[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100567921":3},{"organization":4,"outcomesModule":7,"designInfo":38,"detailedDescription":22,"studyPopulation":22,"armGroups":45,"interventions":58,"overallOfficials":22,"centralContacts":69,"locations":75,"responsibleParty":93,"collaborators":97,"id":100,"slug":101,"hasResults":102,"nctId":103,"briefTitle":104,"officialTitle":105,"acronym":22,"eligibilityCriteria":106,"healthyVolunteers":102,"sex":107,"minAge":108,"maxAge":109,"enrollmentInfo":110,"targetDuration":22,"studyType":113,"phases":114,"briefSummary":116,"conditions":117,"keywords":22,"overallStatus":77,"whyStopped":22,"lastUpdateSubmitDate":119,"lastUpdatePostDateStruct":120,"startDateStruct":123,"completionDateStruct":125,"leadSponsor":127,"locationsCount":128},{"fullName":5,"class":6},"Peking University Third Hospital","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":27,"otherOutcomes":22},[9,13,16,20,23],{"measure":10,"description":11,"timeFrame":12},"Cross-sectional area of the quadriceps","Using MRI，Up to 6 weeks","Before 1st practice, and after 12th practice (6 weeks * 2 practices\u002Fweek = 12 practices)",{"measure":14,"description":15,"timeFrame":12},"Cross-sectional area of the hamstrings","using MRI， Up to 6 weeks",{"measure":17,"description":18,"timeFrame":19},"Peak flexion and extension knee torque","Using an integrated torque sensor","During each practice (6 weeks * 2 practices\u002Fweek = 12 practices).",{"measure":21,"description":22,"timeFrame":19},"Average flexion and extension knee torque",null,{"measure":24,"description":25,"timeFrame":26},"Flexion and extension knee work","Work=Torque\\*Speed","In each ptractice (6 weeks * 2 practices \u002Fweek = 12 practices).",[28,31,34],{"measure":29,"description":30,"timeFrame":26},"Thigh circumference","10 cm proximal to the superior pole of the patella",{"measure":32,"description":33,"timeFrame":12},"Knee joint pain score (VAS score)","Up to 6 weeks，max. =100, min. =0, Visual Analogue Scale=VSA, A higher score indicates greater pain intensity.",{"measure":35,"description":36,"timeFrame":37},"Surface electromyography signals of quadricep and hamstrings","SEMG signals are used to evaluate the instant effect brought by the optimal stiffness.","During optimal stiffness measurements",{"allocation":39,"interventionModel":40,"interventionModelDescription":22,"primaryPurpose":6,"observationalModel":22,"timePerspective":22,"maskingInfo":41},"RANDOMIZED","PARALLEL",{"masking":42,"maskingDescription":22,"whoMasked":43},"SINGLE",[44],"PARTICIPANT",[46,52],{"label":47,"type":48,"description":49,"interventionNames":50},"Robot-assisted Rehabilitation","EXPERIMENTAL","In this clinical trial, 6 patients who meet the inclusion criteria will be enrolled in the experimental group to undergo rehabilitation using a portable isokinetic device.",[51],"Device: With robot assistance",{"label":53,"type":54,"description":55,"interventionNames":56},"None-robot-assisted Rehabilitation","ACTIVE_COMPARATOR","The control group will consist of 6 patients who meet the inclusion criteria and will undergo traditional isotonic and isometric rehabilitation",[57],"Behavioral: traditional rehabilitation",[59,64],{"type":60,"name":61,"description":62,"armGroupLabels":63,"otherNames":22},"DEVICE","With robot assistance","Use a portable isokinetic device",[47],{"type":65,"name":66,"description":67,"armGroupLabels":68,"otherNames":22},"BEHAVIORAL","traditional rehabilitation","Use traditional isotonic and isometric rehabilitation",[53],[70],{"name":71,"role":72,"phone":73,"phoneExt":22,"email":74},"Yuanzhen Yuan, Dr.","CONTACT","+8618811728786","yanggangfeng@buaa.edu.cn",[76],{"facility":5,"status":77,"city":78,"state":79,"zip":80,"country":81,"countryCode":82,"cosmosGeoPoint":83,"geoPoint":88,"contacts":89},"RECRUITING","Beijing","Beijing Municipality","100091","China","CN",{"type":84,"coordinates":85},"Point",[86,87],116.39723,39.9075,{"lat":87,"lon":86},[90],{"name":91,"role":72,"phone":92,"phoneExt":22,"email":74},"Yanggang Feng, Dr.","18811728786",{"type":94,"investigatorFullName":95,"investigatorTitle":96,"investigatorAffiliation":5,"oldNameTitle":22,"oldOrganization":22},"PRINCIPAL_INVESTIGATOR","Yuan Fuzhen","Principle Investigator",[98],{"name":99,"class":6},"Beihang University","100567921","evaluation-of-long-term-isokinetic-training-of-knee-joint-100567921",false,"NCT06674473","Evaluation of Long-term Isokinetic Training of Knee Joint","Effect and Evaluation of Long-term Isokinetic Training of Knee Joint Under the Influence of Stiffness","Inclusion Criteria:\n\n1. Age between 20-60 years.\n2. Patients with unilateral anterior cruciate ligament (ACL) rupture (with or without meniscus injury), posterior cruciate ligament (PCL) rupture, meniscal tear (M), and patellar dislocation (PD).\n\n4\\. Postoperative period of 3-6 months. 5. No restriction in knee extension or flexion movements.\n\nExclusion Criteria:\n\n1. Patients with major diseases or conditions such as coronary heart disease, myocardial infarction, heart failure, cerebral infarction, cerebral hemorrhage, or malignant tumors.\n2. Pregnant or breastfeeding women and other special populations.\n3. Patients who refuse to sign the informed consent form or are unable to complete the entire study process.\n4. Patients currently infected with human immunodeficiency virus (HIV), or with a history of infectious hepatitis B or C.\n5. Patients with concurrent medical issues, including but not limited to: (1) Uncontrolled hypertension (systolic blood pressure ≥160 mmHg and\u002For diastolic blood pressure ≥95 mmHg), congestive heart failure (New York Heart Association functional classification of stage III or IV). (2) Patients with mental incapacity or an inability to comprehend the study requirements.","ALL","20 Years","60 Years",{"count":111,"type":112},12,"ESTIMATED","INTERVENTIONAL",[115],"NA","The goal of this clinical trial is to assess the effectiveness of isokinetic rehabilitation training under optimal stiffness in patients undergoing knee joint rehabilitation. The main questions it aims to answer are:\n\n* Does isokinetic training under optimal stiffness lead to greater force exertion compared to traditional bodyweight training?\n* What are the long-term (6-week) effects of isokinetic training under optimal stiffness on joint flexibility and muscle strength? Researchers will compare the effects of isokinetic training under optimal stiffness to traditional bodyweight training to see if isokinetic training produces superior improvements in muscle strength, flexibility, and overall functional recovery.\n\nParticipants will:\n\n* Perform regular training sessions using a portable knee joint isokinetic trainer, customized to their optimal stiffness for maximum force exertion.\n* Engage in a 6-week rehabilitation program, with assessments at the beginning, and end of the study to evaluate changes in muscle strength, and functional recovery.",[118],"Knee Injuries and Disorders","2026-09-13",{"date":121,"type":122},"2026-09-15","ACTUAL",{"date":124,"type":122},"2024-11-06",{"date":126,"type":112},"2026-10-20",{"name":5,"class":6},1]