[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100648576":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":25,"locations":34,"responsibleParty":49,"collaborators":19,"id":51,"slug":52,"hasResults":53,"nctId":54,"briefTitle":55,"officialTitle":55,"acronym":19,"eligibilityCriteria":56,"healthyVolunteers":53,"sex":57,"minAge":58,"maxAge":59,"enrollmentInfo":60,"targetDuration":19,"studyType":63,"phases":64,"briefSummary":66,"conditions":67,"keywords":19,"overallStatus":37,"whyStopped":19,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":78},{"fullName":5,"class":6},"Buddhist Tzu Chi General Hospital","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Epidural electrical stimulation (EES)","EXPERIMENTAL","Participants will undergo implantation of a 16-electrode epidural spinal cord array. Following surgery, they will participate in a structured program of physical rehabilitation combined with epidural electrical stimulation.",[13],"Device: Epidural electrical stimulation (EES)",[15],{"type":16,"name":9,"description":17,"armGroupLabels":18,"otherNames":19},"DEVICE","Subjects will undergo a surgical procedure to implant a system that provides epidural electrical stimulation (EES) of the cervical spinal cord. After surgery, subjects will undergo a structured physical rehabilitation program and electrical stimulation.",[9],null,[21],{"name":22,"affiliation":23,"role":24},"Sheng-Tzung Tsai, M.D., Ph.D","Hualien Tzu Chi General Hospital","PRINCIPAL_INVESTIGATOR",[26,31],{"name":22,"role":27,"phone":28,"phoneExt":29,"email":30},"CONTACT","+886-3-856-1825","13054","flydream.tsai@gmail.com",{"name":32,"role":27,"phone":28,"phoneExt":29,"email":33},"Yu-Chen Chen, M.D., Ph.D.","spring810569@gmail.com",[35],{"facility":36,"status":37,"city":38,"state":19,"zip":19,"country":39,"countryCode":40,"cosmosGeoPoint":41,"geoPoint":46,"contacts":47},"Buddhist Tzu Chi Medical Foundation Hualien Tzu Chi Hospital","RECRUITING","Hualien City","Taiwan","TW",{"type":42,"coordinates":43},"Point",[44,45],121.60444,23.97694,{"lat":45,"lon":44},[48],{"name":22,"role":27,"phone":28,"phoneExt":29,"email":30},{"type":50,"investigatorFullName":19,"investigatorTitle":19,"investigatorAffiliation":19,"oldNameTitle":19,"oldOrganization":19},"SPONSOR","100648576","exploration-of-the-effectiveness-and-mechanism-of-personalized-epidural-electrical-stimulation-in-improving-upper-limb-function-in-participants-with-spinal-cord-injury-100648576",false,"NCT07722429","Exploration of the Effectiveness and Mechanism of Personalized Epidural Electrical Stimulation in Improving Upper Limb Function in Participants With Spinal Cord Injury","Inclusion Criteria:\n\n* Age between 18 and 70 years.\n* Duration since spinal cord injury ranging from 1 to 10 years.\n* Spinal cord injury level at or above T4.\n* MRI and\u002For CT imaging confirms adequate spinal cord decompression and spinal stability.\n* Stable vital signs and no dependence on mechanical ventilation.\n* Stable neurological and psychological status, with no history of neurological deterioration within the past 6 months (e.g., acute worsening of motor or sensory function, new-onset seizures, acute changes in muscle tone, or other neurological symptoms). Participants must be conscious, able to understand, and comply with study instructions. Clinical neurological examinations and imaging findings (MRI or CT) should demonstrate no new abnormalities.\n* Willingness to participate in and comply with rehabilitation programs.\n* Participants who have completed spinal cord electrical stimulation implantation surgery and\u002For are currently undergoing conventional rehabilitation therapy.\n\nExclusion Criteria:\n\n* Patients with untreated fractures of the upper extremities.\n* Patients with severe skin lesions or wounds that interfere with EMG electrode placement or the surgical sites for electrical stimulation implantation (e.g., chest\u002Fback, upper extremities, posterior cervical region, or subclavicular area).\n* Patients with a history of other neurological diseases.\n* Patients with known allergy or hypersensitivity to silver (Ag).","ALL","18 Years","70 Years",{"count":61,"type":62},20,"ESTIMATED","INTERVENTIONAL",[65],"NA","This study aimed to determine whether cervical spinal cord epidural electrical stimulation (EES) can activate upper-limb muscles in individuals with spinal cord injury.",[68],"Spinal Cord Injury(SCI)","2026-07-23",{"date":71,"type":72},"2026-07-24","ACTUAL",{"date":74,"type":72},"2025-11-17",{"date":76,"type":62},"2027-12-31",{"name":5,"class":6},1]