[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100645565":3},{"organization":4,"armGroups":7,"interventions":23,"overallOfficials":35,"centralContacts":43,"locations":54,"responsibleParty":73,"collaborators":77,"id":82,"slug":83,"hasResults":84,"nctId":85,"briefTitle":86,"officialTitle":87,"acronym":88,"eligibilityCriteria":89,"healthyVolunteers":84,"sex":90,"minAge":91,"maxAge":92,"enrollmentInfo":93,"targetDuration":96,"studyType":97,"phases":10,"briefSummary":98,"conditions":99,"keywords":104,"overallStatus":57,"whyStopped":10,"lastUpdateSubmitDate":109,"lastUpdatePostDateStruct":110,"startDateStruct":113,"completionDateStruct":115,"leadSponsor":117,"locationsCount":118},{"fullName":5,"class":6},"Evangelismos Hospital","OTHER",[8,15,19],{"label":9,"type":10,"description":11,"interventionNames":12},"Enteral and oral nutrition",null,"Participants undergoing total or partial pancreatectomy for a pancreatic tumor whose postoperative nutrition is delivered by the enteral route together with oral intake. Feeding route is not assigned by the study; it is determined by the treating surgical and nutrition support teams according to clinical status and tolerance, and recorded as an observed exposure. All participants in this cohort undergo indirect calorimetry and structured documentation of energy and protein intake during the early postoperative period.",[13,14],"Procedure: Pancreatectomy","Diagnostic Test: Indirect calorimetry",{"label":16,"type":10,"description":17,"interventionNames":18},"Parenteral nutrition","Participants undergoing total or partial pancreatectomy for a pancreatic tumor whose postoperative nutrition is delivered exclusively by the parenteral route, as determined clinically by the treating teams. As in the other cohorts, participants undergo indirect calorimetry and documentation of nutritional delivery, complications, and follow-up outcomes.",[13,14],{"label":20,"type":10,"description":21,"interventionNames":22},"Combined enteral and parenteral nutrition","Participants undergoing total or partial pancreatectomy for a pancreatic tumor who receive combined enteral and parenteral nutrition, as determined clinically by the treating teams. Participants undergo the same calorimetry, intake documentation, and follow-up assessments as the other cohorts.",[13,14],[24,31],{"type":25,"name":26,"description":27,"armGroupLabels":28,"otherNames":29},"PROCEDURE","Pancreatectomy","Total or partial pancreatectomy (including pancreaticoduodenectomy \u002F Whipple procedure and distal pancreatectomy) performed for a pancreatic tumor. This is the qualifying surgical exposure common to all participants. Applies to: Cohort 1, Cohort 2, Cohort 3.",[20,9,16],[30],"Indirect calorimetry",{"type":32,"name":30,"description":33,"armGroupLabels":34,"otherNames":10},"DIAGNOSTIC_TEST","Measurement of resting energy expenditure by indirect calorimetry (Cosmed Q-NRG+), performed under standardized fasting and steady-state conditions during the early postoperative period. This is the reference measurement against which predictive equations and weight-based targets are compared.",[20,9,16],[36,40],{"name":37,"affiliation":38,"role":39},"Kalliopi Anna Poulia, PhD","School of Food and Nutritional Sciences, Agricultural University of Athens","STUDY_CHAIR",{"name":41,"affiliation":42,"role":39},"Melina Dimitriou, PhD","m.dimitriou@go.uop.gr",[44,50],{"name":45,"role":46,"phone":47,"phoneExt":48,"email":49},"Dimitrios Karagiannis, PhD","CONTACT","2132045035","+30","jimkar_d@yahoo.com",{"name":51,"role":46,"phone":52,"phoneExt":48,"email":53},"Ζοι Bouloubassi, MSc","2132041685","zoippp@yahoo.com",[55],{"facility":56,"status":57,"city":58,"state":59,"zip":60,"country":61,"countryCode":62,"cosmosGeoPoint":63,"geoPoint":68,"contacts":69},"Evaggelismos General Hospital","RECRUITING","Athens","Attica","10676","Greece","GR",{"type":64,"coordinates":65},"Point",[66,67],23.72784,37.98376,{"lat":67,"lon":66},[70],{"name":71,"role":46,"phone":72,"phoneExt":10,"email":49},"Dimitrios Karagiannis","6937158640",{"type":74,"investigatorFullName":75,"investigatorTitle":76,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Dimitrios Karayiannis","Director, Department of Clinical Nutrition",[78,80],{"name":79,"class":6},"University of Peloponnese",{"name":81,"class":6},"Agricultural University of Athens","100645565","energy-expenditure-and-nutrition-after-pancreatic-surgery-100645565",false,"NCT07703813","Energy Expenditure and Nutrition After Pancreatic Surgery","Resting Energy Expenditure, Nutritional Intake, and Postoperative Outcomes in Patients Undergoing Total or Partial Pancreatectomy for Pancreatic Tumors: A Prospective Observational Cohort Study","NUTRI-PD","Inclusion Criteria:\n\n* Age 18 years or older\n* Scheduled to undergo total or partial pancreatectomy (including pancreaticoduodenectomy\u002FWhipple procedure or distal pancreatectomy) for a pancreatic tumor\n* Able to complete indirect calorimetry measurement by canopy or face mask for the required duration\n* Able to provide written informed consent\n\nExclusion Criteria:\n\n* Age under 18 years, greater than 75 years\n* Pregnancy\n* Inability to tolerate the calorimetry canopy or mask for the duration required for a valid measurement\n* Unable or unwilling to provide informed consent\n* patients already on preoperative enteral nutrition or unable to feed orally preoperatively","ALL","18 Years","75 Years",{"count":94,"type":95},150,"ESTIMATED","12 Months","OBSERVATIONAL","This prospective observational cohort study examines the energy requirements and nutritional care of patients undergoing total or partial pancreatectomy for pancreatic tumors. Patients undergoing pancreatectomy face major metabolic stress, a high burden of preoperative malnutrition, and frequent exocrine or endocrine insufficiency, yet procedure-specific nutritional guidance is limited. The study measures resting energy expenditure (REE) directly by indirect calorimetry during the early postoperative period and compares it with widely used predictive equations (Harris-Benedict, Schofield) and simplified weight-based targets (25 and 30 kcal\u002Fkg) to determine how accurately clinicians can estimate energy needs when calorimetry is unavailable. In the same patients, the study records the route of postoperative nutrition (enteral, parenteral, or combined), energy and protein intake relative to requirements, and diet-related symptoms, and follows postoperative complications, hospital readmission, mortality, and changes in body weight and body mass index through 3-6 months after surgery. By capturing measured energy expenditure and nutritional delivery in one cohort, the study aims to clarify whether adequacy of energy and protein intake, feeding route, or both influence recovery, and to provide primary data for developing individualized nutritional support protocols in this high-risk surgical population.",[100,101,102,103],"Whipple Procedures","Pancreatic Cancer","Pancreaticoduodenectomy","Pancreatic Neoplasms",[105,106,30,102,107,108],"Nutrition","Nutrition support","Surgical oncology nutrition","Postoperative nutrition","2026-07-09",{"date":111,"type":112},"2026-07-14","ACTUAL",{"date":114,"type":112},"2017-01-10",{"date":116,"type":95},"2028-11-10",{"name":5,"class":6},1]