[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100652418":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":24,"centralContacts":28,"locations":34,"responsibleParty":48,"collaborators":24,"id":52,"slug":53,"hasResults":54,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":58,"eligibilityCriteria":59,"healthyVolunteers":54,"sex":60,"minAge":61,"maxAge":62,"enrollmentInfo":63,"targetDuration":24,"studyType":66,"phases":67,"briefSummary":69,"conditions":70,"keywords":73,"overallStatus":77,"whyStopped":24,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":87},{"fullName":5,"class":6},"Shanghai Jiao Tong University School of Medicine","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Individualized dietary intervention","EXPERIMENTAL","Individualized dietary intervention guided by refined obesity phenotyping and based on digital management tools was adopted. Dietitians will use the decision tree algorithm of the digital management tool to first set the macronutrient ratios and dietary pattern recommendations based on ①metabolic health status and ②body composition characteristics, then set the eating rhythm recommendations based on ③emotional characteristics and ④individual behavioral characteristics，and then set the food recommendations based on ⑤dietary preferences.",[13],"Behavioral: Individualized dietary intervention",{"label":15,"type":10,"description":16,"interventionNames":17},"Traditional energy-restricted balanced diet","A traditional energy-restricted balanced diet based on the resting energy expenditure measured at baseline for each participant. A daily caloric deficit of 500 kcal was set for each individual. Dietitians provided dietary guidance plans and recommended sample menus in accordance with the traditional general dietary recommendations from the \"Dietary Reference Intakes for Chinese Residents.\" The overall dietary principles emphasized a diet rich in whole grains, low in fat, with ample vegetables and fruits, and avoiding added sugars.",[18],"Behavioral: Traditional energy-restricted balanced diet",[20,25],{"type":21,"name":9,"description":22,"armGroupLabels":23,"otherNames":24},"BEHAVIORAL","The participants will take a individualized dietary intervention guided by refined obesity phenotyping and based on digital management tools. Dietitians will use the decision tree algorithm of the digital management tool to first set the macronutrient ratios and dietary pattern recommendations based on ①metabolic health status and ②body composition characteristics, then set the eating rhythm recommendations based on ③emotional characteristics and ④individual behavioral characteristics，and then set the food recommendations based on ⑤dietary preferences.",[9],null,{"type":21,"name":15,"description":26,"armGroupLabels":27,"otherNames":24},"The participants will take a traditional energy-restricted balanced diet based on the resting energy expenditure measured at baseline for each participant. A daily caloric deficit of 500 kcal was set for each individual. Dietitians provided dietary guidance plans and recommended sample menus in accordance with the traditional general dietary recommendations from the \"Dietary Reference Intakes for Chinese Residents.\" The overall dietary principles emphasized a diet rich in whole grains, low in fat, with ample vegetables and fruits, and avoiding added sugars.",[15],[29],{"name":30,"role":31,"phone":32,"phoneExt":24,"email":33},"Jieli Lu, MD, PhD","CONTACT","+86-15921591766","jielilu@hotmail.com",[35],{"facility":36,"status":24,"city":37,"state":38,"zip":39,"country":40,"countryCode":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":24},"Ruijin hospital, Shanghai Jiaotong University School of Medicine","Shanghai","Shanghai Municipality","200025","China","CN",{"type":43,"coordinates":44},"Point",[45,46],121.45806,31.22222,{"lat":46,"lon":45},{"type":49,"investigatorFullName":50,"investigatorTitle":51,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"SPONSOR_INVESTIGATOR","Guang Ning","Prof","100652418","efficacy-of-different-dietary-pattern-in-long-term-weight-management-100652418",false,"NCT07773558","Efficacy of Different Dietary Pattern in Long-term Weight Management","A Multicenter Randomized Controlled Trial Evaluating the Efficacy of Different Dietary Pattern Management Programs in Long-term Weight Management","EDI-Weight","Inclusion Criteria:\n\n1. Male or female, aged 20-59 years\n2. Obesity defined by BMI≥28 kg\u002Fm²;\n3. With willingness to undergo dietary intervention for weight loss.\n\nExclusion Criteria:\n\n1. BMI≥40 kg\u002Fm²;\n2. Suffering from gastrointestinal diseases that affect food digestion and absorption (such as functional bowel disorders, etc.), or having a known history of food allergies, or having a history of previous gastrointestinal surgery that affects dietary intervention;\n3. Suffering from diseases that affect body weight or glucose and lipid metabolism (such as uncontrolled hyponatremia, thyroid dysfunction, secondary hypertension, type 1 diabetes, Cushing's syndrome, etc.);\n4. Currently undergoing pharmacological treatment that affects body weight or glucose and lipid metabolism (such as thyroid medications, corticosteroids, antidiabetic drugs, lipid-lowering drugs, diuretics, etc.);\n5. Having been diagnosed with clinical cardiovascular disease (coronary heart disease, stroke, heart failure, etc.) or malignancy;\n6. Suffering from severe liver or kidney disease (alanine aminotransferase or serum creatinine levels exceeding 2 times the upper limit of normal);\n7. Pregnant, breastfeeding, or women of childbearing potential who are not using contraception;\n8. Any condition deemed by the investigator to affect study compliance;\n9. Currently participating in another interventional study or having participated in another drug clinical trial within the past 3 months.","ALL","20 Years","59 Years",{"count":64,"type":65},800,"ESTIMATED","INTERVENTIONAL",[68],"NA","This study is a nationwide multi-center, long-term randomized controlled clinical trial, aiming to evaluate the effects of individualized dietary pattern management programs compared to traditional energy-restricted diets in weight management.",[71,72],"Obesity and Overweight","Dietary Intervention",[74,75,76],"dietary","weight","obesity","NOT_YET_RECRUITING","2026-08-14",{"date":80,"type":81},"2026-08-19","ACTUAL",{"date":83,"type":65},"2026-09-01",{"date":85,"type":65},"2029-06-01",{"name":50,"class":6},1]