[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100510287":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":28,"centralContacts":40,"locations":46,"responsibleParty":153,"collaborators":155,"id":161,"slug":162,"hasResults":163,"nctId":164,"briefTitle":165,"officialTitle":165,"acronym":166,"eligibilityCriteria":167,"healthyVolunteers":163,"sex":168,"minAge":169,"maxAge":24,"enrollmentInfo":170,"targetDuration":24,"studyType":173,"phases":174,"briefSummary":176,"conditions":177,"keywords":179,"overallStatus":49,"whyStopped":24,"lastUpdateSubmitDate":185,"lastUpdatePostDateStruct":186,"startDateStruct":189,"completionDateStruct":191,"leadSponsor":193,"locationsCount":194},{"fullName":5,"class":6},"University of Pennsylvania","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Sulcus tube placement","ACTIVE_COMPARATOR","Glaucoma drainage device (GDD) implantation with tube placement in the ciliary 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GDD implantation for ciliary sulcus and AC tube\n* Age greater than or equal to 18 years old\n\nExclusion Criteria:\n\n* Preexisting corneal condition that would affect the corneal endothelium or previous corneal transplant\n* Presence or history of Cypass Micro-Stent\n* Previous GDD, Xen Gel Stent or Preserflo MicroShunt removed less than 6 months before surgery\n* Presence of GDD implantation, Xen Gel Stent, of Preserflo MicroShunt\n* Previous trabeculectomy and\u002For minimally invasive glaucoma surgery within the past 6 months\n* AC intraocular lens\n* Presence of nanophthalmos, uncontrolled uveitis, silicone oil, Sturge-Weber syndrome or other conditions associated with elevated episcleral venous pressure\n* Unwilling or unable to give consent, unwilling to accept randomization, or unable to return for scheduled protocol visits\n* No light perception vision in the study eye or fellow eye visual acuity \\\u003C 20\u002F200\n* Need for glaucoma surgery combined with other ocular procedures (i.e. corneal transplant, or retinal surgery) or anticipated need for additional ocular surgery","ALL","18 Years",{"count":171,"type":172},226,"ESTIMATED","INTERVENTIONAL",[175],"NA","Glaucoma Drainage Device and Endothelial Cell Loss Compare Trial (DECLARE) is a multi-center, outcome-masked, randomized clinical trial. The purpose of this study is to compare glaucoma drainage device implantation in the anterior chamber (front part of the eye) and sulcus (small space between iris and front chamber of the eye) in efforts to minimize cell loss in the eye.",[178],"Glaucoma",[180,181,182,183,184],"glaucoma","glaucoma drainage device","endothelial cell density","endothelial cell loss","intraocular pressure","2026-07-13",{"date":187,"type":188},"2026-07-14","ACTUAL",{"date":190,"type":188},"2023-07-11",{"date":192,"type":172},"2027-12",{"name":5,"class":6},8]