[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100660002":3},{"organization":4,"outcomesModule":7,"designInfo":34,"detailedDescription":36,"studyPopulation":37,"armGroups":38,"interventions":44,"overallOfficials":33,"centralContacts":50,"locations":59,"responsibleParty":262,"collaborators":33,"id":264,"slug":265,"hasResults":266,"nctId":267,"briefTitle":268,"officialTitle":268,"acronym":269,"eligibilityCriteria":270,"healthyVolunteers":266,"sex":271,"minAge":272,"maxAge":33,"enrollmentInfo":273,"targetDuration":33,"studyType":276,"phases":33,"briefSummary":277,"conditions":278,"keywords":280,"overallStatus":286,"whyStopped":33,"lastUpdateSubmitDate":287,"lastUpdatePostDateStruct":288,"startDateStruct":291,"completionDateStruct":293,"leadSponsor":295,"locationsCount":296},{"fullName":5,"class":6},"University Hospital, Bordeaux","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":33},[9],{"measure":10,"description":11,"timeFrame":12},"Recurrence-free survival","Proportion of patients who remain free of oncological recurrence, either locoregional and\u002For metastatic, at 12 months after DSM.","12 months visit",[14,18,20,23,26,30],{"measure":15,"description":16,"timeFrame":17},"Post-adjuvant treatment mortality","Proportion of patients who have died from any cause at 1, 2, and 3 years after treatment.","12 months, 24 months and 36 months visits",{"measure":10,"description":19,"timeFrame":12},"Compare recurrence-free survival after local excision complicated by intraoperative perforation versus uncomplicated cases.",{"measure":21,"description":22,"timeFrame":12},"Adherence to oncological follow-up recommendations","Evaluate adherence to oncological follow-up recommendations proposed in multidisciplinary tumor board (MTB) meetings and\u002For by the operator.",{"measure":24,"description":25,"timeFrame":12},"Oncological risk factors","Evaluate oncological risk factors for lymph node and\u002For metastatic recurrence following local excision of a superficial colorectal cancer.",{"measure":27,"description":28,"timeFrame":29},"Healthcare resource utilization.","Compare healthcare resource utilization.","at 30 days, 3, 12, 24 and 36 months",{"measure":31,"description":32,"timeFrame":12},"New histo-prognostic risk factors","Investigate new histo-prognostic risk factors using molecular biology and proteomic profiling on submucosal dissection specimens.",null,{"allocation":33,"interventionModel":33,"interventionModelDescription":33,"primaryPurpose":33,"observationalModel":35,"timePerspective":6,"maskingInfo":33},"COHORT","French data from over 4,000 dissections (French Colorectal ESD Cohort in Experts Centers, FECCo, Clinical Trial NCT04592003) of LST (Lateral Spreading Tumor) or superficial colorectal cancer show reassuring results in terms of effectiveness with an 88% complete resection rate (R0) and safety with 1.2% of secondary surgery due to complications. Due to the absence of lymph node dissection compared to surgery, there is a theoretical risk of higher lymphatic recurrence with submucosal dissection. This study would allow for a better preoperative assessment of the benefit\u002Frisk ratio, as well as a more tailored therapeutic approach afterward based on the course of the resection and the analysis of the surgical specimen.","The study population will be drawn from the FECCo registry and will include patients who have undergone endoscopic resection using ESD, with final histological analysis confirming the presence of a colorectal cancer at high risk of lymph node recurrence.",[39],{"label":40,"type":33,"description":41,"interventionNames":42},"Surgery, Radiochimiotherapy, Surveillance","Patients who underwent surgery, radiochimiotherapy or nothing.",[43],"Procedure: Surgery, Radiochimiotherapy",[45],{"type":46,"name":47,"description":48,"armGroupLabels":49,"otherNames":33},"PROCEDURE","Surgery, Radiochimiotherapy","Analysis of medical data and residual biological samples",[40],[51,56],{"name":52,"role":53,"phone":54,"phoneExt":33,"email":55},"Arthur BERGER, MD","CONTACT","+335 56 79 56 79","arthur.berger@chu-bordeaux.fr",{"name":57,"role":53,"phone":33,"phoneExt":33,"email":58},"Francois TOQUER","francois.tocquer@chu-bordeaux.fr",[60,79,94,109,124,136,151,166,181,192,204,217,232,247],{"facility":61,"status":33,"city":62,"state":33,"zip":63,"country":64,"countryCode":65,"cosmosGeoPoint":66,"geoPoint":71,"contacts":72},"Clinique de l'Anjou","Angers","49000","France","FR",{"type":67,"coordinates":68},"Point",[69,70],-0.55202,47.47156,{"lat":70,"lon":69},[73,77],{"name":74,"role":53,"phone":75,"phoneExt":33,"email":76},"Edouard CHABRUN, MD","+33241241580","echabrun@gmail.com",{"name":74,"role":78,"phone":33,"phoneExt":33,"email":33},"PRINCIPAL_INVESTIGATOR",{"facility":80,"status":33,"city":81,"state":33,"zip":82,"country":64,"countryCode":65,"cosmosGeoPoint":83,"geoPoint":87,"contacts":88},"CHU Dijon Bourgogne","Dijon","21079",{"type":67,"coordinates":84},[85,86],5.01391,47.31344,{"lat":86,"lon":85},[89,93],{"name":90,"role":53,"phone":91,"phoneExt":33,"email":92},"Thibault DEGAND, MD","+33380293750","thibault.degand@chu-dijon.fr",{"name":90,"role":78,"phone":33,"phoneExt":33,"email":33},{"facility":95,"status":33,"city":96,"state":33,"zip":97,"country":64,"countryCode":65,"cosmosGeoPoint":98,"geoPoint":102,"contacts":103},"CHU de Limoges","Limoges","87042",{"type":67,"coordinates":99},[100,101],1.24759,45.83362,{"lat":101,"lon":100},[104,108],{"name":105,"role":53,"phone":106,"phoneExt":33,"email":107},"Jérémie JACQUES, PROF","+33555058772","jeremie.jacques@chu-limoges.fr",{"name":105,"role":78,"phone":33,"phoneExt":33,"email":33},{"facility":110,"status":33,"city":111,"state":33,"zip":112,"country":64,"countryCode":65,"cosmosGeoPoint":113,"geoPoint":117,"contacts":118},"Hospices civils de Lyon - Hôpital Edouard Herriot","Lyon","69003",{"type":67,"coordinates":114},[115,116],4.84789,45.74906,{"lat":116,"lon":115},[119,123],{"name":120,"role":53,"phone":121,"phoneExt":33,"email":122},"Mathieu PIOCHE, PROF","+33472110369","mathieu.pioche@chu-lyon.fr",{"name":120,"role":78,"phone":33,"phoneExt":33,"email":33},{"facility":125,"status":33,"city":111,"state":33,"zip":126,"country":64,"countryCode":65,"cosmosGeoPoint":127,"geoPoint":129,"contacts":130},"Clinique Jean Mermoz","69008",{"type":67,"coordinates":128},[115,116],{"lat":116,"lon":115},[131,135],{"name":132,"role":53,"phone":133,"phoneExt":33,"email":134},"Sarah LEBLANC, MD","+33478756743","sarahleblanc34@hotmail.com",{"name":132,"role":78,"phone":33,"phoneExt":33,"email":33},{"facility":137,"status":33,"city":138,"state":33,"zip":139,"country":64,"countryCode":65,"cosmosGeoPoint":140,"geoPoint":144,"contacts":145},"Clinique Jules Verne","Nantes","44300",{"type":67,"coordinates":141},[142,143],-1.55336,47.21725,{"lat":143,"lon":142},[146,150],{"name":147,"role":53,"phone":148,"phoneExt":33,"email":149},"Bertrand BRIEAU, MD","+33251173400","bertrand.brieau@gmail.com",{"name":147,"role":78,"phone":33,"phoneExt":33,"email":33},{"facility":152,"status":33,"city":153,"state":33,"zip":154,"country":64,"countryCode":65,"cosmosGeoPoint":155,"geoPoint":159,"contacts":160},"CHU Nîmes","Nîmes","30029",{"type":67,"coordinates":156},[157,158],4.35788,43.83665,{"lat":158,"lon":157},[161,165],{"name":162,"role":53,"phone":163,"phoneExt":33,"email":164},"Ludovic CAILLO, MD","+33466683183","ludovic.caillo@chu-nimes.fr",{"name":162,"role":78,"phone":33,"phoneExt":33,"email":33},{"facility":167,"status":33,"city":168,"state":33,"zip":169,"country":64,"countryCode":65,"cosmosGeoPoint":170,"geoPoint":174,"contacts":175},"AP-HP Hôpital Cochin","Paris","75014",{"type":67,"coordinates":171},[172,173],2.3488,48.85341,{"lat":173,"lon":172},[176,180],{"name":177,"role":53,"phone":178,"phoneExt":33,"email":179},"Arthur BELLE, MD","+33158414243","arthur.belle@aphp.fr",{"name":177,"role":78,"phone":33,"phoneExt":33,"email":33},{"facility":182,"status":33,"city":168,"state":33,"zip":169,"country":64,"countryCode":65,"cosmosGeoPoint":183,"geoPoint":185,"contacts":186},"Paris Saint Joseph",{"type":67,"coordinates":184},[172,173],{"lat":173,"lon":172},[187,191],{"name":188,"role":53,"phone":189,"phoneExt":33,"email":190},"Yann LE BALEUR, MD","+33144123009","ylebaleur@ghpsj.fr",{"name":188,"role":78,"phone":33,"phoneExt":33,"email":33},{"facility":193,"status":33,"city":168,"state":33,"zip":194,"country":64,"countryCode":65,"cosmosGeoPoint":195,"geoPoint":197,"contacts":198},"AP-HP Hôpital Européen Georges-Pompidou","75015",{"type":67,"coordinates":196},[172,173],{"lat":173,"lon":172},[199,203],{"name":200,"role":53,"phone":201,"phoneExt":33,"email":202},"Guillaume PERROD, MD","+33156095700","guillaume.perrod@aphp.fr",{"name":200,"role":78,"phone":33,"phoneExt":33,"email":33},{"facility":205,"status":33,"city":206,"state":33,"zip":207,"country":64,"countryCode":65,"cosmosGeoPoint":208,"geoPoint":212,"contacts":213},"CHU de Bordeaux","Pessac","33604",{"type":67,"coordinates":209},[210,211],-0.6324,44.80565,{"lat":211,"lon":210},[214,216],{"name":52,"role":53,"phone":215,"phoneExt":33,"email":55},"+33557656439",{"name":52,"role":78,"phone":33,"phoneExt":33,"email":33},{"facility":218,"status":33,"city":219,"state":33,"zip":220,"country":64,"countryCode":65,"cosmosGeoPoint":221,"geoPoint":225,"contacts":226},"CHU de Rennes","Rennes","35033",{"type":67,"coordinates":222},[223,224],-1.67431,48.11109,{"lat":224,"lon":223},[227,231],{"name":228,"role":53,"phone":229,"phoneExt":33,"email":230},"Timothée WALLENHORST, MD","+33299284321","timothee.wallenhorst@chu-rennes.fr",{"name":228,"role":78,"phone":33,"phoneExt":33,"email":33},{"facility":233,"status":33,"city":234,"state":33,"zip":235,"country":64,"countryCode":65,"cosmosGeoPoint":236,"geoPoint":240,"contacts":241},"Clinique Santé Atlantique","Saint-Herblain","44800",{"type":67,"coordinates":237},[238,239],-1.651,47.21154,{"lat":239,"lon":238},[242,246],{"name":243,"role":53,"phone":244,"phoneExt":33,"email":245},"Nicolas MUSQUER, MD","+33251724626","drnicolasmusquer@outlook.fr",{"name":243,"role":78,"phone":33,"phoneExt":33,"email":33},{"facility":248,"status":33,"city":249,"state":33,"zip":250,"country":64,"countryCode":65,"cosmosGeoPoint":251,"geoPoint":255,"contacts":256},"CHRU de Nancy","Vandœuvre-lès-Nancy","54511",{"type":67,"coordinates":252},[253,254],6.17114,48.66115,{"lat":254,"lon":253},[257,261],{"name":258,"role":53,"phone":259,"phoneExt":33,"email":260},"Marion SCHAEFER, MD","+33383154149","m.schaefer@chru-nancy.fr",{"name":258,"role":78,"phone":33,"phoneExt":33,"email":33},{"type":263,"investigatorFullName":33,"investigatorTitle":33,"investigatorAffiliation":33,"oldNameTitle":33,"oldOrganization":33},"SPONSOR","100660002","follow-up-after-oncological-resection-by-endoscopic-colorectal-esd-100660002",false,"NCT07871227","Follow-up After Oncological Resection by Endoscopic Colorectal ESD","FORCE","Inclusion Criteria:\n\n* Adult patient (18 years or older).\n* Presumed diagnosis of localized superficial colorectal cancer (T1) during endoscopy using the Conecct classification, confirmed by subsequent histopathological analysis.\n* Patient included in the FECCo registry since September 2019 for submucosal dissection.\n* Histological analysis of the resection specimen revealing a superficial colorectal adenocarcinoma with high risk of lymphatic recurrence, defined by at least one of the following criteria: submucosal invasion depth ≥ 1000 microns, tumor budding grade ≥ 2, presence of lymphatic and\u002For vascular emboli.\n\nExclusion Criteria:\n\n* History of Crohn's disease (ICD-10: K50) or ulcerative colitis (ICD-10: K51).\n* History of familial adenomatous polyposis and\u002For genetic predisposition to colorectal cancer (ICD-10: D12.6+0\u002F1\u002F2\u002F4\u002F5 and 6).\n* Malignant tumor of the colon staged ≥ T2.\n* Patients not included in the FECCo registry.\n* Documented objection through the non-opposition form following review of the information notice","ALL","18 Years",{"count":274,"type":275},1200,"ESTIMATED","OBSERVATIONAL","Colorectal cancer is a common and leading cause of death. Pre-cancerous lesions, as well as some so-called superficial cancers, can be resected via endoscopy. The technique chosen in the case of extensive lesions or superficial cancer is submucosal dissection. This technique helps avoid surgery, which has a higher morbidity and mortality (especially due to the non-preservation of the organ).",[279],"Colorectal Neoplasms",[281,282,283,284,285],"Rectal Cancer","Rectum Cancer","Submucosal dissection","Lymph node recurrence","Risk factors","NOT_YET_RECRUITING","2026-10-06",{"date":289,"type":290},"2026-10-13","ACTUAL",{"date":292,"type":275},"2026-10",{"date":294,"type":275},"2030-12",{"name":5,"class":6},14]