[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100509809":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":28,"centralContacts":33,"locations":38,"responsibleParty":76,"collaborators":78,"id":81,"slug":82,"hasResults":83,"nctId":84,"briefTitle":85,"officialTitle":85,"acronym":24,"eligibilityCriteria":86,"healthyVolunteers":83,"sex":87,"minAge":88,"maxAge":24,"enrollmentInfo":89,"targetDuration":24,"studyType":92,"phases":93,"briefSummary":95,"conditions":96,"keywords":99,"overallStatus":64,"whyStopped":24,"lastUpdateSubmitDate":100,"lastUpdatePostDateStruct":101,"startDateStruct":104,"completionDateStruct":106,"leadSponsor":108,"locationsCount":109},{"fullName":5,"class":6},"Fred Hutchinson Cancer Center","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Group A: HIIT Exercise Program","EXPERIMENTAL","Participants will be allocated in a 1:1 ratio, using a permuted blocked design with varying block size. Study procedures will be conducted as follows:\n\n* Testing visits at Week 1 and 14 for physical exams, physical fitness and function assessments, survey questionnaires, and cardiopulmonary fitness assessment.\n* Virtual, aerobic training sessions three times weekly with trained oncology exercise specialist.",[13],"Behavioral: High-Intensity Interval Training Exercise Program",{"label":15,"type":10,"description":16,"interventionNames":17},"Group B: Waitlist Control","Participants will be allocated in a 1:1 ratio, using a permuted blocked design with varying block size. Study procedures will be conducted as follows:\n\n* Testing visits at Week 1 and 14 for physical exams, physical fitness and function assessments, and survey questionnaires.\n* Upon completion of post-intervention assessments, participants will have the option to take part in the 12-week HIIT exercise program.",[13],[19,25],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"BEHAVIORAL","High-Intensity Interval Training Exercise Program","Home-based, virtually supervised, aerobic exercise program of 36 sessions accessible via internet-enabled tablet (provided to participant if needed). Participants will be supplied with stationary bike, heart rate monitor, and blood pressure monitor.",[9],null,{"type":20,"name":21,"description":26,"armGroupLabels":27,"otherNames":24},"(Optionally) Home-based, virtually supervised, aerobic exercise program of 36 sessions accessible via internet-enabled tablet (provided to participant if needed). Participants will be supplied with stationary bike, heart rate monitor, and blood pressure monitor.",[15],[29],{"name":30,"affiliation":31,"role":32},"Dong-Woo Kang, PhD","Fred Hutch\u002FUniversity of Washington Cancer Consortium","PRINCIPAL_INVESTIGATOR",[34],{"name":30,"role":35,"phone":36,"phoneExt":24,"email":37},"CONTACT","206-667-5188","dkang@fredhutch.org",[39,53,58,63],{"facility":40,"status":41,"city":42,"state":43,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":24},"Beth Israel Deaconess Medical Center","COMPLETED","Boston","Massachusetts","02215","United States","US",{"type":48,"coordinates":49},"Point",[50,51],-71.05977,42.35843,{"lat":51,"lon":50},{"facility":54,"status":41,"city":42,"state":43,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":55,"geoPoint":57,"contacts":24},"Brigham and Women's Hospital",{"type":48,"coordinates":56},[50,51],{"lat":51,"lon":50},{"facility":59,"status":41,"city":42,"state":43,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":60,"geoPoint":62,"contacts":24},"Dana-Farber Cancer Institute",{"type":48,"coordinates":61},[50,51],{"lat":51,"lon":50},{"facility":31,"status":64,"city":65,"state":66,"zip":67,"country":45,"countryCode":46,"cosmosGeoPoint":68,"geoPoint":72,"contacts":73},"RECRUITING","Seattle","Washington","98109",{"type":48,"coordinates":69},[70,71],-122.33207,47.60621,{"lat":71,"lon":70},[74,75],{"name":30,"role":35,"phone":36,"phoneExt":24,"email":37},{"name":30,"role":32,"phone":24,"phoneExt":24,"email":24},{"type":77,"investigatorFullName":24,"investigatorTitle":24,"investigatorAffiliation":24,"oldNameTitle":24,"oldOrganization":24},"SPONSOR",[79],{"name":80,"class":6},"Prostate Cancer Foundation","100509809","exercise-for-tumor-suppressive-impact-in-men-with-prostate-cancer-at-high-risk-of-progression-on-active-surveillance-the-remove-trial-100509809",false,"NCT05918263","Exercise for Tumor Suppressive Impact in Men With Prostate Cancer at High-Risk of Progression on Active Surveillance: The REMOVE Trial","Inclusion Criteria:\n\n* Age ≥18 years.\n* Histologically diagnosed with localized prostate cancer.\n* Initiating or undergoing active surveillance.\n* Having a higher risk of progression, defined as meeting one or more of the following: (1) favorable- intermediate risk prostate tumor at diagnosis, (2) obesity (body mass index ≥ 30), and\u002For (3) self- identified as Black or African American.\n* No plans for invasive treatment for their prostate cancer in the 12 weeks following the time of enrollment.\n* Ability to understand and willingness to provide informed consent.\n\nExclusion Criteria:\n\n* Received any invasive curative-intent treatment for prostate cancer, including surgery, chemotherapy, radiation therapy, and hormonal therapy.\n* Patients with metastasis and\u002For other active malignancies (except basal cell carcinoma) and\u002For receiving treatment for those malignancies.\n* Participating in any (\\>0 min\u002Fweek) high-intensity exercise at the time of recruitment.\n* Having chronic medical conditions that are clinically unstable or uncontrolled with medications, deemed high-risk for exercise. These include but are not limited to unstable cardiac diseases, uncontrolled diabetes, and bone metastases with imminent risk of fracture.\n* Having a high risk for noncompliance with study procedures. This will be determined by the study team based on the history of missed oncology appointments (i.e., ≥3 no-shows in 6 months) and poor responsiveness during recruitment (i.e., ≥3 unreturned contacts).\n* Patients who are non-English speaking and unable to complete the participant surveys.","MALE","18 Years",{"count":90,"type":91},68,"ESTIMATED","INTERVENTIONAL",[94],"NA","The purpose of this study is to determine whether a 12-week, home-based, virtually supervised exercise program will slow cancer progression of prostate cancer among men with prostate cancer at high-risk of progression undergoing active surveillance.\n\nThe name of the study intervention involved in this study is:\n\nAerobic high-intensity interval training (HIIT) (training exercise intervention)",[97,98],"Prostate Cancer","Prostatic Neoplasms",[97,98],"2026-07-13",{"date":102,"type":103},"2026-07-15","ACTUAL",{"date":105,"type":103},"2024-01-01",{"date":107,"type":91},"2027-03-31",{"name":5,"class":6},4]