[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100599645":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":28,"centralContacts":32,"locations":41,"responsibleParty":58,"collaborators":24,"id":60,"slug":61,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":64,"acronym":65,"eligibilityCriteria":66,"healthyVolunteers":67,"sex":68,"minAge":69,"maxAge":24,"enrollmentInfo":70,"targetDuration":24,"studyType":73,"phases":74,"briefSummary":76,"conditions":77,"keywords":80,"overallStatus":44,"whyStopped":24,"lastUpdateSubmitDate":86,"lastUpdatePostDateStruct":87,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":95},{"fullName":5,"class":6},"University of California, San Francisco","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Whole Milk-Skim Milk","EXPERIMENTAL","Participants randomized to the whole milk-skim milk treatment sequence will be instructed to limit their liquid milk consumption to only whole milk during the first two months of the study (Month 1-2), followed by only non-fat milk during the final two months of the study (Month 3-4). Using an N-of-1 strategy delivered by the National Institutes of Health (NIH)-funded, University of California, San Francisco (UCSF)-run Eureka platform utilizing a mobile smartphone-based application, subjects will be instructed weekly via app and text-based messaging on the type of liquid milk (whole or non-fat) to consume.",[13],"Behavioral: Whole Milk-Skim Milk",{"label":15,"type":10,"description":16,"interventionNames":17},"Skim Milk-Whole Milk","Participants randomized to the skim milk-whole milk treatment sequence will be instructed to limit their liquid milk consumption to only non-fat milk during the first two months of the study (Month 1-2), followed by only whole-fat milk during the final two months of the study (Month 3-4). Using an N-of-1 strategy delivered by the National Institutes of Health (NIH)-funded, University of California, San Francisco (UCSF)-run Eureka platform utilizing a mobile smartphone-based application, subjects will be instructed weekly via app and text-based messaging on the type of liquid milk (whole or non-fat) to consume.",[18],"Behavioral: Skim Milk-Whole Milk",[20,25],{"type":21,"name":9,"description":22,"armGroupLabels":23,"otherNames":24},"BEHAVIORAL","If randomized to the whole milk-skim milk treatment sequence, participants will be instructed to restrict their liquid milk consumption to only whole milk for the first 2 months and to only skim milk for the last 2 months of the enrollment period. Participants will receive weekly app and text-based message reminders of their randomization assignments.",[9],null,{"type":21,"name":15,"description":26,"armGroupLabels":27,"otherNames":24},"If randomized to the skim milk-whole milk treatment sequence, participants will be instructed to restrict their liquid milk consumption to only skim milk for the first 2 months and to only whole milk for the last 2 months of the enrollment period. Participants will receive weekly app and text-based message reminders of their randomization assignments.",[15],[29],{"name":30,"affiliation":5,"role":31},"Gregory M Marcus, MD, MAS","PRINCIPAL_INVESTIGATOR",[33,37],{"name":30,"role":34,"phone":35,"phoneExt":24,"email":36},"CONTACT","415-476-5706","greg.marcus@ucsf.edu",{"name":38,"role":34,"phone":39,"phoneExt":24,"email":40},"Bella Peña","415-502-3053","bella.pena@ucsf.edu",[42],{"facility":43,"status":44,"city":45,"state":46,"zip":47,"country":48,"countryCode":49,"cosmosGeoPoint":50,"geoPoint":55,"contacts":56},"UCSF Medical Center at Parnassus","RECRUITING","San Francisco","California","94143","United States","US",{"type":51,"coordinates":52},"Point",[53,54],-122.41942,37.77493,{"lat":54,"lon":53},[57],{"name":30,"role":34,"phone":35,"phoneExt":24,"email":36},{"type":59,"investigatorFullName":24,"investigatorTitle":24,"investigatorAffiliation":24,"oldNameTitle":24,"oldOrganization":24},"SPONSOR","100599645","gauging-outcomes-of-total-milk-ingestion-on-lipid-and-gcontrol-100599645",false,"NCT07087184","Gauging Outcomes of Total Milk Ingestion on Lipid and gControl","GOT MILC","Inclusion Criteria:\n\n* Are age ≥18 years\n* Have a smartphone\n* Are able to use the Eureka mobile application\n* Consume, on average, at least one cup of dairy milk daily, at least 5 days per week\n\nExclusion Criteria:\n\n* Non-English speaker\n* Are lactose intolerant\n* History of myocardial infarction\n* History of type I or type II diabetes\n* Familial hypercholesterolemia\n* Plan to change treatment for cholesterol\n* Unable to read or sign to provide informed consent",true,"ALL","18 Years",{"count":71,"type":72},110,"ESTIMATED","INTERVENTIONAL",[75],"NA","Atherosclerotic cardiovascular disease remains the leading cause of death for adults in the United States. The cardiovascular impact of milk consumption remains a matter of long-standing scientific debate. Current guidelines for Americans recommend three daily servings of fat-free or low-fat (1%) dairy over full-fat options due to concerns that saturated fat may increase cardiovascular risk. Yet, the literature does not consistently support non-fat dairy as superior to high-fat dairy for reducing cardiometabolic risk. Identifying the comparative health benefits of non-fat versus high-fat dairy milk would be immediately applicable to patients who seek cardiovascular care. In this randomized, case-crossover trial, the investigators seek to efficiently assess the association between high-fat versus non-fat dairy milk consumption and insulin resistance. Utilizing the Eureka Platform, participants will be randomized to limit their liquid milk consumption to whole milk followed by skim milk (or vice versa), measuring the effect of milk fat content on glycemic index and lipid profile.",[78,79],"Heart Diseases","Cardiovascular Disease",[79,81,82,83,84,85],"Milk Fat","Milk","Dairy Products","Insulin Resistance","Hyperlipidemia","2026-07-20",{"date":88,"type":89},"2026-07-22","ACTUAL",{"date":91,"type":89},"2025-07-24",{"date":93,"type":72},"2027-08",{"name":5,"class":6},1]