[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100652405":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":19,"centralContacts":20,"locations":27,"responsibleParty":40,"collaborators":19,"id":42,"slug":43,"hasResults":44,"nctId":45,"briefTitle":46,"officialTitle":46,"acronym":19,"eligibilityCriteria":47,"healthyVolunteers":48,"sex":49,"minAge":50,"maxAge":51,"enrollmentInfo":52,"targetDuration":19,"studyType":55,"phases":56,"briefSummary":58,"conditions":59,"keywords":60,"overallStatus":62,"whyStopped":19,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":72},{"fullName":5,"class":6},"Chung Shan Medical University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Split-Face Control Group","EXPERIMENTAL","\"All 10 participants in this group will undergo two different skincare regimens on randomly assigned sides of the face (left or right) for a duration of 28 days.\n\nOn the designated intervention side, participants will apply a green-bean-sized amount of Deep Microspicule Cream and gently massage, followed by the application of Deep Essence to dissolve the microspicules.\n\nOn the opposite control side, participants will apply Deep Essence only as a within-subject control. Both regimens are to be applied three times per week (Mondays, Wednesdays, and Saturdays) at night after cleansing.",[13],"Other: Deep Microspicule Cream",[15],{"type":6,"name":16,"description":17,"armGroupLabels":18,"otherNames":19},"Deep Microspicule Cream","\"A topical cream (Deep Microspicule Cream) utilizing patented crystal microspicule technology to encapsulate Penghu seaweed extracts (including Caulerpa microphysa, Sargassum hemiphyllum, and Botryocladia leptopoda). These ingredients possess potential anti-inflammatory, antioxidant, and collagen-promoting properties.\n\nParticipants will apply a green-bean-sized amount of the cream strictly to the randomly assigned intervention side of the face (left or right). The cream should be massaged gently on the designated side to allow the microspicules to roll on the skin surface (avoiding harsh rubbing). This application regimen is to be performed three times per week (Mondays, Wednesdays, and Saturdays) at night after facial cleansing, for a total duration of 28 days.\"",[9],null,[21],{"name":22,"role":23,"phone":24,"phoneExt":25,"email":26},"You-Cheng Mr Shen, Ph.D.","CONTACT","886-4-24730022","12107","youcheng@csmu.edu.tw",[28],{"facility":5,"status":19,"city":29,"state":19,"zip":19,"country":30,"countryCode":31,"cosmosGeoPoint":32,"geoPoint":37,"contacts":38},"Taichung","Taiwan","TW",{"type":33,"coordinates":34},"Point",[35,36],120.6839,24.1469,{"lat":36,"lon":35},[39],{"name":22,"role":23,"phone":24,"phoneExt":25,"email":26},{"type":41,"investigatorFullName":19,"investigatorTitle":19,"investigatorAffiliation":19,"oldNameTitle":19,"oldOrganization":19},"SPONSOR","100652405","efficacy-validation-of-deep-microspicule-cream-for-anti-aging-and-whitening-on-mature-skin-100652405",false,"NCT07774260","Efficacy Validation of Deep Microspicule Cream for Anti-aging and Whitening on Mature Skin","Inclusion Criteria:\n\n* Healthy male or female participants aged 40-65 years.\n* Presence of at least one facial aging or hyperpigmentation feature (e.g., eye area sagging, eye bags, crow's feet, fine lines, freckles, sun spots, uneven skin tone, or dullness).\n* Willing to complete 3 study visits within 4 weeks, comply with instrumental measurements, and maintain product logs.\n* Willing to sign the Informed Consent Form (ICF).\n\nExclusion Criteria:\n\n* Received facial aesthetic treatments (e.g., lasers, chemical peels, microneedling, energy-based therapies) within 4 weeks.\n* Used topical\u002Foral retinoic acid or strong whitening creams (e.g., high-concentration hydroquinone) within 4 weeks.\n* Severe sensitive skin, active atopic dermatitis, or obvious facial skin lesions\u002Finfections.\n* Facial salon or exfoliation treatments more frequent than once every 2 weeks.\n* Known allergy to seaweed-derived ingredients or product preservative systems.\n* Uncontrolled systemic diseases (e.g., diabetes, kidney\u002Fliver\u002Fcardiovascular diseases, severe infections, endocrine disorders, or cancer).\n* Pregnant, lactating, or planning to become pregnant.\n* Deemed unsuitable for participation by the investigator.",true,"ALL","40 Years","65 Years",{"count":53,"type":54},10,"ESTIMATED","INTERVENTIONAL",[57],"NA","This study is a single-center, prospective, split-face self-controlled pilot trial designed to evaluate the anti-aging and whitening efficacy of the \"Deep Microspicule Cream\" (containing patented crystal microspicules encapsulating Penghu seaweed extract) on mature skin.",[46],[61],"Microspicule, Anti-aging, Whitening","NOT_YET_RECRUITING","2026-08-14",{"date":65,"type":66},"2026-08-19","ACTUAL",{"date":68,"type":54},"2026-09-01",{"date":70,"type":54},"2026-10-30",{"name":5,"class":6},1]