[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100650811":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":26,"centralContacts":31,"locations":36,"responsibleParty":56,"collaborators":23,"id":58,"slug":59,"hasResults":60,"nctId":61,"briefTitle":62,"officialTitle":63,"acronym":23,"eligibilityCriteria":64,"healthyVolunteers":60,"sex":65,"minAge":66,"maxAge":67,"enrollmentInfo":68,"targetDuration":23,"studyType":71,"phases":72,"briefSummary":74,"conditions":75,"keywords":77,"overallStatus":39,"whyStopped":23,"lastUpdateSubmitDate":81,"lastUpdatePostDateStruct":82,"startDateStruct":85,"completionDateStruct":87,"leadSponsor":89,"locationsCount":90},{"fullName":5,"class":6},"Al-Azhar University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Flexible Nephroscopy-Assisted Single-Tract PCNL","EXPERIMENTAL","Single-tract percutaneous nephrolithotomy using flexible nephroscopy through the same tract, with rigid nephroscopy, pneumatic lithotripsy, and Holmium:YAG laser as needed.",[13],"Procedure: Flexible Nephroscopy-Assisted Single-Tract PCNL",{"label":15,"type":10,"description":16,"interventionNames":17},"Conventional Multi-Tract PCNL","Multi-tract percutaneous nephrolithotomy using rigid nephroscopy through multiple accesses, with pneumatic lithotripsy as needed.",[18],"Procedure: Conventional Multi-Tract PCNL",[20,24],{"type":21,"name":9,"description":11,"armGroupLabels":22,"otherNames":23},"PROCEDURE",[9],null,{"type":21,"name":15,"description":16,"armGroupLabels":25,"otherNames":23},[15],[27],{"name":28,"affiliation":29,"role":30},"Abul-fotouh Ahmed","Department of Urology, Faculty of Medicine, Al-Azhar University, Cairo, Egypt","PRINCIPAL_INVESTIGATOR",[32],{"name":28,"role":33,"phone":34,"phoneExt":23,"email":35},"CONTACT","00201001066756","abulfotouhahmed7070@gmail.com",[37],{"facility":38,"status":39,"city":40,"state":23,"zip":23,"country":41,"countryCode":42,"cosmosGeoPoint":43,"geoPoint":48,"contacts":49},"Department of Urology, Al-Hussein and Sayed Galal University Hospitals, Al-Azhar University","RECRUITING","Cairo","Egypt","EG",{"type":44,"coordinates":45},"Point",[46,47],31.24967,30.06263,{"lat":47,"lon":46},[50,53],{"name":28,"role":33,"phone":51,"phoneExt":23,"email":52},"+201001066756","abulfotouhahmed@yahoo.com",{"name":54,"role":55,"phone":23,"phoneExt":23,"email":23},"Ahmed S Elasy","SUB_INVESTIGATOR",{"type":30,"investigatorFullName":28,"investigatorTitle":57,"investigatorAffiliation":5,"oldNameTitle":23,"oldOrganization":23},"Professor of Urology","100650811","flexible-nephroscopy-assisted-single-tract-versus-multi-tract-percutaneous-nephrolithotomy-for-complex-renal-stones-100650811",false,"NCT07753733","Flexible Nephroscopy-Assisted Single-Tract Versus Multi-Tract Percutaneous Nephrolithotomy for Complex Renal Stones","Flexible Nephroscopy-Assisted Single-Tract Versus Multi-Tract Percutaneous Nephrolithotomy for Complex Renal Stones: A Prospective, Randomized, Non-Inferiority Trial","Inclusion Criteria:\n\n* Age 18-70 years.\n\nUnilateral complex renal stones defined by one or more of the following: Guy's Stone Score III-IV, S.T.O.N.E. score ≥9, staghorn or partial staghorn calculus, or stones involving at least 3 calyces on NCCT.\n\nPreoperative expectation of multiple accesses by the surgeon.\n\nWritten informed consent.\n\nExclusion Criteria:\n\nSolitary kidney.\n\nUncorrected coagulopathy.\n\nActive urinary tract infection.\n\nASA grade IV or higher.\n\nPregnancy.\n\nPrevious ipsilateral PCNL or open renal surgery.\n\nStones less than 2 cm or simple calyceal stones.\n\nRefusal or inability to comply with follow-up.\n\n\\-","ALL","18 Years","70 Years",{"count":69,"type":70},470,"ESTIMATED","INTERVENTIONAL",[73],"NA","This randomized, parallel-group, non-inferiority trial will compare flexible nephroscopy-assisted single-tract percutaneous nephrolithotomy with conventional multi-tract percutaneous nephrolithotomy in patients with complex unilateral renal stones. The primary outcome is stone-free rate at 3 months, and secondary outcomes include operative time, fluoroscopy time, hemoglobin drop, transfusion rate, hospital stay, complications, need for auxiliary procedures, and cost-effectiveness.",[76],"Percutaneous Nephrolithotomy",[78,79,80],"Renal stones","Flexible Nephroscopy","Multi-tract","2026-08-16",{"date":83,"type":84},"2026-08-18","ACTUAL",{"date":86,"type":84},"2026-08-13",{"date":88,"type":70},"2028-08-30",{"name":5,"class":6},1]