[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100536559":3},{"organization":4,"armGroups":7,"interventions":17,"overallOfficials":36,"centralContacts":45,"locations":51,"responsibleParty":69,"collaborators":23,"id":72,"slug":73,"hasResults":74,"nctId":75,"briefTitle":76,"officialTitle":76,"acronym":23,"eligibilityCriteria":77,"healthyVolunteers":78,"sex":79,"minAge":80,"maxAge":81,"enrollmentInfo":82,"targetDuration":23,"studyType":85,"phases":86,"briefSummary":88,"conditions":89,"keywords":23,"overallStatus":54,"whyStopped":23,"lastUpdateSubmitDate":91,"lastUpdatePostDateStruct":92,"startDateStruct":95,"completionDateStruct":97,"leadSponsor":99,"locationsCount":100},{"fullName":5,"class":6},"Penn State University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"People with amyotrophic lateral sclerosis, age-matched speakers","EXPERIMENTAL","People with ALS and age-matched speakers will participate in structured communicative interaction.",[13,14,15,16],"Behavioral: Structured Communicative Interaction","Behavioral: Clear Speech","Behavioral: Unstructured communicative interaction","Behavioral: Clear Speech Structured Communicative Interaction",[18,24,28,32],{"type":19,"name":20,"description":21,"armGroupLabels":22,"otherNames":23},"BEHAVIORAL","Structured Communicative Interaction","Two interlocutors, one with ALS and a typical, unfamiliar interlocutor or an age-matched speaker and a typical interlocutor, will work together. On each trial, one of the interlocutors will be randomly chosen to be the \"speaker\" and the other will be the \"listener\". Each participant in the pair will view the same set of words on their screens. After one second, one of the words will be highlighted on the speaker's screen, they will say the word in the phrase \"Click on the \\_\\_\\_\\_ this time\", and the listener will click on it. After the listener has made their selection, both participants will receive feedback on trial success.",[9],null,{"type":19,"name":25,"description":26,"armGroupLabels":27,"otherNames":23},"Clear Speech","PALS and age-matched speakers will read critical words consisting of target segments (e.g., \"hid\", \"ship\", \"net\") in random order four times. These words will be embedded in the carrier phrase \"Click on the \\_\\_\\_ this time.\" Participations will be instructed to overenunciate the critical words.",[9],{"type":19,"name":29,"description":30,"armGroupLabels":31,"otherNames":23},"Unstructured communicative interaction","Two interlocutors, one with ALS and a typical, unfamiliar interlocutor or an age-matched speaker and a typical interlocutor, will work together. The pairs will be presented with two different versions of the same picture with eight differences chosen to elicit the same target segments (e.g., \"hid\", \"ship\", \"net\"). These pictures will be modified from the LUCID corpus. In total, pairs will complete four picture sets per session. Pairs will be given 5 minutes for each picture set.",[9],{"type":19,"name":33,"description":34,"armGroupLabels":35,"otherNames":23},"Clear Speech Structured Communicative Interaction","Two interlocutors, one with ALS and a typical, unfamiliar interlocutor or an age-matched speaker and a typical interlocutor, will work together. On each trial, one of the interlocutors will be randomly chosen to be the \"speaker\" and the other will be the \"listener\". Each participant in the pair will view the same set of words on their screens. After one second, one of the words will be highlighted on the speaker's screen, they will say the word in the phrase \"Click on the \\_\\_\\_\\_ this time\", and the listener will click on it. The speaker will be instructed to overenunciate the critical words. After the listener has made their selection, both participants will receive feedback on trial success.",[9],[37,41,43],{"name":38,"affiliation":39,"role":40},"Jimin Lee, PhD","The Pennsylvania State University","PRINCIPAL_INVESTIGATOR",{"name":42,"affiliation":39,"role":40},"Navin Viswanathan, PhD",{"name":44,"affiliation":39,"role":40},"Anne Olmstead, PhD",[46],{"name":47,"role":48,"phone":49,"phoneExt":23,"email":50},"Anne Olmstead, Ph.D.","CONTACT","814-867-3373","ajo150@psu.edu",[52],{"facility":53,"status":54,"city":55,"state":56,"zip":57,"country":58,"countryCode":59,"cosmosGeoPoint":60,"geoPoint":65,"contacts":66},"Speech Core, Pennsylvania State University","RECRUITING","University Park","Pennsylvania","16802","United States","US",{"type":61,"coordinates":62},"Point",[63,64],-77.85639,40.80201,{"lat":64,"lon":63},[67],{"name":38,"role":48,"phone":49,"phoneExt":23,"email":68},"jxl91@psu.edu",{"type":40,"investigatorFullName":70,"investigatorTitle":71,"investigatorAffiliation":5,"oldNameTitle":23,"oldOrganization":23},"Ji Min Lee, Ph.D.","Associate Professor","100536559","evaluating-verbal-communication-in-structured-interactions-theoretical-and-clinical-implications-100536559",false,"NCT06266403","Evaluating Verbal Communication in Structured Interactions: Theoretical and Clinical Implications","Inclusion Criteria:\n\nSpeakers with amyotrophic lateral sclerosis (ALS) (PALS-people with ALS)\n\n* diagnosis of ALS following the revised EL Escorial criteria\n* no history of other neurological conditions (e.g., stroke)\n* no cognitive impairment assessed by Telephone Montreal Cognitive Assessment (mini MoCA)\n* detectable speech disturbance according to the ALS Functional Rating Scale-Revised (ALSFRS-R)\n* the ability to produce single words\n* being a native speaker of American English (AE).\n\nAge-matched Speakers\n\n* passing the remote hearing screening\n* having no known speech, language, or neurological disorders per self-report\n* no cognitive impairment assessed by Telephone Montreal Cognitive Assessment (mini MoCA)\n* being a functionally native monolingual speaker of American English.\n\nUnfamiliar Interlocutors\n\n* passing the remote hearing screening\n* having no known speech, language or neurological disorders per self-report\n* being a native monolingual speaker of American English\n* having no experience communicating with people with dysarthria\n* being between the ages of 18 and 40.\n\nExclusion Criteria:\n\n* None - if volunteer meets the inclusion criteria, then they will be enrolled",true,"ALL","18 Years","90 Years",{"count":83,"type":84},300,"ESTIMATED","INTERVENTIONAL",[87],"NA","The goal of this clinical trial is to learn about the effect of communicative interaction on verbal communication in people with amyotrophic lateral sclerosis (ALS) and age-matched speakers.\n\nThe question is, What are the effects of communicative interaction on verbal communication in people with ALS?\n\nParticipants will read words and sentences while they are in a solo setting and interactive setting.",[90],"Amyotrophic Lateral Sclerosis","2026-08-06",{"date":93,"type":94},"2026-08-07","ACTUAL",{"date":96,"type":94},"2024-11-05",{"date":98,"type":84},"2029-02-28",{"name":5,"class":6},1]