[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100649338":3},{"organization":4,"armGroups":7,"interventions":22,"overallOfficials":28,"centralContacts":29,"locations":35,"responsibleParty":56,"collaborators":28,"id":58,"slug":59,"hasResults":60,"nctId":61,"briefTitle":62,"officialTitle":63,"acronym":28,"eligibilityCriteria":64,"healthyVolunteers":60,"sex":65,"minAge":66,"maxAge":67,"enrollmentInfo":68,"targetDuration":28,"studyType":71,"phases":72,"briefSummary":74,"conditions":75,"keywords":78,"overallStatus":83,"whyStopped":28,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":93},{"fullName":5,"class":6},"Duke University","OTHER",[8,14,18],{"label":9,"type":10,"description":11,"interventionNames":12},"2-Week Baseline Duration","EXPERIMENTAL","baseline 0, 2 additional weeks of assessment, then 8 weeks of intervention",[13],"Behavioral: FlexED",{"label":15,"type":10,"description":16,"interventionNames":17},"4-Week Baseline Duration","baseline 0, 4 additional weeks of assessment, then 8 weeks of intervention",[13],{"label":19,"type":10,"description":20,"interventionNames":21},"6-Week Baseline Duration","baseline 0, 6 additional weeks of assessment, then 8 weeks of intervention",[13],[23],{"type":24,"name":25,"description":26,"armGroupLabels":27,"otherNames":28},"BEHAVIORAL","FlexED","Intervention consists of seven \\~ 20-minute sessions of a digital intervention based on Acceptance and Commitment Therapy (ACT). Participants learn skills of body image flexibility by following an avatar through a story line and completing interactive exercises.",[9,15,19],null,[30],{"name":31,"role":32,"phone":33,"phoneExt":28,"email":34},"Rhonda Merwin, PhD","CONTACT","919-681-7231","rhonda.merwin@duke.edu",[36],{"facility":5,"status":28,"city":37,"state":38,"zip":39,"country":40,"countryCode":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"Durham","North Carolina","27705","United States","US",{"type":43,"coordinates":44},"Point",[45,46],-78.89862,35.99403,{"lat":46,"lon":45},[49,53],{"name":50,"role":32,"phone":51,"phoneExt":28,"email":52},"Dottie Mayo","919-668-1935","dottie.mayo@duke.edu",{"name":54,"role":55,"phone":28,"phoneExt":28,"email":28},"Rhonda M Merwin, PhD","PRINCIPAL_INVESTIGATOR",{"type":57,"investigatorFullName":28,"investigatorTitle":28,"investigatorAffiliation":28,"oldNameTitle":28,"oldOrganization":28},"SPONSOR","100649338","flexed-full-threshold-ed-substudy-100649338",false,"NCT07732829","FlexED: Full Threshold ED Substudy","FlexED: A Digital Gamified Early Intervention for Eating Disorders","Inclusion Criteria:\n\n* Female age 15-25 years\n* Weight Concerns Scale score of \\>=47\n* Meets diagnostic criteria for an eating disorder based on the DSM-5\n\nExclusion Criteria:\n\n* Psychosis, substance use disorder, or current suicidal ideation or self-harm\n* Start or change in psychiatric medications within the past month\n* Non-English speaking","ALL","15 Years","25 Years",{"count":69,"type":70},6,"ESTIMATED","INTERVENTIONAL",[73],"NA","The purpose of this study is to test whether a new digital intervention decreases eating disorder symptoms in young women with eating disorders by changing how they experience thoughts and feelings about their body. The digital intervention is based on Acceptance and Commitment Therapy (ACT). Participants complete up to 7 digital intervention sessions using their mobile phone that include a character, story line and interactive exercises, games and digital rewards.\n\nResearchers will examine the impact of the intervention on participants' ability to respond flexibly to body-image distress or triggers, measuring things like heart rate, eye movements, and reaction time to body-image related words and images, and examine changes in eating disorder symptoms before and after intervention.",[76,77],"Eating Disorders","Body Image",[79,76,80,81,82],"Body Image Flexibility","Acceptance and Commitment Therapy","Psychological Flexibility","Early Intervention","NOT_YET_RECRUITING","2026-07-24",{"date":86,"type":87},"2026-07-29","ACTUAL",{"date":89,"type":70},"2026-07",{"date":91,"type":70},"2028-07",{"name":5,"class":6},1]