[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100647154":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":25,"centralContacts":25,"locations":29,"responsibleParty":47,"collaborators":25,"id":49,"slug":50,"hasResults":51,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":25,"eligibilityCriteria":55,"healthyVolunteers":51,"sex":56,"minAge":57,"maxAge":25,"enrollmentInfo":58,"targetDuration":25,"studyType":61,"phases":62,"briefSummary":64,"conditions":65,"keywords":68,"overallStatus":75,"whyStopped":25,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":85},{"fullName":5,"class":6},"Imperial College London","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Visual EMG feedback with vibrotactile feedback","EXPERIMENTAL","Participants in the intervention group will receive visual EMG feedback combined with vibrotactile\u002Fhaptic feedback delivered through a wearable EMG-based device during attempted upper limb movements.",[13],"Device: Visual EMG feedback with vibrotactile feedback",{"label":15,"type":16,"description":17,"interventionNames":18},"Visual EMG feedback","ACTIVE_COMPARATOR","Participants in the control group will receive visual EMG feedback only and will complete the same assessment schedule as the intervention group.",[19],"Device: Visual EMG feedback",[21,26],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"DEVICE","Surface EMG sensors detect muscle activity and provide visual feedback. The device also delivers vibrotactile\u002Fhaptic feedback in the form of vibrations during attempted upper limb movements.",[9],null,{"type":22,"name":15,"description":27,"armGroupLabels":28,"otherNames":25},"The intervention consists of visual EMG feedback through a wearable EMG-based device during attempted upper limb movements. Surface EMG sensors detect muscle activity and provide visual feedback.",[15],[30],{"facility":31,"status":25,"city":32,"state":25,"zip":25,"country":33,"countryCode":34,"cosmosGeoPoint":35,"geoPoint":40,"contacts":41},"Charing Cross Hospital","London","United Kingdom","UK",{"type":36,"coordinates":37},"Point",[38,39],-0.12574,51.50853,{"lat":39,"lon":38},[42],{"name":43,"role":44,"phone":45,"phoneExt":25,"email":46},"Paul Bentley, PhD in Cognitive Neuroscience","CONTACT","00447969570854","p.bentley@imperial.ac.uk",{"type":48,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR","100647154","emg-directed-virtual-reality-training-for-motor-stroke-rehabilitation-100647154",false,"NCT07705256","EMG-Directed Virtual-Reality Training for Motor Stroke Rehabilitation","Pilot Study of EMG-Directed Virtual-Reality Experience Training for Motor Stroke Rehabilitation","Inclusion Criteria:\n\n* Aged 18 or over\n* Cognitive status that would permit for use \u002Fsupported use of intervention device and engagement in protocol related trainings\u002Fassessment. To be indicated by treating clinician at point of screening, formal capacity assessment to be conducted as appropriate. Refer to easy read patient information sheet (PIS) and training materials to support all patients presenting with specific cognitive and\u002For communication needs.\n* (We do not wish to exclude patients with cognitive impairment as this would limit the heterogeneity of our sample and generalizability of our findings, given the prevalence of cognitive impairment in stroke patients.)\n* Stroke diagnosis (can be first or subsequent stroke, unilateral haemorrhagic or ischemic) 2 weeks max post stroke at time of recruitment.\n* Can communicate in English, that is, sufficient for completion of intervention and outcome measures. A speech and language therapist (SLT) will be consulted if necessary to ensure all reasonable accommodations are made to support participation.\n* UL motor deficit post stroke (bilateral\u002Funilateral) (according to National Institutes of Health Stroke Score (NIHSS) item 5), distal UL power \\\u003C1 \u002F5 on the Oxford Rating Scale (Medical Research Council Manual Muscle Testing scale).\n\nExclusion Criteria:\n\n* Patients already enrolled an interventional neuro rehabilitation trial.\n* Patients enrolled in clinical trials that contraindicate co-enrolment.\n* Patients presenting with unstable medical conditions\u002Fmedical contraindications as determined by treating medical consultant (these patients may be approached at a later date should their condition improve).\n* Those registered blind\u002Fwith uncompensated\u002Funcorrected visual deficits, including severe neglect that prevents them from being able to focus on visually provided feedback.\n* Behavioural\u002Faffective dysfunction which could influence the ability of the person to engage with the research protocol and\u002For pose risk to the participating researchers (in circumstances such as follow-up community visits).\n* Other concomitant neurological disorders affecting upper extremity motor function (Multiple Sclerosis, Spinal Cord Injury, Brachial Plexus or Radial Nerve Injury).\n* Unremitting arm, wrist or hand pain at rest (Numeric Pain Rating Scale \\> 4). Consumption of caffeine 2 hours prior to assessment (assessment will be postponed to a later time).\n* Pre-existing UL impairment with known and significant disruption to range of motion, motor or functional performance (fracture, arthritic changes, other known musculoskeletal problems). Or pre-modified Rankin Score \\> 2.\n* Skin condition apparent on the ventral UE such that might place participant at risk of irritation in the context of repeated physical contact (such as that associated with the intervention).\n* Subsequent MRI that fails to confirm stroke\n* Chronic stroke patients whose stroke occurred in excess of 2.5 years ago\n* Patients whose cognitive impairment prevents them from following instructions","ALL","18 Years",{"count":59,"type":60},24,"ESTIMATED","INTERVENTIONAL",[63],"NA","This study is testing whether rehabilitation using muscle activity signals can help improve arm and hand movement in people after stroke or spinal cord injury.\n\nIn the main study, participants will use a virtual-reality feedback system that is controlled by surface electromyography (EMG). Surface EMG uses sensors placed on the skin to detect muscle activity. The feedback will help participants practise upper limb movements during rehabilitation.\n\nA related sub-study will run alongside the main study. In this sub-study, functional electrical stimulation will also be used to help activate muscles during training.\n\nThe study will assess whether these rehabilitation approaches improve upper limb function. It will also explore whether changes in biological or movement-related markers are linked with recovery.",[66,67],"Stroke","Spinal Cord Injuries (Complete and Incomplete)",[69,70,71,72,73,74],"Stroke rehabilitation","upper limb rehabilitation","EMG biofeedback","motor recovery","neurorehabilitation","spinal cord injury rehabilitation","NOT_YET_RECRUITING","2026-08-17",{"date":78,"type":79},"2026-08-18","ACTUAL",{"date":81,"type":60},"2026-07-27",{"date":83,"type":60},"2027-11-27",{"name":5,"class":6},1]