[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100366130":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":56,"centralContacts":61,"locations":67,"responsibleParty":85,"collaborators":87,"id":93,"slug":94,"hasResults":95,"nctId":96,"briefTitle":97,"officialTitle":98,"acronym":26,"eligibilityCriteria":99,"healthyVolunteers":95,"sex":100,"minAge":101,"maxAge":26,"enrollmentInfo":102,"targetDuration":26,"studyType":105,"phases":106,"briefSummary":108,"conditions":109,"keywords":26,"overallStatus":69,"whyStopped":26,"lastUpdateSubmitDate":113,"lastUpdatePostDateStruct":114,"startDateStruct":117,"completionDateStruct":119,"leadSponsor":121,"locationsCount":122},{"fullName":5,"class":6},"Mayo Clinic","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Cohort I (intra-operative microdialysis)","EXPERIMENTAL","Patients undergo microdialysis over 15 minutes during standard of care biopsy or resection. Patients also undergo MRI during screening and may undergo MRI on study.",[13,14],"Procedure: Microdialysis","Procedure: Magnetic Resonance Imaging",{"label":16,"type":10,"description":17,"interventionNames":18},"Cohort II (post-operative microdialysis)","Patients undergo microdialysis over 15 minutes after standard of care biopsy or resection. Patients also undergo MRI and CT on study.",[13,14,19],"Procedure: Computed Tomography",[21,27,42],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"PROCEDURE","Microdialysis","Undergo microdialysis",[9,16],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":31},"Magnetic Resonance Imaging","Undergo MRI",[9,16],[32,33,34,35,36,37,38,39,40,41],"Magnetic Resonance Imaging (MRI)","Magnetic Resonance Imaging Scan","Medical Imaging, Magnetic Resonance \u002F Nuclear Magnetic Resonance","MR","MR Imaging","NMR Imaging","Nuclear Magnetic Resonance Imaging (NMRI)","nuclear magnetic resonance imaging","sMRI","Structural MRI",{"type":22,"name":43,"description":44,"armGroupLabels":45,"otherNames":46},"Computed Tomography","Undergo CT",[16],[47,48,49,50,51,52,53,54,55],"CAT","CAT Scan","Computed Axial Tomography","computerized axial tomography","Computerized axial tomography (procedure)","computerized tomography","Computerized Tomography (CT) scan","CT","CT Scan",[57],{"name":58,"affiliation":59,"role":60},"Terence C Burns, MD, PhD","Mayo Clinic in Rochester","PRINCIPAL_INVESTIGATOR",[62],{"name":63,"role":64,"phone":65,"phoneExt":26,"email":66},"Clinical Trials Referral Office","CONTACT","855-776-0015","mayocliniccancerstudies@mayo.edu",[68],{"facility":59,"status":69,"city":70,"state":71,"zip":72,"country":73,"countryCode":74,"cosmosGeoPoint":75,"geoPoint":80,"contacts":81},"RECRUITING","Rochester","Minnesota","55905","United States","US",{"type":76,"coordinates":77},"Point",[78,79],-92.4699,44.02163,{"lat":79,"lon":78},[82,83],{"name":63,"role":64,"phone":65,"phoneExt":26,"email":66},{"name":84,"role":60,"phone":26,"phoneExt":26,"email":26},"Terence C. Burns, MD, PhD",{"type":86,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR",[88,91],{"name":89,"class":90},"National Cancer Institute (NCI)","NIH",{"name":92,"class":90},"National Institute of Neurological Disorders and Stroke (NINDS)","100366130","feasibility-of-intraoperative-microdialysis-during-neurosurgery-for-central-nervous-system-malignancies-100366130",false,"NCT04047264","Feasibility of Intra- and Post-operative Microdialysis During Neurosurgery for Central Nervous System Lesions","Intra- and Post-operative Microdialysis During Neurosurgery for Central Nervous System Lesions","Inclusion Criteria:\n\n* Age \\>= 18 years\n* Diagnosis of the following, based on clinical and radiographic evidence:\n\n  * Any glioma\n  * Metastatic brain tumor of any primary origin\n  * Epileptic focus requiring surgical resection\n* Planned neurosurgical procedure for purposes of biopsy or resection of suspected or previously diagnosed brain tumor (primary or metastatic) or epileptic focus as part of routine clinical care\n* Willing to undergo neurosurgical resection or biopsy at Mayo Clinic \\[Rochester, Minnesota (MN)\\]\n* For patients with gliomas recruited for post-operative microdialysis, willingness to stay in the hospital through post-operative day (POD) 3-5 (timing per physician and patient's shared decision making)\n* Ability to understand and the willingness to sign a written informed consent document\n* Enrollment into the Biobank study (IRB#12-003458)\n\nExclusion Criteria:\n\n* Vulnerable populations: pregnant women, prisoners or the mentally handicapped\n* Patients who are not appropriate candidates for surgery due to current or past medical history or uncontrolled concurrent illness","ALL","18 Years",{"count":103,"type":104},100,"ESTIMATED","INTERVENTIONAL",[107],"NA","This clinical trial evaluates the use of microdialysis catheters during surgery to collect biomarkers, and studies the feasibility of intra- and post-operative microdialysis during neurosurgery for central nervous system malignancies. A biomarker is a measurable indicator of the severity or presence of disease state. Information collected in this study may help doctors develop new strategies to better diagnose, monitor, and treat brain tumors.",[110,111,112],"Glioma","Glioblastoma","Metastatic Malignant Neoplasm in the Brain","2026-08-14",{"date":115,"type":116},"2026-08-18","ACTUAL",{"date":118,"type":116},"2020-01-01",{"date":120,"type":104},"2027-09-01",{"name":5,"class":6},1]