[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100649634":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":31,"locations":37,"responsibleParty":54,"collaborators":58,"id":61,"slug":62,"hasResults":63,"nctId":64,"briefTitle":65,"officialTitle":65,"acronym":26,"eligibilityCriteria":66,"healthyVolunteers":63,"sex":67,"minAge":68,"maxAge":69,"enrollmentInfo":70,"targetDuration":26,"studyType":73,"phases":74,"briefSummary":76,"conditions":77,"keywords":26,"overallStatus":40,"whyStopped":26,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":91},{"fullName":5,"class":6},"First Teaching Hospital of Tianjin University of Traditional Chinese Medicine","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Active TES Group","EXPERIMENTAL","Participants receive transcutaneous electrical stimulation at hand Jing-Well acupoints (Shaoze SI1, Shangyang LI1, Zhongchong PC9, Guanchong SJ1, Shaochong HT9, and Dadun LR1) using a portable stimulator. Stimulation parameters: 10 Hz square wave, pulse width 320 μs, intensity adjusted to individual tolerance (typically 0-1 mA), 30 minutes per session, 6 sessions per week for 4 consecutive weeks (24 sessions total).",[13],"Device: Transcutaneous Electrical Stimulation at Jing-Well Acupoints",{"label":15,"type":16,"description":17,"interventionNames":18},"Sham TES Group","SHAM_COMPARATOR","Participants receive sham transcutaneous electrical stimulation at hand Jing-Well acupoint locations using an identical-appearing device with the same electrode placement pattern as the active group. The device delivers ineffective stimulation (0 Hz, no current output) while maintaining identical visual and tactile feedback. Sessions follow the same schedule as the active group: 30 minutes per session, 6 sessions per week for 4 consecutive weeks (24 sessions total).",[19],"Device: Transcutaneous Sham Electrical Stimulation at Jing-Well Acupoints",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","Transcutaneous Electrical Stimulation at Jing-Well Acupoints","Device-based transcutaneous electrical stimulation (TES) delivered to six hand Jing-Well acupoints: Shaoze (SI1), Shangyang (LI1), Zhongchong (PC9), Guanchong (SJ1), Shaochong (HT9), and Dadun (LR1). A custom-designed portable electrical stimulator (model YM-JX-V01, manufactured by Yimai Artificial Intelligence Medical Technology (Tianjin) Co., Ltd.) is used with disposable self-adhesive reference electrodes (4 × 4 cm) and stimulation electrodes (diameter 5 mm). Stimulation parameters: square wave, frequency 10 Hz, pulse width 320 μs, intensity individually titrated to sensory threshold (typically 0-1 mA), session duration 30 minutes. Treatment schedule: 6 sessions per week (Monday-Saturday) for 4 consecutive weeks, totaling 24 sessions. Electrodes are placed bilaterally at the designated acupoints according to WHO Standard Acupuncture Point Locations.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Transcutaneous Sham Electrical Stimulation at Jing-Well Acupoints","Device-based sham transcutaneous electrical stimulation (TES) delivered to six hand Jing-Well acupoints: Shaoze (SI1), Shangyang (LI1), Zhongchong (PC9), Guanchong (SJ1), Shaochong (HT9), and Dadun (LR1). A custom-designed portable electrical stimulator with open-circuit design (model YM-JX-V01, manufactured by Yimai Artificial Intelligence Medical Technology (Tianjin) Co., Ltd.) is used with disposable self-adhesive reference electrodes (4 × 4 cm) and stimulation electrodes (diameter 5 mm). The device delivers ineffective stimulation (0 Hz, no current output) while maintaining identical visual and tactile feedback. Sessions follow the same schedule as the active group: 30 minutes per session, 6 sessions per week for 4 consecutive weeks (24 sessions total). Electrodes are placed bilaterally at the designated acupoints according to WHO Standard Acupuncture Point Locations.",[15],[32],{"name":33,"role":34,"phone":35,"phoneExt":26,"email":36},"Liang Gao","CONTACT","8618722216295","Gaoliang202605@163.com",[38],{"facility":39,"status":40,"city":41,"state":42,"zip":43,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"The First Teaching Hospital of Tianjin University of Traditional Chinese Medicine","RECRUITING","Tianjin","Tianjin Municipality","300073","China","CN",{"type":47,"coordinates":48},"Point",[49,50],117.17667,39.14222,{"lat":50,"lon":49},[53],{"name":33,"role":34,"phone":35,"phoneExt":26,"email":36},{"type":55,"investigatorFullName":56,"investigatorTitle":57,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"PRINCIPAL_INVESTIGATOR","Gao Liang","Associate Chief Physician, Department of Acupuncture, First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine",[59],{"name":60,"class":6},"Tianjin University of Traditional Chinese Medicine","100649634","evaluation-of-clinical-efficacy-and-mechanism-of-hand-jing-well-acupoint-transcutaneous-electrical-stimulation-in-improving-post-stroke-cognitive-impairment-100649634",false,"NCT07736885","Evaluation of Clinical Efficacy and Mechanism of Hand Jing-Well Acupoint Transcutaneous Electrical Stimulation in Improving Post-Stroke Cognitive Impairment","Inclusion Criteria:\n\n1. Aged 35-80 years;\n2. Stroke duration within 2 weeks to 6 months post-onset;\n3. Cognitive impairment confirmed by neuropsychological assessment: Montreal Cognitive Assessment (MoCA) score \\\u003C 26;\n4. Clinical evaluation excludes delirium, major depressive disorder, schizophrenia, or other primary psychiatric\u002Fbehavioral disorders as the principal cause of current cognitive impairment. No history of other known neurological diseases that may cause cognitive impairment (e.g., multiple sclerosis, encephalitis, Parkinson's disease, post-traumatic dementia, normal pressure hydrocephalus, etc.);\n5. No severe aphasia; able to cooperate with scale assessments and complete the treatment protocol required by this study;\n6. Voluntary participation in this study; the participant or their legally authorized representative has signed the informed consent form.\n\nExclusion Criteria:\n\n1. Unstable vital signs or life-threatening comorbidities;\n2. Implanted devices (cardiac pacemaker\u002Fdefibrillator, deep brain stimulator, etc.);\n3. History of epilepsy or epileptic seizures;\n4. Pregnant or lactating women;\n5. Concurrent use of other medications affecting cognitive function;\n6. Allergy to the study intervention device or history of serious adverse reactions;\n7. Severe arrhythmia, malignant hypertension, or severe dysfunction of vital organs (heart, liver, kidney, etc.);\n8. Individuals unable to participate in treatment due to severe hearing or visual impairment, or bilateral limb paralysis.","ALL","35 Years","80 Years",{"count":71,"type":72},70,"ESTIMATED","INTERVENTIONAL",[75],"NA","This study evaluates a non-invasive electrical stimulation therapy applied to specific acupoints on the fingers (called Jing-Well points) to improve thinking and memory problems after stroke.\n\nPurpose: Many stroke survivors develop cognitive difficulties (problems with memory, attention, and decision-making). Current treatments are limited. This study tests whether gentle electrical stimulation to hand acupoints can improve these symptoms.\n\nWho can participate: Adults aged \\[35-80\\] who have had an ischemic stroke and now have mild to moderate cognitive impairment.\n\nWhat happens: Participants will be randomly assigned to receive either (1) active electrical stimulation to hand Jing-Well points, (2) sham (fake) stimulation. Treatment will last 4 weeks, 6 sessions per week, each 30 minutes, with a stimulation frequency of 10 Hz and intensity adjusted to each participant's tolerance. Cognitive tests and brain imaging will be done before and after treatment.\n\nPotential benefits: Participants may experience improved cognitive function. The study will also help researchers understand how this therapy works in the brain.\n\nRisks: The electrical stimulation may cause mild tingling or skin irritation at the electrode sites. Brain imaging is non-invasive and safe. All procedures will be performed by trained professionals.",[78,79,80,81],"Post-Stroke Cognitive Impairment (PSCI)","Ischemic Stroke","Cognitive Dysfunction, Cognitive Disorder","Hemorrhagic Strokes","2026-07-26",{"date":84,"type":85},"2026-07-30","ACTUAL",{"date":87,"type":72},"2026-08-15",{"date":89,"type":72},"2027-03-30",{"name":5,"class":6},1]