[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100581445":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":24,"locations":29,"responsibleParty":48,"collaborators":19,"id":50,"slug":51,"hasResults":52,"nctId":53,"briefTitle":54,"officialTitle":54,"acronym":19,"eligibilityCriteria":55,"healthyVolunteers":52,"sex":56,"minAge":57,"maxAge":58,"enrollmentInfo":59,"targetDuration":19,"studyType":62,"phases":63,"briefSummary":65,"conditions":66,"keywords":69,"overallStatus":32,"whyStopped":19,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":80},{"fullName":5,"class":6},"M.D. Anderson Cancer Center","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"DeepDOF Images","EXPERIMENTAL","Participants will be approached by a trained research assistant. After informed consent is obtained, each participant will collect two cervical swabs (self-collected and\u002For provider-collected) as an optional procedure and stored for future research. VIA and\u002For colposcopy will be performed per standard of care. Cervical biopsy(ies) and\u002For LEEP will be performed per standard of care. The specimens will be imaged immediately using DeeDOF at the point of care and then submitted for standard histopathologic analysis as shown in Figure 1.",[13],"Device: DeepDOF Images",[15],{"type":16,"name":9,"description":17,"armGroupLabels":18,"otherNames":19},"DEVICE","Women referred for consultation for cervical biopsy(ies) and\u002For LEEP will be recruited into the experimental group of the study.",[9],null,[21],{"name":22,"affiliation":5,"role":23},"Kathleen M Schmeler, MD","PRINCIPAL_INVESTIGATOR",[25],{"name":22,"role":26,"phone":27,"phoneExt":19,"email":28},"CONTACT","(713) 854-9150","kschmele@mdanderson.org",[30],{"facility":31,"status":32,"city":33,"state":34,"zip":35,"country":36,"countryCode":37,"cosmosGeoPoint":38,"geoPoint":43,"contacts":44},"The University of Texas M. D. Anderson Cancer Center","RECRUITING","Houston","Texas","77030","United States","US",{"type":39,"coordinates":40},"Point",[41,42],-95.36327,29.76328,{"lat":42,"lon":41},[45,47],{"name":22,"role":26,"phone":46,"phoneExt":19,"email":28},"713-854-9150",{"name":22,"role":23,"phone":19,"phoneExt":19,"email":19},{"type":49,"investigatorFullName":19,"investigatorTitle":19,"investigatorAffiliation":19,"oldNameTitle":19,"oldOrganization":19},"SPONSOR","100581445","evaluation-of-a-novel-optical-microscope-with-a-deep-depth-of-field-deepdof-to-provide-histologic-quality-images-on-cervical-biopsies-and-loop-electrosurgical-excision-procedure-leep-specimens-at-the-point-of-care-100581445",false,"NCT06850402","Evaluation of a Novel Optical Microscope With a Deep Depth of Field (DeepDOF) to Provide Histologic-quality Images on Cervical Biopsies and Loop Electrosurgical Excision Procedure (LEEP) Specimens at the Point-of-care","Inclusion Criteria:\n\n1. Women aged 25 - 49 years\n2. women undergoing cervical biopsy and\u002For LEEP\n3. Women who are not pregnant and with a negative pregnancy test (within 3 days of enrollment)\n4. Willing and capable of providing informed consent\n\nExclusion Criteria:\n\n1. Women under 25 or over 49 years of age\n2. Women not undergoing cervical biopsy or LEEP\n3. Women who are pregnant","FEMALE","25 Years","49 Years",{"count":60,"type":61},400,"ESTIMATED","INTERVENTIONAL",[64],"NA","All patients will be enrolled in Mozambique and Brazil. They will provide informed consent to use their cervical biopsy and\u002For LEEP specimens for imaging with DeepDOF prior to sending for standard of care processing and interpretation.",[67,68],"Cervical Cancer","HIV",[70],"HPV DNA Testing","2026-08-17",{"date":73,"type":74},"2026-08-18","ACTUAL",{"date":76,"type":74},"2025-09-22",{"date":78,"type":61},"2028-09-01",{"name":5,"class":6},1]