[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100514557":3},{"organization":4,"armGroups":7,"interventions":26,"overallOfficials":32,"centralContacts":33,"locations":43,"responsibleParty":64,"collaborators":66,"id":70,"slug":71,"hasResults":72,"nctId":73,"briefTitle":74,"officialTitle":75,"acronym":32,"eligibilityCriteria":76,"healthyVolunteers":77,"sex":78,"minAge":79,"maxAge":80,"enrollmentInfo":81,"targetDuration":32,"studyType":84,"phases":85,"briefSummary":87,"conditions":88,"keywords":90,"overallStatus":45,"whyStopped":32,"lastUpdateSubmitDate":98,"lastUpdatePostDateStruct":99,"startDateStruct":102,"completionDateStruct":104,"leadSponsor":106,"locationsCount":107},{"fullName":5,"class":6},"Arizona State University","OTHER",[8,14,18,22],{"label":9,"type":10,"description":11,"interventionNames":12},"Static weekly physical activity goal of 150 minutes\u002Fweek","EXPERIMENTAL","Participants will receive a physical activity action planning intervention and assigned a static weekly physical activity goal of 150 minutes\u002Fweek of moderate-intensity activity; action planning sessions will focus on the participant achieving this weekly goal.",[13],"Behavioral: Physical Activity",{"label":15,"type":10,"description":16,"interventionNames":17},"Incremental weekly physical activity goal increase","Participants will receive a physical activity action planning intervention and assigned a weekly physical activity goal that is 20% greater than the level of moderate-intensity physical activity performed the previous week; action planning sessions will focus on the participant achieving their assigned goal.",[13],{"label":19,"type":10,"description":20,"interventionNames":21},"Self-selected weekly physical activity goal","Participants will receive a physical activity action planning intervention and will self-select their own moderate-intensity physical activity goal each week; action planning sessions will focus on helping participants achieve their self-selected goal.",[13],{"label":23,"type":10,"description":24,"interventionNames":25},"No stated weekly physical activity goal (comparison group)","Participants will receive a physical activity action planning intervention that does not include explicitly stated physical activity goals to achieve.",[13],[27],{"type":28,"name":29,"description":30,"armGroupLabels":31,"otherNames":32},"BEHAVIORAL","Physical Activity","Theory-driven behavioral physical activity promotion intervention.",[15,23,19,9],null,[34,39],{"name":35,"role":36,"phone":37,"phoneExt":32,"email":38},"Rodney Joseph, PhD","CONTACT","602-496-0772","rodney.joseph@asu.edu",{"name":40,"role":36,"phone":41,"phoneExt":32,"email":42},"Molly Maxfield, PhD","602-496-2311","molly.maxfield@asu.edu",[44],{"facility":5,"status":45,"city":46,"state":47,"zip":48,"country":49,"countryCode":50,"cosmosGeoPoint":51,"geoPoint":56,"contacts":57},"RECRUITING","Phoenix","Arizona","85004","United States","US",{"type":52,"coordinates":53},"Point",[54,55],-112.07404,33.44838,{"lat":55,"lon":54},[58,60,63],{"name":59,"role":36,"phone":37,"phoneExt":32,"email":38},"Rodney P Joseph",{"name":61,"role":62,"phone":32,"phoneExt":32,"email":32},"Rodney P Joseph, PhD","PRINCIPAL_INVESTIGATOR",{"name":40,"role":62,"phone":32,"phoneExt":32,"email":32},{"type":65,"investigatorFullName":32,"investigatorTitle":32,"investigatorAffiliation":32,"oldNameTitle":32,"oldOrganization":32},"SPONSOR",[67],{"name":68,"class":69},"National Institute on Aging (NIA)","NIH","100514557","goal-setting-to-promote-physical-activity-adherence-in-midlife-adults-100514557",false,"NCT05980052","Goal Setting to Promote Physical Activity Adherence in Midlife Adults","Goal Setting to Promote Physical Activity Adherence in Midlife to Reduce Risk of Alzheimer's Disease and Related-Dementias: A Randomized Mechanistic Proof-Of-Concept Trial","Inclusion Criteria:\n\n* Aged 45 to 65 years\n* BMI between 30 kg\u002Fm2 to 50 kg\u002Fm2\n* Participants must weigh a minimum of 110 pounds\n* Engaging in 60 minutes or less of self-reported moderate-to-vigorous physical activity at screening (based on Exercise Vital Sign Questionnaire)\n* Self-reported ownership of a smartphone with an iOS or Android operating system (necessary for participants to track their activity using a Fitbit activity monitor)\n\nExclusion Criteria:\n\n* Endorsing an item on the Physical Activity Readiness Questionnaire (PAR-Q), unless a physician's note is provided\n* Resting blood pressure greater than 200\u002F110 mmHG as assessed at the baseline study assessment (unless a physician's note is provided)\n* Pregnant or planning to become pregnant in next 8-months (Phase 1) or 12 months (Phase 2)\n* Plans to relocate out of metropolitan Phoenix, Arizona area in the next 8-months (Phase 1) or 12 months (Phase 2)\n* Participation in another physical activity, nutrition or weight loss program at time of screening or at any time during the intervention\n* Individuals with mild cognitive impairment (MCI), as determined by either a self-report of receiving a diagnosis of MCI from a health care provider or as assessed by the Montreal Cognitive Assessment (MoCA) at the study orientation session. A score \\\u003C 26 is an exclusion criterion for US born participants. A score of \\\u003C23 is an exclusion for participants born outside of the US who completed their high school education in a country where English is not the primary language.\n* Being previously prescribed one of the 5 approved Alzheimer's medications, including: Donepezil (Aricept), Rivastigmine (Exelon), Galantamine (Razadyne), Memantine (Namenda), Memantine + Donepezil (Namzaric)\n* Score of 16 or higher on the Center for Epidemiological Studies-Depression Scale (CES-D)\n* Self-reported current diagnosis of major depression\n* Currently taking 2 or more ant-depression drugs\n* History of stroke\n* Incarcerated individuals (i.e., Prisoners)",true,"ALL","45 Years","65 Years",{"count":82,"type":83},144,"ESTIMATED","INTERVENTIONAL",[86],"NA","Engaging in regular physical activity during midlife is a key lifestyle behavior associated with reduced risk for Alzheimer's disease and related dementias (AD\u002FADRD). Yet nearly half of midlife adults (48%) do not meet national physical activity guidelines. The purpose of this mechanistic trial is to identify effective goal setting techniques to enhance psychosocial processes of self-regulation for the successful promotion of PA and adherence to national PA guidelines among midlife adults, with the long-term goal of reducing AD\u002FADRD risk",[29,89],"Exercise",[91,92,93,94,95,96,97],"exercise","physical activity","mild cognitive impairment","Alzheimer's disease","dementia","behavior change","midlife","2026-07-16",{"date":100,"type":101},"2026-07-17","ACTUAL",{"date":103,"type":101},"2023-07-17",{"date":105,"type":83},"2027-05-31",{"name":5,"class":6},1]