[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100646963":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":24,"centralContacts":28,"locations":12,"responsibleParty":34,"collaborators":12,"id":36,"slug":37,"hasResults":38,"nctId":39,"briefTitle":40,"officialTitle":40,"acronym":41,"eligibilityCriteria":42,"healthyVolunteers":38,"sex":43,"minAge":12,"maxAge":12,"enrollmentInfo":44,"targetDuration":12,"studyType":47,"phases":48,"briefSummary":50,"conditions":51,"keywords":56,"overallStatus":61,"whyStopped":12,"lastUpdateSubmitDate":62,"lastUpdatePostDateStruct":63,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":12},{"fullName":5,"class":6},"University of Alberta","OTHER",[8,13],{"label":9,"type":10,"description":11,"interventionNames":12},"Usual Care","NO_INTERVENTION","Participants in the usual care arm will have data collected (baseline demographics, medical history, laboratory values, medication usage and clinical outcomes) from their health record. Usual care will include follow-up with their primary cardiologist, primary care physician, cardiac rehabilitation team and community pharmacy as per standards of care across Canada and the CCS Dyslipidemia Guidelines. This data will include information regarding their cholesterol levels and cholesterol treatments received as per standard of care practices.",null,{"label":14,"type":15,"description":16,"interventionNames":17},"Quality-improvement intervention","ACTIVE_COMPARATOR","Participants in the intervention will provide verbal consent to participate. In addition to data collection, Pharmacist contact will occur monthly until their cholesterol levels at target or if they no longer wish to participate in the study, no further changes in medications will occur and no further follow-up is required. Participation in the interventional arm can last up to 6 months.",[18],"Other: Pharmacist-led lipid optimization pathway",[20],{"type":6,"name":21,"description":22,"armGroupLabels":23,"otherNames":12},"Pharmacist-led lipid optimization pathway","Referral to a centralized, pharmacist-led, telephone clinic for optimization of dyslipidemia management",[14],[25],{"name":26,"affiliation":5,"role":27},"Pishoy Gouda, MD","PRINCIPAL_INVESTIGATOR",[29],{"name":30,"role":31,"phone":32,"phoneExt":12,"email":33},"Canadian VIGOUR Centre","CONTACT","(800) 707-9098","ehlocale@ualberta.ca",{"type":35,"investigatorFullName":12,"investigatorTitle":12,"investigatorAffiliation":12,"oldNameTitle":12,"oldOrganization":12},"SPONSOR","100646963","electronic-health-record-augmented-ldl-cholesterol-optimization-and-control-via-active-lipid-engagement-ehr-locale-a-quality-improvement-implementation-study-100646963",false,"NCT07685639","Electronic Health Record Augmented LDL-Cholesterol Optimization and Control Via Active Lipid Engagement (EHR-LOCALE): A Quality Improvement Implementation Study","EHR-LOCALE","Inclusion Criteria:\n\n1. Adults over the age of 18\n2. Resident of Alberta\n3. Individuals hospitalized with an acute coronary syndrome and have undergone coronary angiography.\n4. Able to participate in follow-up contact if randomized to the intervention arm\n\nExclusion Criteria:\n\n1\\. In-hospital mortality","ALL",{"count":45,"type":46},2000,"ESTIMATED","INTERVENTIONAL",[49],"NA","The purpose of this study is to determine whether a proactive, EHR-guided approach helps more individuals reach safe cholesterol levels, improves medication use, and reduces future heart attacks and strokes, compared to usual care.\n\nThe main question it aims to answer is:\n\n• Does the EHR-LOCALE pathway increases the proportion of patients who reach the LDL-cholesterol target of \\\u003C1.8 mmol\u002FL at 6 months?\n\nParticipants in the interventional group receive:\n\n* Pharmacist contact\n* Repeat lipid requisitions\n* Review of medications, adherence, and side effects\n* Treatment escalation according to national dyslipidemia guidelines",[52,53,54,55],"ACS (Acute Coronary Syndrome)","Hyperlipidemia","Dyslipidemia","Low-Density-Lipoprotein-cholesterol Level",[54,30,57,58,59,60],"LDL","ACS","triglycerides","lipid","NOT_YET_RECRUITING","2026-06-29",{"date":64,"type":65},"2026-07-06","ACTUAL",{"date":67,"type":46},"2026-08",{"date":69,"type":46},"2027-09",{"name":5,"class":6}]