[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100655132":3},{"organization":4,"outcomesModule":7,"designInfo":26,"detailedDescription":25,"studyPopulation":25,"armGroups":36,"interventions":49,"overallOfficials":25,"centralContacts":57,"locations":63,"responsibleParty":78,"collaborators":25,"id":81,"slug":82,"hasResults":83,"nctId":84,"briefTitle":85,"officialTitle":86,"acronym":25,"eligibilityCriteria":87,"healthyVolunteers":83,"sex":88,"minAge":89,"maxAge":90,"enrollmentInfo":91,"targetDuration":25,"studyType":94,"phases":95,"briefSummary":53,"conditions":97,"keywords":25,"overallStatus":66,"whyStopped":25,"lastUpdateSubmitDate":99,"lastUpdatePostDateStruct":100,"startDateStruct":103,"completionDateStruct":105,"leadSponsor":107,"locationsCount":108},{"fullName":5,"class":6},"Menoufia University","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":25},[9],{"measure":10,"description":11,"timeFrame":12},"Total intraoperative fentanyl consumption","Total intraoperative fentanyl consumption (μg) = loading dose (1 μg\u002Fkg) + rescue boluses.","Intraoperative time, during surgery",[14,18,21],{"measure":15,"description":16,"timeFrame":17},"Postoperative morphine consumption","Postoperative morphine consumption (mg) at 24 hours.","The first 24 hours",{"measure":19,"description":20,"timeFrame":17},"First rescue fentanyl and time to first postoperative morphine","Time to first rescue fentanyl (from induction to first bolus) and Time to first postoperative morphine (from PACU arrival to first dose).",{"measure":22,"description":23,"timeFrame":24},"Pain scores","Pain scores (VAS score ranging 0-100) at Post Anesthetic Care Unit arrival, 1 hour, 2 hours, 6 hours, 12 hours, 24 hours.","Upon arrival, 1 hour, 2 hours, 6 hours, 12 hours, 24 hours.",null,{"allocation":27,"interventionModel":28,"interventionModelDescription":25,"primaryPurpose":29,"observationalModel":25,"timePerspective":25,"maskingInfo":30},"RANDOMIZED","PARALLEL","TREATMENT",{"masking":31,"maskingDescription":25,"whoMasked":32},"TRIPLE",[33,34,35],"PARTICIPANT","CARE_PROVIDER","OUTCOMES_ASSESSOR",[37,43],{"label":38,"type":39,"description":40,"interventionNames":41},"Group L (lidocaine)","ACTIVE_COMPARATOR","Bilateral EOIB + fentanyl 1 μg\u002Fkg loading + lidocaine 1.5 mg\u002Fkg loading + lidocaine infusion 1.5 mg\u002Fkg\u002Fh.",[42],"Drug: Investigatore hypothesize that adding a perioperative lidocaine infusion (1.5 mg\u002Fkg loading + 1.5 mg\u002Fkg\u002Fh) to bilateral EOIB and low dose fentanyl loading reduces intraoperative fentanyl consumption.",{"label":44,"type":45,"description":46,"interventionNames":47},"Group P (placebo)","PLACEBO_COMPARATOR","Bilateral EOIB + fentanyl 1 μg\u002Fkg loading + normal saline loading (equivalent volume) + normal saline infusion (equivalent rate).",[48],"Other: Bilateral EOIB + fentanyl 1 μg\u002Fkg loading + normal saline loading (equivalent volume) + normal saline infusion (equivalent rate).",[50,55],{"type":51,"name":52,"description":53,"armGroupLabels":54,"otherNames":25},"DRUG","Investigatore hypothesize that adding a perioperative lidocaine infusion (1.5 mg\u002Fkg loading + 1.5 mg\u002Fkg\u002Fh) to bilateral EOIB and low dose fentanyl loading reduces intraoperative fentanyl consumption.","Adding a perioperative lidocaine infusion (1.5 mg\u002Fkg loading + 1.5 mg\u002Fkg\u002Fh) to bilateral EOIB and low dose fentanyl loading reduces intraoperative fentanyl consumption (ANI guided rescue) compared to placebo, without increasing adverse events.",[38],{"type":6,"name":46,"description":46,"armGroupLabels":56,"otherNames":25},[44],[58],{"name":59,"role":60,"phone":61,"phoneExt":25,"email":62},"Nevine Mostafa Soliman","CONTACT","+201128861471","mostafanevine@gmail.com",[64],{"facility":65,"status":66,"city":67,"state":25,"zip":25,"country":68,"countryCode":69,"cosmosGeoPoint":70,"geoPoint":75,"contacts":76},"Faculty of Medicine","RECRUITING","Alexandria","Egypt","EG",{"type":71,"coordinates":72},"Point",[73,74],29.91582,31.20176,{"lat":74,"lon":73},[77],{"name":59,"role":60,"phone":61,"phoneExt":25,"email":62},{"type":79,"investigatorFullName":59,"investigatorTitle":80,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Assistant Professor","100655132","external-oblique-intercostal-block-with-or-without-intravenous-lidocaine-infusion-for-analgesia-in-patients-undergoing-gastric-bypass-surgery-100655132",false,"NCT07809425","External Oblique Intercostal Block With or Without Intravenous Lidocaine Infusion for Analgesia in Patients Undergoing Gastric Bypass Surgery","External Oblique Intercostal Block With or Without Intravenous Lidocaine Infusion for Analgesia in Patients Undergoing Gastric Bypass Surgery: a Randomized Controlled Trial","Inclusion Criteria:\n\n* Age 18-60 years.\n* BMI ≥ 35 kg\u002Fm².\n* ASA physical status II or III.\n* Scheduled for elective laparoscopic Roux en Y gastric bypass.\n* Ability to provide written informed consent.\n\nExclusion Criteria:\n\n* Refusal.\n* Allergy or contraindication to lidocaine, fentanyl, ropivacaine, or any study medication.\n* Chronic opioid use or dependence.\n* Significant hepatic (AST\u002FALT\\> 3× normal, cirrhosis) or renal impairment (CrCl\\\u003C 30 mL\u002Fmin).\n* Second or third degree AV block or significant bradyarrhythmia without pacemaker.\n* Coagulopathy, anticoagulation incompatible with regional anesthesia, or infection at block site.\n* Pregnancy or lactation.\n* Severe psychiatric or cognitive disorder.\n* Failed bilateral EOIB (absence of sensory loss in T6-T10 after 30 min) - excluded from analysis.","ALL","18 Years","60 Years",{"count":92,"type":93},100,"ESTIMATED","INTERVENTIONAL",[96],"NA",[98],"Obese Patients","2026-09-08",{"date":101,"type":102},"2026-09-11","ACTUAL",{"date":104,"type":93},"2026-09-15",{"date":106,"type":93},"2027-02-01",{"name":5,"class":6},1]