[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100647665":3},{"organization":4,"armGroups":7,"interventions":13,"overallOfficials":20,"centralContacts":25,"locations":35,"responsibleParty":52,"collaborators":19,"id":55,"slug":56,"hasResults":57,"nctId":58,"briefTitle":59,"officialTitle":60,"acronym":19,"eligibilityCriteria":61,"healthyVolunteers":62,"sex":63,"minAge":64,"maxAge":19,"enrollmentInfo":65,"targetDuration":19,"studyType":68,"phases":69,"briefSummary":71,"conditions":72,"keywords":74,"overallStatus":38,"whyStopped":19,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":83,"completionDateStruct":85,"leadSponsor":87,"locationsCount":88},{"fullName":5,"class":6},"Medical University of Vienna","OTHER",[8],{"label":9,"type":6,"description":10,"interventionNames":11},"FAPI PET\u002FCT scan","All included patients will have a FAPI PET\u002FCT scan",[12],"Diagnostic Test: PET\u002FCT scan",[14],{"type":15,"name":16,"description":17,"armGroupLabels":18,"otherNames":19},"DIAGNOSTIC_TEST","PET\u002FCT scan","Included patients will undergo one PET\u002FCT scan with 68GA-FAPI tracer application",[9],null,[21],{"name":22,"affiliation":23,"role":24},"Rainer Oberbauer, MD, PhD","Medical University of Vienna, Internal Medicine III, Department of Nephrology and Dialysis","PRINCIPAL_INVESTIGATOR",[26,31],{"name":27,"role":28,"phone":29,"phoneExt":19,"email":30},"Constantin N Aschauer, MD","CONTACT","004314040043910","constantin.aschauer@muv.ac.at",{"name":32,"role":28,"phone":33,"phoneExt":19,"email":34},"Rainer Oberbauer, MD, PhD, MD, PhD","004314040043900","rainer.oberbauer@meduniwien.ac.at",[36],{"facility":37,"status":38,"city":39,"state":40,"zip":41,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"General hospital Vienna","RECRUITING","Vienna","State of Vienna","1090","Austria","AT",{"type":45,"coordinates":46},"Point",[47,48],16.37208,48.20849,{"lat":48,"lon":47},[51],{"name":27,"role":28,"phone":29,"phoneExt":19,"email":30},{"type":24,"investigatorFullName":53,"investigatorTitle":54,"investigatorAffiliation":5,"oldNameTitle":19,"oldOrganization":19},"Rainer Oberbauer","Professor, Dr.med Rainer Oberbauer PhD","100647665","evaluation-of-kidney-fibrosis-via-fapi-petct-100647665",false,"NCT07712679","Evaluation of Kidney Fibrosis Via FAPI PET\u002FCT","Evaluation of Renal Renal Fibrosis Vie FAPI-PET-CT: a Prospective Non-randomized Open-label Single-center Pilot Study","Inclusion Criteria:\n\n* Histological workup of native kidney present\n\nExclusion Criteria:\n\n* Age \\\u003C18\n* Pregnancy",true,"ALL","18 Years",{"count":66,"type":67},30,"ESTIMATED","INTERVENTIONAL",[70],"NA","Interstitial fibrosis is a hallmark of progression in chronic kidney disease (CKD), yet it can presently be assessed only by kidney biopsy, which is invasive and prone to sampling error.\n\nIn recent years the advances in molecular imaging, especially high spatial and temporal resolution of the scanners and the development of radiopharmaceuticals to visualize metabolic processes or immune cells have been significant, opening promising possibilities in multiple fields. It was demonstrated that in autoimmune diseases as Crohns disease the use of fibrosis markers, as 68Ga-FAPI tracer in PET\u002FMRI could adequately reflect the amount of fibrosis found in histologic work up of tissue specimens in the gut. Also first data in small studies including patients with chronic kidney disease showed promising results indicating that tracer uptake could reflect the degree of fibrosis.\n\nThis study aims to investigate the utility of PET\u002FCT imaging with a \\[68Ga\\]-DOTA.SA.FAPi tracer to reflect the degree of fibrosis found in the histological work up. We hypothesize that PET\u002FCT findings reflect histological found fibrotic changes in kidney biopsies, potentially offering a superior alternative due to its non-invasive nature and the possibility to capture the entire organ.",[73],"Chronic Kidney Disease",[75,76,77,78],"Chronic kidney disease","PET\u002FCT","FAPI Imaging","Fibrosis","2026-07-14",{"date":81,"type":82},"2026-07-17","ACTUAL",{"date":84,"type":82},"2025-09-05",{"date":86,"type":67},"2027-09-01",{"name":5,"class":6},1]