[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100646630":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":24,"centralContacts":24,"locations":24,"responsibleParty":27,"collaborators":24,"id":31,"slug":32,"hasResults":33,"nctId":34,"briefTitle":35,"officialTitle":36,"acronym":24,"eligibilityCriteria":37,"healthyVolunteers":33,"sex":38,"minAge":39,"maxAge":40,"enrollmentInfo":41,"targetDuration":24,"studyType":44,"phases":45,"briefSummary":47,"conditions":48,"keywords":24,"overallStatus":50,"whyStopped":24,"lastUpdateSubmitDate":51,"lastUpdatePostDateStruct":52,"startDateStruct":55,"completionDateStruct":57,"leadSponsor":59,"locationsCount":24},{"fullName":5,"class":6},"Cairo University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"SHOFU Hard blocks","EXPERIMENTAL","CAD\u002FCAM Hybrid Ceramic, Overlay restored using the SHOFU cementation system.",[13],"Procedure: SHOFU Hard blocks",{"label":15,"type":16,"description":17,"interventionNames":18},"BRILLIANT Crios","ACTIVE_COMPARATOR","Resin-based Composite, Overlay restored using the Coltène cementation system.",[19],"Procedure: BRILLIANT Crios",[21,25],{"type":22,"name":9,"description":11,"armGroupLabels":23,"otherNames":24},"PROCEDURE",[9],null,{"type":22,"name":15,"description":17,"armGroupLabels":26,"otherNames":24},[15],{"type":28,"investigatorFullName":29,"investigatorTitle":30,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"PRINCIPAL_INVESTIGATOR","Sara Salem Sayed Ahmed","PhD Candidate","100646630","evaluation-of-wear-resistance-of-cadcam-hybrid-ceramic-and-nano-hybrid-composite-overlays-in-endodontically-treated-molars-and-their-effect-on-natural-antagonist-teeth-100646630",false,"NCT07689032","Evaluation of Wear Resistance of CAD\u002FCAM Hybrid Ceramic and Nano-Hybrid Composite Overlays in Endodontically Treated Molars and Their Effect on Natural Antagonist Teeth","Evaluation of Wear Resistance of CAD\u002FCAM Hybrid Ceramic and Nano-Hybrid Composite Overlays in Endodontically Treated Molars and Their Effect on Natural Antagonist Teeth: A 24-Month Randomized Clinical Trial","Inclusion Criteria:\n\n* Age between 22 and 45 years.\n* Low to moderate caries risk.\n* Normal occlusion.\n* Absence of signs or symptoms of temporomandibular joint (TMJ) disorders.\n* Satisfactory oral hygiene.\n* Medically fit to receive routine restorative dental treatment.\n* Permanent molars.\n* Asymptomatic endodontically treated teeth.\n* Homogeneous root canal fillings extending 1-2 mm from the radiographic apex.\n* Compound cavities.\n* Favorable occlusion.\n* Presence of both an adjacent tooth and a sound opposing tooth in occlusion\n\nExclusion Criteria:\n\n* \\* Presence of bruxism.\n\n  * Poor patient cooperation.\n  * Inability or unwillingness to attend follow-up appointments.\n  * Anticipated travel during the study period.\n  * Poor oral hygiene.\n  * Chronic or advanced periodontitis.\n  * Known allergies to any of the materials used in the study.\n  * Patients who are pregnant or breastfeeding.\n  * Teeth with \\\u003C1\" mm\" of residual wall thickness.\n  * Deep subgingival cavity margins.\n  * Severe periodontal problems.\n  * Radiographic signs of apical pathology.","ALL","22 Years","45 Years",{"count":42,"type":43},24,"ESTIMATED","INTERVENTIONAL",[46],"NA","This randomized clinical trial aims to to evaluate and compare the 24-month surface wear of the restoration and the surface wear of the opposing natural tooth structure of CAD\u002FCAM Hybrid Ceramic (SHOFU Hard blocks) versus Resin-based Composite (BRILLIANT Crios) overlays, utilizing a digital subtraction methodology (Intraoral Scanner and Geometrical Subtraction Software) in endodontically treated molar teeth.",[49],"Wear, Occlusal","NOT_YET_RECRUITING","2026-06-30",{"date":53,"type":54},"2026-07-07","ACTUAL",{"date":56,"type":43},"2026-07",{"date":58,"type":43},"2028-07",{"name":5,"class":6}]