[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100525323":3},{"organization":4,"outcomesModule":7,"designInfo":13,"detailedDescription":16,"studyPopulation":17,"armGroups":18,"interventions":12,"overallOfficials":22,"centralContacts":27,"locations":32,"responsibleParty":49,"collaborators":12,"id":51,"slug":52,"hasResults":53,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":12,"eligibilityCriteria":57,"healthyVolunteers":58,"sex":59,"minAge":60,"maxAge":61,"enrollmentInfo":62,"targetDuration":12,"studyType":65,"phases":12,"briefSummary":66,"conditions":67,"keywords":69,"overallStatus":71,"whyStopped":12,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":81},{"fullName":5,"class":6},"National Institutes of Health Clinical Center (CC)","NIH",{"primaryOutcomes":8,"secondaryOutcomes":12,"otherOutcomes":12},[9],{"measure":10,"description":10,"timeFrame":11},"To obtain nasal epithelium brushes from healthy volunteers for 1) establishment of upper respiratory tract organoids, 2) assay validation, and 3) use for research into the pathogenesis of emerging respiratory viruses.","10 years",null,{"allocation":12,"interventionModel":12,"interventionModelDescription":12,"primaryPurpose":12,"observationalModel":14,"timePerspective":15,"maskingInfo":12},"COHORT","CROSS_SECTIONAL","Study Description:\n\nThis is a repository protocol with prospective sample collection to provide samples needed for future studies of the pathogenesis of emerging respiratory viruses. Nasal brushings will be collected from approximately 100 healthy volunteers at RML and stored in the LV to be made available for future research studies that will be conducted under separate protocols, as applicable.\n\nPrimary Objective:\n\nTo obtain nasal epithelium brushes from healthy volunteers for 1) establishment of upper respiratory tract organoids, 2) assay validation, and 3) use for research into the pathogenesis of emerging respiratory viruses.","Healthy volunteers, aged 18 years and older, may be recruited from the general public, people working at and\u002For visiting Rocky Mountain Laboratories (RML), and NIH staff members and their family\u002Fcontacts.",[19],{"label":20,"type":12,"description":21,"interventionNames":12},"Healthy Volunteers","Healthy volunteers aged 18 years and older",[23],{"name":24,"affiliation":25,"role":26},"Emmie de Wit, Ph.D.","National Institute of Allergy and Infectious Diseases (NIAID)","PRINCIPAL_INVESTIGATOR",[28],{"name":24,"role":29,"phone":30,"phoneExt":12,"email":31},"CONTACT","(406) 375-7490","emmie.dewit@nih.gov",[33],{"facility":34,"status":12,"city":35,"state":36,"zip":37,"country":38,"countryCode":39,"cosmosGeoPoint":40,"geoPoint":45,"contacts":46},"Rocky Mountain Laboratories","Hamilton","Montana","59840","United States","US",{"type":41,"coordinates":42},"Point",[43,44],-114.16037,46.24687,{"lat":44,"lon":43},[47],{"name":24,"role":29,"phone":48,"phoneExt":12,"email":31},"406-375-7490",{"type":50,"investigatorFullName":12,"investigatorTitle":12,"investigatorAffiliation":12,"oldNameTitle":12,"oldOrganization":12},"SPONSOR","100525323","establishment-of-biobank-of-nasal-epithelium-samples-from-healthy-volunteers-100525323",false,"NCT06120244","Establishment of Biobank of Nasal Epithelium Samples From Healthy Volunteers","Establishment of a Biobank of Nasal Epithelium Samples From Healthy Volunteers","* INCLUSION CRITERIA:\n\nIn order to be eligible to participate in this study, an individual must meet all of the following criteria:\n\n* Aged \\>=18 years.\n* Able to provide informed consent.\n* Willing to allow biological samples and data to be stored for future research.\n\nEXCLUSION CRITERIA:\n\nAn individual who meets any of the following criteria will be excluded from participation in this\n\nstudy:\n\n* History of respiratory symptoms including but not limited to runny nose, coughing, congestion, and\u002For fever within the past 14 days.\n* NIH and laboratory staff with direct involvement in the operation or maintenance of the repository are excluded from participation.\n* An individual who has any condition that, in the judgment of the investigator, may put them at undue risk or make them unsuitable for participation in the study will be excluded.",true,"ALL","18 Years","99 Years",{"count":63,"type":64},120,"ESTIMATED","OBSERVATIONAL","Background:\n\nInfections in the lower respiratory tract (lungs) are the leading cause of death from infectious disease worldwide. This was true even before the COVID-19 pandemic. Respiratory viruses are still a major health threat. Many of these viruses infect people by penetrating the thin skin that lines the nose. These viruses can also spread easily to other people when they multiply in the tissues that line the nose. Researchers want to learn more about what these viruses do inside the nose, how they get from the nose to the lungs, and how they spread from person to person.\n\nObjective:\n\nTo collect cell samples from inside the noses of healthy people. These cells will be stored for use in future research on respiratory diseases.\n\nEligibility:\n\nHealthy volunteers aged 18 years and older.\n\nDesign:\n\nMost participants will have 1 visit on 1 day. They will be asked questions. Those who have a runny nose, coughing, congestion, or fever will be asked to wait up to 21 days before participating.\n\nParticipants will be given a slender swab with small bristles at the end. They will rub the inside of their nose with the swab. A clinic staff member will be present to help, if needed.\n\nParticipants will provide their name, age, and sex. This information will be encoded so that only certain researchers will know the participants identities.\n\nParticipants will not be contacted again....",[68],"Healthy",[70],"Nasal Epithelium","NOT_YET_RECRUITING","2026-10-12",{"date":74,"type":75},"2026-10-13","ACTUAL",{"date":77,"type":64},"2026-10-18",{"date":79,"type":64},"2033-10-31",{"name":25,"class":6},1]