[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100655592":3},{"organization":4,"outcomesModule":7,"designInfo":14,"detailedDescription":13,"studyPopulation":13,"armGroups":20,"interventions":32,"overallOfficials":13,"centralContacts":13,"locations":13,"responsibleParty":41,"collaborators":13,"id":45,"slug":46,"hasResults":47,"nctId":48,"briefTitle":49,"officialTitle":49,"acronym":13,"eligibilityCriteria":50,"healthyVolunteers":47,"sex":51,"minAge":52,"maxAge":53,"enrollmentInfo":54,"targetDuration":13,"studyType":57,"phases":58,"briefSummary":60,"conditions":61,"keywords":13,"overallStatus":63,"whyStopped":13,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":13},{"fullName":5,"class":6},"Assiut University","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":13},[9],{"measure":10,"description":11,"timeFrame":12},"Total opioid consumption","Total opioid consumption (IV NALUFIN) during the first 24 postoperative hours","24 hours",null,{"allocation":15,"interventionModel":16,"interventionModelDescription":13,"primaryPurpose":17,"observationalModel":13,"timePerspective":13,"maskingInfo":18},"RANDOMIZED","PARALLEL","TREATMENT",{"masking":19,"maskingDescription":13,"whoMasked":13},"NONE",[21,27],{"label":22,"type":23,"description":24,"interventionNames":25},"Group I","ACTIVE_COMPARATOR","External Oblique Intercostal Block, EOI",[26],"Procedure: External Oblique Intercostal Block",{"label":28,"type":23,"description":29,"interventionNames":30},"Group II","Port-Site Local Anesthetic Infiltration",[31],"Procedure: Port-Site Local Anesthetic Infiltration",[33,37],{"type":34,"name":29,"description":35,"armGroupLabels":36,"otherNames":13},"PROCEDURE","patients undergoing laparoscopic sleeve gastrectomy receiving port-site infiltration with 5 ml 0.25% bupivacaine at each port site.",[28],{"type":34,"name":38,"description":39,"armGroupLabels":40,"otherNames":13},"External Oblique Intercostal Block","ultrasound-guided external oblique intercostal block with 30 ml 0.25% bupivacaine bilaterally.",[22],{"type":42,"investigatorFullName":43,"investigatorTitle":44,"investigatorAffiliation":5,"oldNameTitle":13,"oldOrganization":13},"PRINCIPAL_INVESTIGATOR","Hazem Samir Mohamed Ahmed","Resident doctor at Anesthesia, Intensive Care and Pain Management","100655592","efficacy-of-ultrasound-guided-external-oblique-intercostal-plane-block-versus-port-site-local-anesthetic-infiltration-for-postoperative-analgesia-and-pulmonary-function-after-laparoscopic-sleeve-gastrectomy-100655592",false,"NCT07816055","Efficacy of Ultrasound-guided External Oblique Intercostal Plane Block Versus Port-site Local Anesthetic Infiltration for Postoperative Analgesia and Pulmonary Function After Laparoscopic Sleeve Gastrectomy","Inclusion Criteria:\n\n* • Age 18-65 years\n\n  * BMI between 35 kg\u002Fm2 and 40 kg\u002Fm²\n  * ASA (I-II-III)\n  * Elective laparoscopic sleeve gastrectomy\n  * Ability to provide informed consent\n\nExclusion Criteria:\n\n* • Patient refusal\n\n  * Allergy to local anesthetics\n  * Coagulopathy\n  * Infection at injection site\n  * Chronic opioid use\n  * Hepatic failure\n  * Renal failure\n  * Conversion to open surgery\n  * OSAS-home CPAP\n  * Cardiac patients\n  * Super morbid \\>50 kg \u002F m²","ALL","18 Years","65 Years",{"count":55,"type":56},54,"ESTIMATED","INTERVENTIONAL",[59],"NA","Obesity poses severe global health risks and induces complex cardiorespiratory alterations, making perioperative care critical. For patients with morbid obesity, Laparoscopic Sleeve Gastrectomy (LSG) is the most effective long-term treatment. However, despite being minimally invasive, LSG causes significant early postoperative pain from trocar insertion, pneumo-peritoneum, and visceral trauma. Uncontrolled pain can lead to impaired respiratory function, delayed recovery, and increased opioid-related side effects. Enhanced Recovery After Surgery (ERAS) protocols emphasize opioid-sparing multimodal analgesia. While local port-site infiltration is inexpensive and simple, its effects are localized and short-lived, often requiring supplemental opioids. In contrast, the ultrasound-guided External Oblique Intercostal (EOI) block targets the fascial plane between the external oblique and intercostal muscles (T6-T10). It provides superficial, easily identifiable landmarks in obese patients and delivers widespread sensory blockade across the upper anterior abdominal wall. To evaluate superior pain management strategies, a prospective, randomized, controlled study compares the analgesic efficacy of ultrasound-guided bilateral EOI block versus conventional port-site local anesthetic infiltration in patients undergoing elective LSG. Key Study Metrics (First 24 Postoperative Hours) Primary Outcomes: Total postoperative opioid consumption and pain scores. Secondary Outcomes: Time to first rescue analgesia, incidence of postoperative nausea and vomiting (PONV), overall patient satisfaction, and recovery metrics. Ultimately, demonstrating the superior efficacy of the EOI block over port-site infiltration may refine perioperative analgesic protocols, reduce opioid dependence, and improve recovery outcomes in bariatric surgery.",[62],"Laparoscopic Sleeve Gastrectomy","NOT_YET_RECRUITING","2026-09-07",{"date":66,"type":67},"2026-09-11","ACTUAL",{"date":69,"type":56},"2026-10",{"date":71,"type":56},"2027-12",{"name":5,"class":6}]