[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100648025":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":21,"locations":27,"responsibleParty":51,"collaborators":20,"id":54,"slug":55,"hasResults":56,"nctId":57,"briefTitle":58,"officialTitle":58,"acronym":59,"eligibilityCriteria":60,"healthyVolunteers":61,"sex":62,"minAge":63,"maxAge":64,"enrollmentInfo":65,"targetDuration":20,"studyType":68,"phases":69,"briefSummary":71,"conditions":72,"keywords":77,"overallStatus":30,"whyStopped":20,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":96},{"fullName":5,"class":6},"Fondazione Don Carlo Gnocchi ETS","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Patients receiving StimolIrpinia-supported cognitive rehabilitation","EXPERIMENTAL","Inpatients with severe acquired brain injury will receive six 30-minute sessions of cognitive rehabilitation activities supported by the StimolIrpinia multimedia repository, delivered three times per week for two weeks, in addition to routine comprehensive rehabilitation.",[13],"Behavioral: StimolIrpinia-supported cognitive rehabilitation activities",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"BEHAVIORAL","StimolIrpinia-supported cognitive rehabilitation activities","StimolIrpinia is a multimedia repository of autobiographical and territorially relevant stimuli from the Irpinia area, including images, videos, iconographic materials, cultural information, local landmarks, traditional foods, and links to virtual exploration tools. The repository is not a medical device and does not provide autonomous therapeutic, diagnostic, or decision-support functions.\n\nPatients will receive six 30-minute sessions over two weeks. During each session, the operator will select multimedia materials and exercises according to the patient's life experiences, familiarity with the Irpinia area, and cognitive profile. Activities may include memory exercises, language exercises, spatial orientation tasks, autobiographical memory stimulation, recognition tasks, and gnosic activities. All patients will continue their routine comprehensive rehabilitation program.",[9],null,[22],{"name":23,"role":24,"phone":25,"phoneExt":20,"email":26},"Alfonso Magliacano","CONTACT","393387389414","amagliacano@dongnocchi.it",[28],{"facility":29,"status":30,"city":31,"state":32,"zip":33,"country":34,"countryCode":35,"cosmosGeoPoint":36,"geoPoint":41,"contacts":42},"Polo Specialistico Riabilitativo Fondazione Don Gnocchi","RECRUITING","Sant'Angelo dei Lombardi","AV","83054","Italy","IT",{"type":37,"coordinates":38},"Point",[39,40],15.17535,40.92937,{"lat":40,"lon":39},[43,45,46,48],{"name":23,"role":24,"phone":44,"phoneExt":20,"email":26},"3387389414",{"name":20,"role":24,"phone":20,"phoneExt":20,"email":26},{"name":23,"role":47,"phone":20,"phoneExt":20,"email":20},"PRINCIPAL_INVESTIGATOR",{"name":49,"role":50,"phone":20,"phoneExt":20,"email":20},"Anna Estraneo","SUB_INVESTIGATOR",{"type":52,"investigatorFullName":23,"investigatorTitle":53,"investigatorAffiliation":5,"oldNameTitle":20,"oldOrganization":20},"SPONSOR_INVESTIGATOR","Researcher, Psychologist, PhD","100648025","feasibility-and-acceptability-of-stimolirpinia-for-cognitive-rehabilitation-after-severe-acquired-brain-injury-100648025",false,"NCT07718321","Feasibility and Acceptability of StimolIrpinia for Cognitive Rehabilitation After Severe Acquired Brain Injury","StimolIrpinia","Patients With Severe Acquired Brain Injury - Inclusion Criteria\n\n* Age between 18 and 75 years.\n* Level of Cognitive Functioning (LCF) score \\>= 5 at study entry.\n* Stable clinical diagnosis, assessed by at least four repeated LCF evaluations within a 1-week time window.\n* History of severe acquired brain injury of traumatic, anoxic, vascular, or mixed etiology, defined as Glasgow Coma Scale score \\\u003C= 8 for at least 24 hours after brain injury.\n* Pathological performance on at least one Oxford Cognitive Screening (OCS) subscale.\n* Having lived for a prolonged period in the Irpinia area, including Partenio, Valle Ufita-Baronia, Serinese-Solofrana, Alta Irpinia, Vallo di Lauro-Baianese, and\u002For Terminio-Cervialto.\n* Written informed consent signed by the patient or by the patient's legal representative.\n\nPatients With Severe Acquired Brain Injury - Exclusion Criteria • Severe medical conditions that may prevent participation in rehabilitation sessions, including severe language deficits incompatible with understanding instructions, severe cardiovascular instability, photosensitive or reflex epilepsy, and disabling visual or hearing deficits.\n\nRehabilitation Professionals\u002FOperators - Inclusion Criteria\n\n* Age \\>= 18 years.\n* Proven experience in neuromotor and\u002For cognitive rehabilitation of patients with severe acquired brain injury.\n* Written informed consent to participate in the study.\n\nRehabilitation Professionals\u002FOperators - Exclusion Criteria\n\n• Participation in the development of the StimolIrpinia repository, resulting in prior familiarity with the repository.",true,"ALL","18 Years","75 Years",{"count":66,"type":67},10,"ESTIMATED","INTERVENTIONAL",[70],"NA","This single-center pilot study evaluates the feasibility, acceptability, usability, and preliminary stimulus validation of StimolIrpinia, a multimedia repository of culturally and territorially relevant autobiographical stimuli designed to support cognitive rehabilitation activities in patients with severe acquired brain injury (sABI). The repository includes images, videos, maps, local cultural information, and printable materials related to the Irpinia area in Campania, Italy. Healthy adult volunteers will review the stimuli for their ability to evoke autobiographical memories, familiarity, emotional activation, and pleasantness. Hospitalized patients with sABI will complete six 30-minute StimolIrpinia-supported rehabilitation sessions over two weeks in addition to their routine comprehensive rehabilitation program. Rehabilitation professionals will receive standardized training and will use the repository to personalize cognitive rehabilitation exercises. Usability and acceptability will be evaluated from both patient and operator perspectives.",[73,74,75,76],"Severe Acquired Brain Injury","Cognitive Impairment","Cognitive Rehabilitation","Neurorehabilitation",[78,79,80,81,82,83,84,85,86],"severe acquired brain injury","cognitive rehabilitation","ecological rehabiliation","autobiographical stimuli","multimedia repository","acceptability","usability","feasibility","irpinia","2026-07-16",{"date":89,"type":90},"2026-07-21","ACTUAL",{"date":92,"type":90},"2026-06-22",{"date":94,"type":67},"2027-08-22",{"name":23,"class":6},1]