[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100534307":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":29,"centralContacts":37,"locations":43,"responsibleParty":66,"collaborators":68,"id":72,"slug":73,"hasResults":74,"nctId":75,"briefTitle":76,"officialTitle":77,"acronym":78,"eligibilityCriteria":79,"healthyVolunteers":80,"sex":81,"minAge":82,"maxAge":83,"enrollmentInfo":84,"targetDuration":25,"studyType":87,"phases":88,"briefSummary":90,"conditions":91,"keywords":93,"overallStatus":46,"whyStopped":25,"lastUpdateSubmitDate":102,"lastUpdatePostDateStruct":103,"startDateStruct":106,"completionDateStruct":108,"leadSponsor":110,"locationsCount":111},{"fullName":5,"class":6},"University of California, Davis","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Goji berry","EXPERIMENTAL","For the goji berry arm, participants will consume goji berries.",[13],"Dietary Supplement: Goji berry",{"label":15,"type":16,"description":17,"interventionNames":18},"Fiber","ACTIVE_COMPARATOR","For the fiber arm, participants will consume fiber supplements that closely matches the fiber type and amount found in the portion of goji berries.",[19],"Dietary Supplement: Fiber",[21,26],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"DIETARY_SUPPLEMENT","Participants will be instructed to consume 14 grams of goji berries 5 days a week for 6 months",[9],null,{"type":22,"name":15,"description":27,"armGroupLabels":28,"otherNames":25},"Participants will be instructed to consume the fiber supplements 5 days a week for 6 months",[15],[30,33,35],{"name":31,"affiliation":5,"role":32},"Robert M Hackman, PhD","PRINCIPAL_INVESTIGATOR",{"name":34,"affiliation":5,"role":32},"Angela M Zivkovic, PhD",{"name":36,"affiliation":5,"role":32},"Glenn Yiu, MD, PhD",[38],{"name":39,"role":40,"phone":41,"phoneExt":25,"email":42},"Denise Macias, CCRP","CONTACT","(916) 734-6303","dcmacias@ucdavis.edu",[44],{"facility":45,"status":46,"city":47,"state":48,"zip":49,"country":50,"countryCode":51,"cosmosGeoPoint":52,"geoPoint":57,"contacts":58},"UC Davis Eye Center, Tschannen Eye Institute","RECRUITING","Sacramento","California","95817","United States","US",{"type":53,"coordinates":54},"Point",[55,56],-121.4944,38.58157,{"lat":56,"lon":55},[59,62],{"name":60,"role":40,"phone":61,"phoneExt":25,"email":42},"Denise C Macias","916-734-6303",{"name":63,"role":40,"phone":64,"phoneExt":25,"email":65},"Susan M Garcia","916-734-4546","smgarcia@ucdavis.edu",{"type":67,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR",[69],{"name":70,"class":71},"United States Department of Agriculture (USDA)","FED","100534307","effects-of-goji-vs-fiber-on-macular-degeneration-100534307",false,"NCT06237127","Effects of Goji vs. Fiber on Macular Degeneration","Effects of Goji Berry Intake on Risk of Age-related Macular Degeneration: A Randomized Clinical Trial","GOJI","Inclusion Criteria:\n\n* Family history of AMD\n* Hyperlipidemia or managed diabetes\n* 65 - 95 years of age\n\nExclusion Criteria:\n\n* Dislike of, or allergy to, goji berries or any of the ingredients in the fiber-rich wafers and gummies (wheat, corn, oats, soy, natural orange flavor, xylitol, annatto, pectin, or other food ingredients)\n* Consumption of \\> 2 alcoholic drinks per day\n* Indications of substance or alcohol abuse\n* Current or planned use of a blood thinner (e.g., Coumadin, Warfarin) at any time during study\n* Use of multi-vitamin or any other supplements that contain lutein and\u002For zeaxanthin (if willing to stop the supplement, subject can be enrolled 6 months from stop date)\n* Taking any new medications started within the past 6 months, or changes in medication regimen planned in the next 6 months (stable use greater than 6 months is not exclusionary)\n* Any planned international travel during the study\n* Consuming \\>3 servings\u002Fday of a combination of spinach, kale, lettuce, orange bell peppers, corn, parsley, squash, broccoli, pumpkin, edamame\n* Regularly consuming \\>3 eggs\u002Fday\n* Currently participating in any other interventional research study\n* Diagnosed with inflammatory bowel disease, irritable bowel syndrome, other gastrointestinal disorder, undergoing cancer therapy or immunocompromised, or diagnosis of another condition where lutein, zeaxanthin and\u002For fiber supplementation would be contraindicated or would interfere with ability to participate in the study\n* Any physical characteristic or condition that precludes ability to perform study procedures\n* Medical or psychiatric condition that, in the opinion of the Investigator, would compromise study findings or prevent the participant from completing the study",true,"ALL","65 Years","95 Years",{"count":85,"type":86},60,"ESTIMATED","INTERVENTIONAL",[89],"NA","The goal of this project is to conduct a clinical trial in 60 participants ranging from age 65-95 who are at risk for age-related macular degeneration (AMD). The study will evaluate the effects of 14g of goji berry intake or an equivalent amount and type of fiber, five days a week for six months, on visual health, gut microbiome profiles, skin carotenoid measures, and lipoprotein profiles.",[92],"Age-Related Macular Degeneration",[94,92,95,96,15,97,98,99,100,101],"Goji Berry","Lutein","Zeaxanthin","Carotenoids","Gut Microbiome","HDL","Cholesterol Efflux Capacity","Eye Health","2026-07-15",{"date":104,"type":105},"2026-07-17","ACTUAL",{"date":107,"type":105},"2024-04-29",{"date":109,"type":86},"2027-12-31",{"name":5,"class":6},1]