[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100587417":3},{"organization":4,"armGroups":7,"interventions":26,"overallOfficials":41,"centralContacts":45,"locations":50,"responsibleParty":67,"collaborators":69,"id":73,"slug":74,"hasResults":75,"nctId":76,"briefTitle":77,"officialTitle":78,"acronym":79,"eligibilityCriteria":80,"healthyVolunteers":75,"sex":81,"minAge":82,"maxAge":83,"enrollmentInfo":84,"targetDuration":32,"studyType":87,"phases":88,"briefSummary":90,"conditions":91,"keywords":93,"overallStatus":53,"whyStopped":32,"lastUpdateSubmitDate":96,"lastUpdatePostDateStruct":97,"startDateStruct":100,"completionDateStruct":102,"leadSponsor":104,"locationsCount":105},{"fullName":5,"class":6},"University of Nebraska","OTHER",[8,14,20],{"label":9,"type":10,"description":11,"interventionNames":12},"Heat Therapy","EXPERIMENTAL","At home heat therapy 5 times (40-55 min) per week for 8 weeks.",[13],"Behavioral: Heat therapy",{"label":15,"type":16,"description":17,"interventionNames":18},"Control Therapy","SHAM_COMPARATOR","Sham at home thermoneutral therapy 5 times (40-55 min) per week for 8 weeks.",[19],"Behavioral: Sham Control",{"label":21,"type":22,"description":23,"interventionNames":24},"Walking Intervention Using Wearable Technology","ACTIVE_COMPARATOR","+1,500-3000 steps per day 3-5 days a week for 8 weeks.",[25],"Behavioral: Walking",[27,33,37],{"type":28,"name":29,"description":30,"armGroupLabels":31,"otherNames":32},"BEHAVIORAL","Heat therapy","At home lower body heat therapy",[9],null,{"type":28,"name":34,"description":35,"armGroupLabels":36,"otherNames":32},"Sham Control","Sham Thermoneutral",[15],{"type":28,"name":38,"description":39,"armGroupLabels":40,"otherNames":32},"Walking","Walking intervention",[21],[42],{"name":43,"affiliation":5,"role":44},"Gwenael Layec, PhD","PRINCIPAL_INVESTIGATOR",[46],{"name":43,"role":47,"phone":48,"phoneExt":32,"email":49},"CONTACT","402-554-3779","unovrl@unomaha.edu",[51],{"facility":52,"status":53,"city":54,"state":55,"zip":56,"country":57,"countryCode":58,"cosmosGeoPoint":59,"geoPoint":64,"contacts":65},"University of Nebraska Omaha","RECRUITING","Omaha","Nebraska","68182","United States","US",{"type":60,"coordinates":61},"Point",[62,63],-95.94043,41.25626,{"lat":63,"lon":62},[66],{"name":43,"role":47,"phone":48,"phoneExt":32,"email":49},{"type":68,"investigatorFullName":32,"investigatorTitle":32,"investigatorAffiliation":32,"oldNameTitle":32,"oldOrganization":32},"SPONSOR",[70],{"name":71,"class":72},"National Institute on Aging (NIA)","NIH","100587417","heat-therapy-and-mobility-in-covid-19-survivors-100587417",false,"NCT06928116","Heat thErapy And mobiLity in COVID-19 Survivors","Physical Rehabilitation of Long COVID by Heat Therapy","HEAL","Inclusion Criteria:\n\n* Between the ages of 50 and 90 years\n* Free from orthopedic limitations that would prohibit performing leg exercise\n* BMI \\\u003C 40 kg\u002Fm2 and weigh \\\u003C 400lbs\n* Previously contracted Covid-19 and have persistent symptoms such as a fatigue or decline in physical function, for at least 2 months following SARS-CoV-2 infection\n\nExclusion Criteria:\n\n* Unable to give written informed consent\n* Women who are pregnant, breastfeeding, or likely to become pregnant within the next 6 months\n* Women who are taking hormone therapy\n* Claustrophobia\n* Orthopedic limitations that would prohibit them from walking\n* Currently enrolled in an exercise-based or respiratory muscle rehabilitation program.","ALL","50 Years","90 Years",{"count":85,"type":86},99,"ESTIMATED","INTERVENTIONAL",[89],"NA","Post-acute sequelae of SARS-CoV-2 infection (PASC) is becoming a major risk factor for chronic diseases, with older adults and those with underlying health conditions at risk of developing persistent mobility limitations and disabilities. Although exercise intervention is a common strategy to restore functional capacity, it may not be feasible or enticing to many people with PASC. This clinical trial seeks to establish the tolerability and efficacy of at home lower-body heat therapy for improving functional capacity along with metabolic and vascular health in late-middle aged and older adults with PASC, also known as \"long COVID\".",[92],"Long COVID",[9,94,95],"mobility limitations","Post-acute sequelae of SARS-CoV-2 infection (PASC)","2026-07-15",{"date":98,"type":99},"2026-07-17","ACTUAL",{"date":101,"type":99},"2025-01-16",{"date":103,"type":86},"2029-08",{"name":5,"class":6},1]