[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100604527":3},{"organization":4,"armGroups":7,"interventions":13,"overallOfficials":10,"centralContacts":18,"locations":10,"responsibleParty":28,"collaborators":10,"id":30,"slug":31,"hasResults":32,"nctId":33,"briefTitle":34,"officialTitle":35,"acronym":36,"eligibilityCriteria":37,"healthyVolunteers":32,"sex":38,"minAge":10,"maxAge":39,"enrollmentInfo":40,"targetDuration":43,"studyType":44,"phases":10,"briefSummary":45,"conditions":46,"keywords":10,"overallStatus":49,"whyStopped":10,"lastUpdateSubmitDate":50,"lastUpdatePostDateStruct":51,"startDateStruct":54,"completionDateStruct":56,"leadSponsor":58,"locationsCount":10},{"fullName":5,"class":6},"Assistance Publique - Hôpitaux de Paris","OTHER",[8],{"label":9,"type":10,"description":10,"interventionNames":11},"All children\u002Fyoung adults (\u003C25 years old) with LAM diagnosed in participating French centers",null,[12],"Other: Long term follow-up",[14],{"type":6,"name":15,"description":16,"armGroupLabels":17,"otherNames":10},"Long term follow-up","Long term follow-up as part of standard of care",[9],[19,25],{"name":20,"role":21,"phone":22,"phoneExt":23,"email":24},"Arnaud Petit, MD PhD","CONTACT","+33 1 44 73 63 46","+33","arnaud.petit@aphp.fr",{"name":26,"role":21,"phone":10,"phoneExt":23,"email":27},"Jérôme Lambert, MD PhD","jerome.lambert@u-paris.fr",{"type":29,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100604527","harmonized-clinical-and-biological-database-for-integrated-research-into-the-management-of-pediatric-acute-myeloid-leukemia-100604527",false,"NCT07150676","Harmonized Clinical and Biological Database for Integrated Research Into the Management of Pediatric Acute Myeloid Leukemia","Base de DOnnées Cliniques et Biologiques harmonisées Pour Une REcherche intégrée à la Prise en Charge Des leucémies aiguës Myéloïdes pédiatriques","DOREMy","All patients under the age of 25 diagnosed with AML in the participating centers in France.","ALL","25 Years",{"count":41,"type":42},2000,"ESTIMATED","27 Years","OBSERVATIONAL","The aim of this project is to study the different diagnostic, predictive, and prognostic profiles, as well as their interrelationships (clinical, biological, genetic) in children with Acute Myeloid Leukemia (AML). Despite numerous research projects on separate cohorts, the prognosis for pediatric AML has not improved.\n\nThe project therefore consists of pooling research data and existing clinical and biological data from healthcare in a health data warehouse to increase its power.\n\nAs these diseases are rare and genetic subgroups even rarer, it is crucial to combine all these data sets into a single database to statistically validate our observations.\n\nThe ultimate goal of this project is to reduce the relapse rate and improve the survival rate of pediatric AML by identifying rare, uncharacterized patient subgroups at high risk of relapse, for whom clinical characteristics and outcomes will be compared with omics data, Leukemia Stem Cells signatures, and drug responses to establish accurate and in-depth profiles.",[47,48],"Acute Myeloid Leukemia (AML)","Pediatric Acute Myeloid Leukemia","NOT_YET_RECRUITING","2025-08-25",{"date":52,"type":53},"2025-09-02","ACTUAL",{"date":55,"type":42},"2025-10-01",{"date":57,"type":42},"2052-10-01",{"name":5,"class":6}]