activity will be recorded throughout the intervention period.",null,{"label":14,"type":15,"description":16,"interventionNames":17},"Arm 2（Exercise Snacks）","EXPERIMENTAL","Twice-daily short-bout exercise snacks. Each session includes 5 sets of 6-second high-knee exercise with 9 seconds rest between sets.",[18],"Behavioral: Exercise Snacks",{"label":20,"type":15,"description":21,"interventionNames":22},"Arm 3（High-Intensity Interval Training ）","One intervention session scheduled in the afternoon. The protocol consists of 10 sets of 6-second high-knee exercise, separated by 9 seconds of rest between sets.",[23],"Behavioral: High-Intensity Interval Training",[25,30],{"type":26,"name":27,"description":28,"armGroupLabels":29,"otherNames":12},"BEHAVIORAL","High-Intensity Interval Training","Acute high-intensity interval training protocol: 10 × 6 s high-knee exercise with 9 s rest between sets, completed in a single afternoon session.",[20],{"type":26,"name":31,"description":16,"armGroupLabels":32,"otherNames":12},"Exercise Snacks",[14],[34],{"name":35,"affiliation":5,"role":36},"Zhaowei Kong, PhD","PRINCIPAL_INVESTIGATOR",[38],{"name":39,"role":40,"phone":41,"phoneExt":12,"email":42},"Yuping Zhou, master","CONTACT","+86-18811611796","yc57146@um.edu.mo",[44],{"facility":45,"status":12,"city":46,"state":47,"zip":12,"country":48,"countryCode":49,"cosmosGeoPoint":50,"geoPoint":55,"contacts":56},"Hangzhou First Social Welfare Institute","Hangzhou","Zhejiang","China","CN",{"type":51,"coordinates":52},"Point",[53,54],120.16142,30.29365,{"lat":54,"lon":53},[57],{"name":39,"role":40,"phone":41,"phoneExt":12,"email":42},{"type":59,"investigatorFullName":12,"investigatorTitle":12,"investigatorAffiliation":12,"oldNameTitle":12,"oldOrganization":12},"SPONSOR","100651364","effects-of-exercise-snacks-on-physical-health-and-cognitive-function-in-individuals-with-intellectual-disabilities-100651364",false,"NCT07759232","Effects of Exercise Snacks on Physical Health and Cognitive Function in Individuals With Intellectual Disabilities","Inclusion Criteria:\n\n1. Aged 18-35 years old;\n2. Clinically diagnosed mild to moderate intellectual disability;\n3. Able to follow simple verbal instructions and complete exercise protocols;\n4. No contraindications for moderate physical activity confirmed by medical inquiry;\n5. Participants or legal guardians provide written informed consent;\n6. Maintain stable daily routine and do not participate in other structured exercise programs during the trial.\n\nExclusion Criteria:\n\n1. Severe physical disabilities, orthopedic injury or neurological disorders that restrict movement;\n2. History of cardiovascular disease, uncontrolled hypertension or other exercise contraindications;\n3. Current psychiatric medication that significantly affects motor or cognitive function;\n4. Inability to cooperate with EEG and physiological signal collection;\n5. Pregnancy;\n6. Participation in other interventional studies within the past 3 months.","ALL","18 Years","35 Years",{"count":70,"type":71},24,"ESTIMATED","INTERVENTIONAL",[74],"NA","Intellectual disability (ID) is a neurodevelopmental disorder accompanied by sedentary lifestyles, which worsens cognitive function and physical health. Short-duration high-frequency exercise snacks (ES) may be a feasible intervention for adults with ID. This randomized controlled crossover study aims to explore the acute effects of exercise snacks, conventional HIIT and daily routine control on cognitive function, stereotyped behaviors and prefrontal cortex activation in adults with mild to moderate ID. All participants will receive three intervention conditions with a 1-week washout period between each trial. Neurophysiological indicators including EEG and heart rate variability will be measured to reveal the underlying mechanisms.",[77],"Intellectual Disability",[31,79,80,81,82,83,84],"High-intensity Interval Training","Cognitive Function","Physical Activity","Prefrontal Cortex","Neurodevelopmental disorders","intellectual disability","NOT_YET_RECRUITING","2026-08-06",{"date":88,"type":89},"2026-08-12","ACTUAL",{"date":91,"type":71},"2026-11-16",{"date":93,"type":71},"2027-02-08",{"name":5,"class":6},1]