[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100653968":3},{"organization":4,"outcomesModule":7,"designInfo":14,"detailedDescription":13,"studyPopulation":13,"armGroups":20,"interventions":31,"overallOfficials":13,"centralContacts":37,"locations":43,"responsibleParty":57,"collaborators":13,"id":61,"slug":62,"hasResults":63,"nctId":64,"briefTitle":65,"officialTitle":66,"acronym":13,"eligibilityCriteria":67,"healthyVolunteers":68,"sex":69,"minAge":70,"maxAge":71,"enrollmentInfo":72,"targetDuration":13,"studyType":75,"phases":76,"briefSummary":78,"conditions":79,"keywords":13,"overallStatus":81,"whyStopped":13,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":91},{"fullName":5,"class":6},"University of Zakho","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":13},[9],{"measure":10,"description":11,"timeFrame":12},"Change in Wrinkle-Severity Reduction Index","Change in the mean bilateral crow's feet wrinkle depth (mm) from baseline to week 12, measured using Antera 3D. Three measurements will be obtained from each side, and the mean of the six measurements will be used as the participant-level value. Lower values indicate reduced wrinkle depth","Baseline to 12 weeks",null,{"allocation":15,"interventionModel":16,"interventionModelDescription":13,"primaryPurpose":17,"observationalModel":13,"timePerspective":13,"maskingInfo":18},"RANDOMIZED","PARALLEL","TREATMENT",{"masking":19,"maskingDescription":13,"whoMasked":13},"NONE",[21,27],{"label":22,"type":23,"description":24,"interventionNames":25},"intervention group","EXPERIMENTAL","Participants in the intervention group will complete a 12-week structured facial exercise program combined with daily habit modification related to skin health",[26],"Behavioral: Facial Exercise and Daily Habit Modification Program",{"label":28,"type":29,"description":30,"interventionNames":13},"control group","NO_INTERVENTION","Participants in the control group will maintain their usual daily routine and will not receive the structured facial exercise or daily habit modification program during the 12-week study period",[32],{"type":33,"name":34,"description":35,"armGroupLabels":36,"otherNames":13},"BEHAVIORAL","Facial Exercise and Daily Habit Modification Program","A 12-week structured program consisting of facial muscle exercises combined with daily habit modification related to skin health",[22],[38],{"name":39,"role":40,"phone":41,"phoneExt":13,"email":42},"dalshad m abdulrehman, ph.D .","CONTACT","009647501891419","dlshadm079@gmail.com",[44],{"facility":45,"status":13,"city":46,"state":47,"zip":48,"country":49,"countryCode":50,"cosmosGeoPoint":51,"geoPoint":56,"contacts":13},"Fitness Centers and Gyms in Duhok","Duhok","Duhok Governorate","42001","Iraq","IQ",{"type":52,"coordinates":53},"Point",[54,55],42.9879,36.86608,{"lat":55,"lon":54},{"type":58,"investigatorFullName":59,"investigatorTitle":60,"investigatorAffiliation":5,"oldNameTitle":13,"oldOrganization":13},"PRINCIPAL_INVESTIGATOR","Dalshad Mohamed Abdulrehman","principal investigator","100653968","facial-exercise-and-daily-habit-modification-program-for-skin-quality-and-wrinkle-severity-in-middle-aged-women-100653968",false,"NCT07792460","Facial Exercise and Daily Habit Modification Program for Skin Quality and Wrinkle Severity in Middle-Aged Women","Effects of a Combined Antioxidant Nutrition and Facial Exercise Program on Skin Quality and Wrinkle Severity in Middle-Aged Women","nclusion Criteria: Female participants aged 45-50 years. Willing and able to participate in the 12-week intervention program. Willing to maintain their usual skincare routine and comply with the study procedures. Able to provide informed consent.\n\nExclusion Criteria:\n\nCurrent smoking. Facial aesthetic procedures such as botulinum toxin injections, dermal fillers, laser treatment, chemical peels, or similar procedures within the predefined period before enrollment. Current dermatological disease or skin condition that may affect facial skin measurements. Uncontrolled chronic medical conditions that may influence skin health or participation in the intervention. Planned initiation of new skincare treatments, cosmetic products, or aesthetic procedures during the 12-week study period. Inability to perform the facial exercise program safely or comply with the study procedures",true,"FEMALE","45 Years","50 Years",{"count":73,"type":74},204,"ESTIMATED","INTERVENTIONAL",[77],"NA","This randomized controlled trial will evaluate the effectiveness of a 12-week program combining facial muscle exercises and daily habit modification for improving skin quality and reducing wrinkle severity in middle-aged women. Participants will be randomly allocated to an intervention group receiving the structured program or to a control group maintaining their usual routine. Skin-related outcomes will be assessed at baseline and after 12 weeks using standardized objective measurements.",[80],"Facail Skin Aging","NOT_YET_RECRUITING","2026-08-25",{"date":84,"type":85},"2026-08-28","ACTUAL",{"date":87,"type":74},"2026-09-01",{"date":89,"type":74},"2026-11-24",{"name":5,"class":6},1]