[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100642438":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":31,"locations":38,"responsibleParty":58,"collaborators":11,"id":60,"slug":61,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":65,"acronym":66,"eligibilityCriteria":67,"healthyVolunteers":62,"sex":68,"minAge":69,"maxAge":70,"enrollmentInfo":71,"targetDuration":11,"studyType":74,"phases":75,"briefSummary":77,"conditions":78,"keywords":81,"overallStatus":41,"whyStopped":11,"lastUpdateSubmitDate":88,"lastUpdatePostDateStruct":89,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":96,"locationsCount":97},{"fullName":5,"class":6},"Rennes University Hospital","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Patient","EXPERIMENTAL",null,[13],"Genetic: Non invasive prenatal test",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":11},"GENETIC","Non invasive prenatal test","cell free fetal DNA analysis",[9],[21,24,27,29],{"name":22,"affiliation":5,"role":23},"Marion Mercier, Md","STUDY_DIRECTOR",{"name":25,"affiliation":5,"role":26},"Vincent LAVOUE, Pr","STUDY_CHAIR",{"name":28,"affiliation":5,"role":26},"Sylvie JAILLARD",{"name":30,"affiliation":5,"role":26},"Erika LAUNAY",[32],{"name":33,"role":34,"phone":35,"phoneExt":36,"email":37},"Marie-Laure Gervais","CONTACT","299282555","+33","marie-laure.gervais@chu-rennes.fr",[39],{"facility":40,"status":41,"city":42,"state":11,"zip":11,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"CHU Rennes","RECRUITING","Rennes","France","FR",{"type":46,"coordinates":47},"Point",[48,49],-1.67431,48.11109,{"lat":49,"lon":48},[52,56],{"name":53,"role":34,"phone":54,"phoneExt":36,"email":55},"Marion Mercier","299284321","marion.mercier@chu-rennes.fr",{"name":22,"role":57,"phone":11,"phoneExt":11,"email":11},"PRINCIPAL_INVESTIGATOR",{"type":59,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR","100642438","grace---genetic-insights-into-early-pregnancy-loss-using-cell-free-fetal-dna-100642438",false,"NCT07639333","GRACE - Genetic Insights Into Early pRegnancy Loss Using Cell-free fEtal DNA","GRACE - Genetic Insights Into Early pRegnancy Loss: A Prospective Study Using Cell-free fEtal DNA","GRACE","Inclusion Criteria:\n\n* A stopped pregnancy with an intrauterine pregnancy diagnosed by ultrasound (embryo larger than 7 mm corresponding to a gestational age of 6 weeks and 5 days. This is justified by the fact that fetal fragment (FF) detection is possible at 5 weeks of gestation, or 7 weeks and 5 days)\n* Expulsion of a pregnancy within the last 2 hours\n\n  * Patient fluent in French\n  * Enrolled in a social security program\n  * Has received oral and written information about the protocol and has signed a consent form to participate in this research.\n\nExclusion Criteria:\n\n* Diagnosis of an empty gestational sac, ectopic pregnancy, or unknown location\n* Ultrasound findings consistent with a molar pregnancy\n* Identified cause (preimplantation diagnosis, multiple uterine fibroids or a single fibroid \\> 5 cm, uterine malformation affecting the uterine cavity, lupus, and antiphospholipid syndrome)\n* Inability to obtain a blood sample\n* Known current malignant tumor\n* Blood transfusions within the last 3 months\n* Cell therapy or immunotherapy within the last 3 months\n* Previous organ transplant","FEMALE","18 Years","43 Years",{"count":72,"type":73},100,"ESTIMATED","INTERVENTIONAL",[76],"NA","The aim of this study is to assess the impact of non-invasive prenatal testing right after an early isolated miscarriage on mental health and on the patient's subsequent care in the year following the miscarriage",[79,80],"Miscarriage in First Trimester","Prenatal Genetic Diagnosis",[82,83,84,85,86,87],"early miscarriage","miscarriage","prenatal diagnosis","prenatal test","cell free fetal DNA","chromosomal abnomarlities","2026-07-13",{"date":90,"type":91},"2026-07-15","ACTUAL",{"date":93,"type":73},"2026-09",{"date":95,"type":73},"2029-01",{"name":5,"class":6},1]