[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100130931":3},{"organization":4,"outcomesModule":7,"designInfo":16,"detailedDescription":19,"studyPopulation":20,"armGroups":11,"interventions":11,"overallOfficials":21,"centralContacts":26,"locations":11,"responsibleParty":32,"collaborators":11,"id":36,"slug":37,"hasResults":38,"nctId":39,"briefTitle":40,"officialTitle":41,"acronym":42,"eligibilityCriteria":43,"healthyVolunteers":44,"sex":45,"minAge":46,"maxAge":11,"enrollmentInfo":47,"targetDuration":11,"studyType":50,"phases":11,"briefSummary":51,"conditions":52,"keywords":54,"overallStatus":57,"whyStopped":11,"lastUpdateSubmitDate":58,"lastUpdatePostDateStruct":59,"startDateStruct":61,"completionDateStruct":63,"leadSponsor":65,"locationsCount":11},{"fullName":5,"class":6},"Aristotle University Of Thessaloniki","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":11},[9],{"measure":10,"description":11,"timeFrame":12},"Cardiovascular mortality",null,"10 years",[14],{"measure":15,"description":11,"timeFrame":12},"Hospitalization for CV events",{"allocation":11,"interventionModel":11,"interventionModelDescription":11,"primaryPurpose":11,"observationalModel":17,"timePerspective":18,"maskingInfo":11},"COHORT","PROSPECTIVE","Inclusion criteria\n\n* Age \\> 50 years volunteers (2 towns of 15000 residents one in the north and one in the south of Greece)\n* End points\n* 5-10 years cardiovascular morbidity and mortality\n\nMeasurements at baseline\n\n* Anthropometrics\n\n  * Age (M\\>55 years; W\\>65 years)\n  * Weight-height- BMI\n  * Abdominal obesity (Waist circumference\\>102 cm(M), \\>88cm (W) Family history\n  * Family history of premature CV disease (M at age\\\u003C55 years; W at age\\\u003C65 years)\n\nHistory\n\n* Smoking\n* Diabetes Mellitus,\n* Established Heart disease: myocardial infarction; angina; coronary revascularization; heart failure\n* Established renal disease \\[diabetic nephropathy; renal impairment (serum creatinine M\\>133, W\\>124 mmol\u002Fl); proteinuria (\\> 300 mg\u002F24 h)\\]\n* Cerebrovascular disease: ischaemic stroke; cerebral haemorrhage; transient ischaemic attack\n* Peripheral artery disease\n* Advanced retinopathy: haemorrhages or exudates, papilloedema\n* Treatment\n\nMeasurements\n\n* Measurements Blood pressure\n\n  * Clinic BP\n  * 24h ABPM\n  * Home BP\n\nHeart\n\n* Electrocardiographic LVH\n* Echocardiographic LVH\n\nVessels\n\n* Carotid wall thickening or plaque\n* Carotid-femoral pulse wave velocity\n* Ankle\u002Fbrachial BP index\n\nLipids or other risk factors\n\n* Total cholesterol, Tg, HDL, LDL\n* Plasma creatinine, estimated glomerular filtration rate\n* Fasting plasma glucose or postload plasma glucose\n* Microalbuminuria and albumin-creatinine ratio\n* Glucose tolerance test\n\n  * Follow up each 3 year with all the above measurements","Volunteers,community sample, residents of a certain town",[22],{"name":23,"affiliation":24,"role":25},"Vasilios Kotsis, Prof","AUTH","STUDY_CHAIR",[27],{"name":23,"role":28,"phone":29,"phoneExt":30,"email":31},"CONTACT","6974748860","+30","vkotsis@auth.gr",{"type":33,"investigatorFullName":34,"investigatorTitle":35,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"PRINCIPAL_INVESTIGATOR","Vasilios Kotsis","Prof. Med","100130931","factors-influencing-cardiovascular-prognosis-100130931",false,"NCT00973206","Factors Influencing Cardiovascular Prognosis","Factors Influencing Cardiovascular Prognosis in Hypertensive Patients (Pythia Study)","Pythia-GR","Inclusion Criteria:\n\n* All age \\>50 volunteers\n\nExclusion Criteria:\n\n* None",true,"ALL","50 Years",{"count":48,"type":49},5000,"ESTIMATED","OBSERVATIONAL","The purpose of this study is to identify risks for cardiovascular events in a follow up period of 10 years.",[53],"Cardiovascular Mortality",[55,56],"cardiovascular morbidity","mortality community study","NOT_YET_RECRUITING","2014-06-24",{"date":60,"type":49},"2014-06-25",{"date":62,"type":11},"2017-01",{"date":64,"type":49},"2027-01",{"name":5,"class":6}]