[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100632838":3},{"organization":4,"outcomesModule":7,"designInfo":19,"detailedDescription":18,"studyPopulation":18,"armGroups":25,"interventions":32,"overallOfficials":38,"centralContacts":42,"locations":51,"responsibleParty":67,"collaborators":18,"id":70,"slug":71,"hasResults":72,"nctId":73,"briefTitle":74,"officialTitle":74,"acronym":75,"eligibilityCriteria":76,"healthyVolunteers":72,"sex":77,"minAge":78,"maxAge":79,"enrollmentInfo":80,"targetDuration":18,"studyType":83,"phases":84,"briefSummary":85,"conditions":86,"keywords":88,"overallStatus":91,"whyStopped":18,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":101},{"fullName":5,"class":6},"University of Miami","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":18},[9],{"measure":10,"description":11,"timeFrame":12},"Protocol Completion Rate","Protocol Completion Rate is defined as the proportion of enrolled participants who complete both the supervised home-based HIIT exercise session and return all scheduled saliva samples to the laboratory.","From enrollment through completion of all study procedures (up to Day 1)",[14],{"measure":15,"description":16,"timeFrame":17},"Acceptability of the Exercise and Saliva Collection Protocol","Acceptability will be assessed using a participant-reported questionnaire adapted from the Theoretical Framework of Acceptability (TFA). The questionnaire evaluates acceptability across seven domains: affective attitude, burden, perceived effectiveness, ethicality, intervention coherence, opportunity costs, and self-efficacy. Each domain is assessed using 1-2 items rated on a 5-point Likert scale (1 = strongly disagree to 5 = strongly agree). Domain scores are averaged, and an overall Acceptability Index score is calculated, with higher scores indicating greater acceptability.","Immediately after protocol completion (Day 1)",null,{"allocation":20,"interventionModel":21,"interventionModelDescription":18,"primaryPurpose":22,"observationalModel":18,"timePerspective":18,"maskingInfo":23},"NA","SINGLE_GROUP","BASIC_SCIENCE",{"masking":24,"maskingDescription":18,"whoMasked":18},"NONE",[26],{"label":27,"type":28,"description":29,"interventionNames":30},"Home-Based High Intensity Interval Training (HIIT) Exercise Session + Saliva Collection","EXPERIMENTAL","Participants will complete a single supervised, online high intensity interval training (HIIT) exercise session with six bouts of 1-minute exercises performed at a moderate-to-high intensity lasting approximately 20 minutes. Saliva samples will be collected immediately prior to exercise, immediately following exercise, and 15 minutes post-exercise.",[31],"Behavioral: High-Intensity Interval Training (HIIT) Exercise",[33],{"type":34,"name":35,"description":36,"armGroupLabels":37,"otherNames":18},"BEHAVIORAL","High-Intensity Interval Training (HIIT) Exercise","Participants will complete a single supervised, online high intensity interval training (HIIT) exercise session lasting approximately 20 minutes. The exercise protocol consists of six 1-minute bouts with 1-minute rest intervals of moderate to high intensity bodyweight exercises, including movements such as lateral squats, wall pushups, and chair assisted sit to stands.",[27],[39],{"name":40,"affiliation":5,"role":41},"Nima Sharifi, MD","PRINCIPAL_INVESTIGATOR",[43,47],{"name":40,"role":44,"phone":45,"phoneExt":18,"email":46},"CONTACT","305-243-1350","nimasharifi@miami.edu",{"name":48,"role":44,"phone":49,"phoneExt":18,"email":50},"Elena Cortizas, MS","(305) 243-3593","ecortizas@med.miami.edu",[52],{"facility":53,"status":18,"city":54,"state":55,"zip":56,"country":57,"countryCode":58,"cosmosGeoPoint":59,"geoPoint":64,"contacts":65},"University of Miami Hospitals and Clinics","Miami","Florida","33141","United States","US",{"type":60,"coordinates":61},"Point",[62,63],-80.19366,25.77427,{"lat":63,"lon":62},[66],{"name":48,"role":44,"phone":49,"phoneExt":18,"email":50},{"type":41,"investigatorFullName":68,"investigatorTitle":69,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"Nima Sharifi","Professor and Scientific Director of the Desai Sethi Urology Institute","100632838","exercise-induced-steroid-changes-in-active-surveillance-for-prostate-cancer-100632838",false,"NCT07518888","Exercise-induced Steroid Changes in Active Surveillance for Prostate Cancer","ESCAPE","Inclusion Criteria:\n\n* Males 18 to 80 years old\n* Diagnosis of localized prostate cancer\n* Currently under active surveillance\n* Ability to perform moderate-to-high intensity physical activity as demonstrated by self-assessment using the Physical Activity Readiness Questionnaire (PAR-Q+)\n* Able to independently perform activities of daily living, without limitations in mobility\n* Ability to read, write, speak, and understand English\n* Able and willing to sign consent and comply with study requirements\n\nExclusion Criteria:\n\n* Males currently receiving treatment for prostate cancer\n* Diagnosis of metastatic prostate cancer\n* Individuals with medical conditions contraindicating exercise\n* Uncontrolled cardiovascular or circulatory diseases, hypertension, and diabetes, as determined by the study doctor or treating physician\n* Ongoing use of medications affecting steroid metabolism\n* Unable to sign consent and\u002For comply with study requirements","MALE","18 Years","80 Years",{"count":81,"type":82},49,"ESTIMATED","INTERVENTIONAL",[20],"The purpose of this research study is to understand how a short session of a home-based bodyweight high-intensity interval training (HIIT) affects steroid hormone levels in men on active surveillance for low-grade prostate cancer.",[87],"Prostate Cancer",[87,89,90],"Exercise","Steroids","NOT_YET_RECRUITING","2026-09-17",{"date":94,"type":95},"2026-09-21","ACTUAL",{"date":97,"type":82},"2026-10",{"date":99,"type":82},"2028-08",{"name":5,"class":6},1]