[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100647640":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":12,"locations":23,"responsibleParty":40,"collaborators":42,"id":45,"slug":46,"hasResults":47,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":51,"eligibilityCriteria":52,"healthyVolunteers":47,"sex":53,"minAge":54,"maxAge":10,"enrollmentInfo":55,"targetDuration":10,"studyType":58,"phases":10,"briefSummary":59,"conditions":60,"keywords":63,"overallStatus":26,"whyStopped":10,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":78},{"fullName":5,"class":6},"IRCCS Policlinico S. Donato","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":10},"IBD patients",null,"Patients with ulcerative colitis and Crohn' disease",[13,18],{"name":14,"role":15,"phone":16,"phoneExt":10,"email":17},"Vito Annese, Prof. PI","CONTACT","0039 3388261812","vitoannese1@gmail.com",{"name":19,"role":15,"phone":20,"phoneExt":21,"email":22},"Antonella Bianchi, Study coordinator","0039 025277","4722","antonella.bianchi2@gruopposandonato.it",[24],{"facility":25,"status":26,"city":27,"state":28,"zip":29,"country":30,"countryCode":31,"cosmosGeoPoint":32,"geoPoint":37,"contacts":38},"Gastroenterology IRCCS San Donato Policlinic","RECRUITING","San Donato Milanese","Mi","20097","Italy","IT",{"type":33,"coordinates":34},"Point",[35,36],9.26838,45.41047,{"lat":36,"lon":35},[39],{"name":14,"role":15,"phone":16,"phoneExt":10,"email":17},{"type":41,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[43],{"name":44,"class":6},"Asst Degli Spedali Civili Di Brescia","100647640","evaluation-of-the-accuracy-of-immunostaining-of-claudin-2-to-detect-active-or-inactive-inflammation-in-endoscopic-biopsies-of-ibd-100647640",false,"NCT07710287","Evaluation of the Accuracy of Immunostaining of Claudin 2 to Detect Active or Inactive Inflammation in Endoscopic Biopsies of IBD","Histologic Healing in IBD: Comparison of \"Standard\" Scores With Expression of Claudin 2 and Impact on Outcomes","LOGIC-2","Inclusion Criteria:\n\nConfirmed diagnosis of IBD\n\nExclusion Criteria:\n\nUnconfirmed diagnosis of IBD","ALL","18 Years",{"count":56,"type":57},100,"ESTIMATED","OBSERVATIONAL","In view of the increasing evidence of the importance of mucosal healing as a combination of endoscopic and histologic healing, and the complexity and lack of complete agreement of the evaluation of histologic healing in IBD, the aim of this study will be to evaluate the accuracy of a new methodology, the immunostaining for Claudine 2 as compared to others standard well-accepted scoring for histologic activity in IBD. The aim is compare the accuracy of this methodology and in addition the correlation with outcomes (i.e. relapse, hospitalization, surgery).",[61,62],"Ulcerative Colitis (UC)","Crohn Disease",[64,65,66,67,68],"Ulcerative colitis","Crohn's disease","Histology","Mucosa healing","Claudin","2026-07-13",{"date":71,"type":72},"2026-07-17","ACTUAL",{"date":74,"type":72},"2025-02-14",{"date":76,"type":57},"2027-09",{"name":5,"class":6},1]