[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100657998":3},{"organization":4,"outcomesModule":7,"designInfo":30,"detailedDescription":33,"studyPopulation":34,"armGroups":35,"interventions":29,"overallOfficials":39,"centralContacts":44,"locations":29,"responsibleParty":50,"collaborators":29,"id":54,"slug":55,"hasResults":56,"nctId":57,"briefTitle":58,"officialTitle":59,"acronym":29,"eligibilityCriteria":60,"healthyVolunteers":56,"sex":61,"minAge":62,"maxAge":63,"enrollmentInfo":64,"targetDuration":29,"studyType":67,"phases":29,"briefSummary":68,"conditions":69,"keywords":72,"overallStatus":78,"whyStopped":29,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":83,"completionDateStruct":85,"leadSponsor":87,"locationsCount":29},{"fullName":5,"class":6},"Assiut University","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":29},[9],{"measure":10,"description":11,"timeFrame":12},"Mean gait velocity","Mean gait velocity in meters per second measured by quantitative spatiotemporal gait analysis.","Baseline",[14,17,20,23,26],{"measure":15,"description":16,"timeFrame":12},"Mean cadence","Mean cadence in steps per minute measured by quantitative gait analysis.",{"measure":18,"description":19,"timeFrame":12},"Mean stride length","Mean stride length in centimeters measured by quantitative gait analysis.",{"measure":21,"description":22,"timeFrame":12},"Mean MoCA score","Mean Montreal Cognitive Assessment (MoCA) score (range 0-30, higher scores indicate better cognition).",{"measure":24,"description":25,"timeFrame":12},"Mean P100 latency","Mean P100 latency in milliseconds measured by pattern-reversal visual evoked potentials.",{"measure":27,"description":28,"timeFrame":12},"Mean EDSS score","Mean Expanded Disability Status Scale (EDSS) score (range 0-10, higher scores indicate worse disability).",null,{"allocation":29,"interventionModel":29,"interventionModelDescription":29,"primaryPurpose":29,"observationalModel":31,"timePerspective":32,"maskingInfo":29},"CASE_ONLY","CROSS_SECTIONAL","Gait impairment is a common and disabling feature of multiple sclerosis. This observational study will include patients with confirmed multiple sclerosis according to the revised McDonald criteria who are clinically stable.\n\nParticipants will undergo quantitative gait analysis, cognitive assessment, visual evoked potential testing, and review of MRI findings in a single assessment visit.","Patients with multiple sclerosis attending the Neurology Department outpatient clinic and gait laboratory at Assiut University.",[36],{"label":37,"type":29,"description":38,"interventionNames":29},"Single cohort: Multiple Sclerosis Patients","Patients with confirmed multiple sclerosis who will undergo gait analysis, cognitive testing, visual evoked potential assessment, and MRI review in a single visit.",[40],{"name":41,"affiliation":42,"role":43},"Tarek A Rageh, prof","Neuropsychiatry Department, Assiut University Hospitals","STUDY_CHAIR",[45],{"name":46,"role":47,"phone":48,"phoneExt":29,"email":49},"Manar A Ali, Resident","CONTACT","01091423914","manarmoataz2000@gmail.com",{"type":51,"investigatorFullName":52,"investigatorTitle":53,"investigatorAffiliation":5,"oldNameTitle":29,"oldOrganization":29},"PRINCIPAL_INVESTIGATOR","Manar Moataz Abdel-ghani","Resident Physician, Department of Neuropsychiatry","100657998","gait-pattern-and-its-relation-to-cognition-and-vep-in-multiple-sclerosis-100657998",false,"NCT07847086","Gait Pattern and Its Relation to Cognition and VEP in Multiple Sclerosis","Pattern of Gait and Assessment Regarding Pathophysiology and Mechanism and Its Relation to Cognition, VEP, and Radiology as Prediction of Progression of Disease in Multiple Sclerosis Patients","Inclusion Criteria:\n\n* \\- Age 18 to 55 years\n* Confirmed diagnosis of multiple sclerosis according to the revised McDonald criteria\n* Clinically stable (no relapse or steroid treatment within 4 weeks)\n* Able to walk independently with or without a single assistive device\n* Written informed consent\n\nExclusion Criteria:\n\n* \\- Other neurological, orthopedic, visual, or vestibular conditions affecting gait\n* Severe cognitive impairment precluding valid testing\n* Pregnancy\n* MRI contraindications\n* Ocular disease unrelated to multiple sclerosis","ALL","18 Years","55 Years",{"count":65,"type":66},70,"ESTIMATED","OBSERVATIONAL","This cross-sectional study aims to assess the pattern of gait in patients with multiple sclerosis and to evaluate its relation to cognitive function, visual evoked potentials, and radiological findings.",[70,71],"Multiple Sclerosis","Gait Disorders, Neurologic",[73,74,75,76,77],"Visual evoked potentials","Multiple sclerosis","Gait analysis","Cognition","Assiut","NOT_YET_RECRUITING","2026-09-28",{"date":81,"type":82},"2026-10-01","ACTUAL",{"date":84,"type":66},"2026-09-26",{"date":86,"type":66},"2028-03-01",{"name":5,"class":6}]