[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100652832":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":18,"centralContacts":27,"locations":37,"responsibleParty":54,"collaborators":18,"id":58,"slug":59,"hasResults":60,"nctId":61,"briefTitle":62,"officialTitle":63,"acronym":18,"eligibilityCriteria":64,"healthyVolunteers":60,"sex":65,"minAge":66,"maxAge":18,"enrollmentInfo":67,"targetDuration":18,"studyType":70,"phases":71,"briefSummary":73,"conditions":74,"keywords":78,"overallStatus":81,"whyStopped":18,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":91},{"fullName":5,"class":6},"Thammasat University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"ONS group","EXPERIMENTAL","Receive oral nutritional supplement (Ensure® Plus Advance) 2 serves \u002F day x 30 days + Standard oral intake",[13],"Dietary Supplement: Oral nutritional supplementation",{"label":15,"type":16,"description":17,"interventionNames":18},"Control group","NO_INTERVENTION","Receive standard oral intake",null,[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DIETARY_SUPPLEMENT","Oral nutritional supplementation","Oral nutritional supplement that consists of 20 grams of protein, 1.5 grams of calcium β-hydroxy-β-methylbutyrate (CaHMB), 0.5 gram of calcium, 500 international units (IU) of vitamin D and calories of 330 kcal per one bottle of 220 ml (Ensure® Advance Plus, Abbott Laboratorios S.A.)",[9],[26],"Ensure Advanced Plus",[28,33],{"name":29,"role":30,"phone":31,"phoneExt":18,"email":32},"Natthasit Wongwarawanith, MD","CONTACT","+66868855682","natthasit_fight@hotmail.com",{"name":34,"role":30,"phone":35,"phoneExt":18,"email":36},"Supakit Kanitnate, MD","+66899853635","naypeng@hotmail.com",[38],{"facility":5,"status":18,"city":39,"state":18,"zip":40,"country":41,"countryCode":42,"cosmosGeoPoint":43,"geoPoint":48,"contacts":49},"Pathum Thani","12120","Thailand","TH",{"type":44,"coordinates":45},"Point",[46,47],100.53049,14.01346,{"lat":47,"lon":46},[50],{"name":51,"role":30,"phone":52,"phoneExt":18,"email":53},"Department of Orthopaedics, Thammasat University","+669269775","orthotunited@orthothamma.com",{"type":55,"investigatorFullName":56,"investigatorTitle":57,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"PRINCIPAL_INVESTIGATOR","Natthasit Wongwarawanith","Principal Investigator","100652832","efficacy-of-oral-nutritional-supplement-in-femoral-neck-fracture-patients-undergoing-hip-arthroplasty-100652832",false,"NCT07780006","Efficacy of Oral Nutritional Supplement in Femoral Neck Fracture Patients Undergoing Hip Arthroplasty","Efficacy of Oral Nutritional Supplement in Femoral Neck Fracture Patients Undergoing Hip Arthroplasty: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Femoral neck fracture patients undergoing hip arthroplasty (Total hip arthroplasty or bipolar hemiarthroplasty)\n* Age ≥ 65 years\n* American Society of Anesthesiologists (ASA) class I-III\n* Participants understand and consent to the protocol of the trial\n\nExclusion Criteria:\n\n* Pathologic fracture or high impact fracture\n* Morbid obesity (Body mass index \\> 40)\n* Chronic kidney disease (Chronic kidney disease stage \\> 3b or estimated glomerular filtration rate (eGFR) \\\u003C 30)\n* Thyroid disease or endrocrinopathy\n* Gastrointestinal intolerance preventing oral supplementation or Malabsorption syndromes\n* Malignancy with radiotherapy or chemotherapy\n* Cognitive disorder\n* Decompensated Liver Disease or Cirrhosis Child-Pugh Class B-C\n* Known allergy\u002Fintolerance to milk or other supplement ingredients","ALL","65 Years",{"count":68,"type":69},60,"ESTIMATED","INTERVENTIONAL",[72],"NA","This study aim to compare the efficacy of oral nutritional supplementation (ONS) in femoral neck fracture patients undergoing hip arthroplasty compared with placebo. The hypothesis is \"Oral nutritional supplement with Beta-hydroxy-beta-methylbutyrate (HMB) can improve muscle strength in femoral neck fracture patients undergoing hip arthroplasty\".\n\nFemoral neck fracture patients aged more than 65 years will be enrolled and allocated into 2 groups\n\n* ONS group: Oral nutritional supplement (Ensure® Plus Advance) 2 serves \u002F day x 30 days + Standard oral intake\n* Control group: Standard oral intake\n\nPrimary outcome is Grip strength, assessed using hand dynamometer on admission and 2, 6, 12 weeks postoperatively.\n\nSecondary outcomes are\n\n* Serum albumin assessed on admission and 2, 6, 12 weeks postoperatively\n* Barthel index assessed at 2, 6, 12 weeks postoperatively\n* Mini Nutritional Assessment (MNA), Geriatric Nutritional Risk Index (GNRI) assessed at 2, 6, 12 weeks postoperatively\n* Length of stay (day)\n* Time up and go (TUG), assessed at 2, 6, 12 weeks postoperatively\n* Oxford hip score (OHS), assessed at 2, 6, 12 weeks postoperatively\n* Complications, rate of readmission, mortality rate assessed until 3 months",[75,76,77],"Femoral Neck Fractures","Geriatric Hip Fracture","Hip Fracture, Post Surgery Recovery, Muscle Resilience",[79,22,80],"Femoral neck fractures","HMB","NOT_YET_RECRUITING","2026-08-18",{"date":84,"type":85},"2026-08-21","ACTUAL",{"date":87,"type":69},"2026-10",{"date":89,"type":69},"2027-12",{"name":5,"class":6},1]