[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100647169":3},{"organization":4,"armGroups":7,"interventions":21,"overallOfficials":36,"centralContacts":40,"locations":46,"responsibleParty":59,"collaborators":27,"id":61,"slug":62,"hasResults":63,"nctId":64,"briefTitle":65,"officialTitle":66,"acronym":27,"eligibilityCriteria":67,"healthyVolunteers":63,"sex":68,"minAge":69,"maxAge":70,"enrollmentInfo":71,"targetDuration":27,"studyType":74,"phases":75,"briefSummary":77,"conditions":78,"keywords":83,"overallStatus":90,"whyStopped":27,"lastUpdateSubmitDate":91,"lastUpdatePostDateStruct":92,"startDateStruct":95,"completionDateStruct":97,"leadSponsor":99,"locationsCount":100},{"fullName":5,"class":6},"Gaziler Physical Medicine and Rehabilitation Education and Research Hospital","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Active PMS plus Therapeutic Exercise","EXPERIMENTAL","Participants receive high-intensity peripheral magnetic stimulation (PMS) applied over the injured peripheral nerve using a predefined neuropathy protocol (approximately 10 minutes per session, variable frequencies 1-60 Hz), for a total of 9 sessions over 3 weeks (3 sessions per week). Stimulation intensity is increased until motor activity is elicited and kept constant during the session. In addition, participants receive a standardized therapeutic exercise program (active range of motion, strengthening, stretching, proprioception and balance exercises, and occupational therapy) for 20 minutes per day, 5 days per week, over 3 weeks.",[13,14],"Device: High-Intensity Peripheral Magnetic Stimulation","Other: Therapeutic Exercise Program",{"label":16,"type":17,"description":18,"interventionNames":19},"Sham PMS plus Therapeutic Exercise","SHAM_COMPARATOR","Participants receive sham peripheral magnetic stimulation using the same device, session duration, and application site, but with the applicator coil reversed to prevent effective delivery of the magnetic field to the target tissue. Device screen and audible feedback are maintained to preserve blinding. In addition, participants receive the same standardized therapeutic exercise program (active range of motion, strengthening, stretching, proprioception and balance exercises, and occupational therapy) for 20 minutes per day, 5 days per week, over 3 weeks.",[20,14],"Device: Sham Peripheral Magnetic Stimulation",[22,28,32],{"type":23,"name":24,"description":25,"armGroupLabels":26,"otherNames":27},"DEVICE","High-Intensity Peripheral Magnetic Stimulation","High-intensity peripheral magnetic stimulation delivered via an inductive coil placed over the injured peripheral nerve, using a predefined neuropathy protocol (approximately 10 minutes per session, variable frequencies 1-60 Hz). Stimulation intensity is increased until motor activity is elicited and kept constant during the session. Applied 3 times per week for 3 weeks (9 sessions total).",[9],null,{"type":23,"name":29,"description":30,"armGroupLabels":31,"otherNames":27},"Sham Peripheral Magnetic Stimulation","Sham peripheral magnetic stimulation using the same device, session duration, and application site, with the applicator coil reversed to prevent effective delivery of the magnetic field to the target tissue. Device screen and audible feedback are maintained to preserve blinding. Applied 3 times per week for 3 weeks (9 sessions total).",[16],{"type":6,"name":33,"description":34,"armGroupLabels":35,"otherNames":27},"Therapeutic Exercise Program","Standardized individualized therapeutic exercise program including active range of motion exercises, strengthening exercises, stretching exercises, proprioception and balance exercises, and occupational therapy for activities of daily living. Delivered for 20 minutes per day, 5 days per week, over 3 weeks.",[9,16],[37],{"name":38,"affiliation":5,"role":39},"Nurdan Korkmaz","PRINCIPAL_INVESTIGATOR",[41],{"name":42,"role":43,"phone":44,"phoneExt":27,"email":45},"Hüseyin Anıl İnan, MD","CONTACT","+905346159274","dranilinan@gmail.com",[47],{"facility":5,"status":27,"city":48,"state":27,"zip":49,"country":50,"countryCode":27,"cosmosGeoPoint":51,"geoPoint":56,"contacts":57},"Ankara","06800","Turkey (Türkiye)",{"type":52,"coordinates":53},"Point",[54,55],32.85427,39.91987,{"lat":55,"lon":54},[58],{"name":42,"role":43,"phone":44,"phoneExt":27,"email":45},{"type":39,"investigatorFullName":38,"investigatorTitle":60,"investigatorAffiliation":5,"oldNameTitle":27,"oldOrganization":27},"Associate Professor","100647169","high-intensity-peripheral-magnetic-stimulation-in-traumatic-peripheral-nerve-injury-100647169",false,"NCT07705490","High-Intensity Peripheral Magnetic Stimulation in Traumatic Peripheral Nerve Injury","Clinical and Electrophysiological Evaluation of the Effect of High-Intensity Peripheral Magnetic Stimulation in Traumatic Peripheral Nerve Injury: A Randomized, Double-Blind, Sham-Controlled Trial","Inclusion Criteria:\n\n* Age between 18 and 65 years\n* Traumatic peripheral nerve injury\n* Unilateral traumatic peripheral neuropathy confirmed by electromyography (EMG)\n* Nerve injury occurring at least 3 months prior\n* Douleur Neuropathique 4 (DN4) score ≥ 4\n* Visual Analog Scale (VAS) score ≥ 4\n* Manual Muscle Testing score \\\u003C 5\n* No analgesic use, or stable analgesic therapy for the past month (no dose changes)\n\nExclusion Criteria:\n\n* Active infection or malignancy\n* Metal implant or shrapnel in the application area\n* Electronic implants (e.g., cardiac pacemaker, spinal cord stimulator, deep brain stimulator)\n* Central nervous system diseases\n* Non-traumatic causes of neuropathy (e.g., radiculopathy, diabetic neuropathy, entrapment neuropathies, HIV-related neuropathy, trigeminal neuralgia)\n* Complete nerve injury\n* Injury involving three or more peripheral nerves or plexus injury\n* History of peripheral nerve surgery or injection within the past 3 months\n* Active psychiatric illness\n* Coagulopathy","ALL","18 Years","65 Years",{"count":72,"type":73},40,"ESTIMATED","INTERVENTIONAL",[76],"NA","Traumatic peripheral nerve injury is a common cause of chronic neuropathic pain, muscle weakness, and functional limitation, particularly in young and active individuals. Current conservative and pharmacological treatments often provide incomplete relief or carry side effects. High-intensity peripheral magnetic stimulation (PMS) is a non-invasive method that may help reduce neuropathic pain and support motor recovery, but evidence in traumatic nerve injury is limited.\n\nThis randomized, double-blind, sham-controlled trial aims to evaluate whether high-intensity PMS, added to a standardized therapeutic exercise program, improves pain, function, quality of life, and electrophysiological measures in adults with traumatic peripheral nerve injury. Participants will be randomly assigned to receive either active PMS or sham PMS, in addition to the same exercise program. Outcomes will be assessed at baseline, 4 weeks, and 8 weeks.",[79,80,81,82],"Peripheral Nerve Injuries","Traumatic Peripheral Nerve Injury","Neuropathic Pain","Peripheral Nerve Injuries, Traumatic",[84,85,81,86,87,88,89],"Peripheral Magnetic Stimulation","High-Intensity Magnetic Stimulation","Nerve Injury","Rehabilitation","Electrophysiology","Sham-Controlled Trial","NOT_YET_RECRUITING","2026-07-13",{"date":93,"type":94},"2026-07-15","ACTUAL",{"date":96,"type":73},"2026-08",{"date":98,"type":73},"2027-07",{"name":5,"class":6},1]