[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100419595":3},{"organization":4,"outcomesModule":7,"designInfo":101,"detailedDescription":104,"studyPopulation":104,"armGroups":110,"interventions":121,"overallOfficials":125,"centralContacts":138,"locations":145,"responsibleParty":1224,"collaborators":1226,"id":1233,"slug":1234,"hasResults":1235,"nctId":1236,"briefTitle":1237,"officialTitle":1238,"acronym":1239,"eligibilityCriteria":1240,"healthyVolunteers":1235,"sex":1241,"minAge":1242,"maxAge":104,"enrollmentInfo":1243,"targetDuration":104,"studyType":1246,"phases":1247,"briefSummary":1249,"conditions":1250,"keywords":104,"overallStatus":374,"whyStopped":104,"lastUpdateSubmitDate":1253,"lastUpdatePostDateStruct":1254,"startDateStruct":1257,"completionDateStruct":1259,"leadSponsor":1261,"locationsCount":1262},{"fullName":5,"class":6},"Population Health Research Institute","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":45},[9],{"measure":10,"description":11,"timeFrame":12},"All cause mortality","Death due to all causes","Within 90 days post randomization",[14,17,20,23,26,29,32,35,38,42],{"measure":15,"description":16,"timeFrame":12},"Ability to independently walk 3 meters","Ability to independently walk 3 meters (10 feet) or across a room without human assistance. Patients who require a cane or walker, but not human assistance, will be classified as able to walk independently. Patients who require assistance to get out of a chair, but can walk independently once they get up, will be classified as able to walk independently.",{"measure":18,"description":19,"timeFrame":12},"Composite of major complications","Composite includes vascular and nonvascular mortality, non-fatal myocardial infarction, acute congestive heart failure, and stroke.",{"measure":21,"description":22,"timeFrame":12},"Vascular mortality","Any death with a vascular cause and includes those deaths following a myocardial infarction, sudden cardiac arrest, stroke, cardiac revascularization procedure (i.e., percutaneous coronary intervention \\[PCI\\] or coronary artery bypass graft \\[CABG\\] surgery), heart failure, pulmonary embolus, cardiovascular hemorrhage, or deaths due to an unknown cause",{"measure":24,"description":25,"timeFrame":12},"Nonvascular mortality","Any death due to a clearly documented non-vascular cause.",{"measure":27,"description":28,"timeFrame":12},"Myocardial Infarction","Diagnosis of MI according to 4th universal definition of myocardial infarction",{"measure":30,"description":31,"timeFrame":12},"Acute Congestive Heart Failure","at least one clinical sign(s) or symptom(s) (e.g elevated jugular venous pressure, respiratory rales\u002Fcrackles, crepitations, hypoxia, tachypnea or presence of S3) with at least one of the following:\n\n1. radiographic findings (i.e., vascular redistribution, interstitial pulmonary edema, or frank alveolar pulmonary edema) or point of care ultrasound findings (i.e., bilateral B-lines, bilateral pleural effusion, elevated jugular venous pressure, dilated inferior vena cava with respiratory variation less than 50%) OR\n2. heart failure treatment implemented with diuretics with documented clinical improvement.",{"measure":33,"description":34,"timeFrame":12},"Stroke","Either - 1. a new focal neurological deficit thought to be vascular in origin with signs or symptoms lasting more than 24 hours or leading to death; or 2. a new focal neurological deficit thought to be vascular in origin with signs or symptoms lasting less 24 hours with a positive neuroimaging consistent with a stroke",{"measure":36,"description":37,"timeFrame":12},"Time from randomization to hospital discharge","Length of hospital stay from randomization to hospital discharge",{"measure":39,"description":40,"timeFrame":41},"Delirium","1. Patient meets the criteria for delirium on any in-person 3D-CAM or CAM administered; OR\n2. Positive history of delirium in the 7 days after randomization based on the review of hospital health records.","Within 7 days and 90 days post randomization",{"measure":43,"description":44,"timeFrame":41},"Moderate to severe pain","Moderate to severe pain is defined as any pain score ≥3 on 10 points scale.",[46,49,52,55,58,61,64,67,70,73,76,79,82,85,88,91,94,96,98],{"measure":47,"description":48,"timeFrame":12},"New clinically important atrial fibrillation or flutter","Documentation of atrial fibrillation or atrial flutter of any duration on an ECG, telemetry tracing, or rhythm strip and results in angina, congestive heart failure, symptomatic hypotension, or is followed by initiation or a dose increase of a rate controlling drug, antiarrhythmic drug, or electrical cardioversion.",{"measure":50,"description":51,"timeFrame":12},"Cardiac revascularization procedure","Revascularization procedures including coronary artery bypass graft or percutaneous coronary intervention surgery.",{"measure":53,"description":54,"timeFrame":12},"Venous thromboembolism","Venous pulmonary embolism or deep venous thrombosis",{"measure":56,"description":57,"timeFrame":12},"Pulmonary embolism","The diagnosis of PE requires any one of the following:\n\n1. A high probability ventilation\u002Fperfusion lung scan,\n2. An intraluminal filling defect of a segmental or larger artery on a helical CT scan,\n3. An intraluminal filling defect on pulmonary angiography, or\n4. A positive diagnostic test for DVT (e.g., positive compression ultrasound) and one of the following:\n\nA. Non-diagnostic (i.e., low or intermediate probability) ventilation\u002Fperfusion lung scan B. Non-diagnostic (i.e., subsegmental defects or technically inadequate study) helical CT scan.",{"measure":59,"description":60,"timeFrame":12},"Proximal deep venous thrombosis","The diagnosis of proximal DVT requires:\n\n1. Thrombosis involving the popliteal vein or more proximal veins for leg DVT and axillary or more proximal veins for arm DVT, AND\n2. Evidence of vein thrombosis by any one of the following:\n\n1\\. A persistent intraluminal filling defect on contrast venography, 2. Noncompressibility of one or more venous segments on B mode compression ultrasonography, or 3. A clearly defined intraluminal filling defect on contrast enhanced computed tomography.",{"measure":62,"description":63,"timeFrame":12},"Infection","Pathologic process caused by the invasion of normally sterile tissue or fluid or body cavity by pathogenic or potentially pathogenic organisms.",{"measure":65,"description":66,"timeFrame":12},"Sepsis","Based on the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3) criteria,20 sepsis will require a quick Sequential Organ Failure Assessment (qSOFA) Score ≥2 points or patients requiring vasopressors\u002Finotropes due to infection. The qSOFA includes the following items and scoring system:\n\n1. Altered mental status (1 point),\n2. Systolic blood pressure (SBP)of 100 mm Hg or less (1 point), and\n3. Respiratory rate (RR) of 22 breaths\u002Fmin or more (1 point).",{"measure":68,"description":69,"timeFrame":12},"Pneumonia","Acute infection of the pulmonary parenchyma that is associated with at least one sign or symptom of lower respiratory acute infection (e.g., cough, pleuritic chest pain) or acute systemic illness (e.g., fever, chills, confusion, hypoxemia); accompanied by the presence of an acute infiltrate\u002Fconsolidation on a chest radiograph or auscultatory findings consistent with pneumonia (such as crackles and\u002For localized rales) for which there is no other explanation.",{"measure":71,"description":72,"timeFrame":12},"Bleeding","Life threatening, major or critical organ bleeding",{"measure":74,"description":75,"timeFrame":12},"Hip reoperation","Any second surgical procedure undertaken on the fractured hip being followed in the study, for any reason (e.g. infection, implant failure, periprosthetic fracture, wound dehiscence, etc.), after it has been initially repaired and the patient has left the operating room.",{"measure":77,"description":78,"timeFrame":12},"Prosthetic hip dislocation","Any acute dislocation of a prosthetic femoral head from within its intended concentric location within the acetabulum. The acetabulum may or may not be resurfaced\u002Freplaced.",{"measure":80,"description":81,"timeFrame":12},"Implant failure","Any mechanical issue related to the integrity of any component of the hip implant which requires a surgical procedure to correct. This includes: loss of implant fixation to bone (either with or without associated periprosthetic fracture); or broken, disassociated, or dislocated implant components.",{"measure":83,"description":84,"timeFrame":12},"Peri-prosthetic fracture","Fracture through any part of either the femur and\u002For acetabulum to which a hip implant used for hip repair\u002Freconstruction was fixed.",{"measure":86,"description":87,"timeFrame":12},"Acute kidney injury","An increase in the serum creatinine concentration from the pre-randomization value of ≥26.5 μmol\u002FL (≥0.3 mg\u002FdL) within 48 hours after randomization, or an increase of ≥50% within 7 days after randomization.",{"measure":89,"description":90,"timeFrame":12},"Acute renal failure resulting in dialysis","New requirement for dialysis (i.e., use of hemodialysis machine or peritoneal dialysis apparatus in patients without a requirement for dialysis prior to randomization).",{"measure":92,"description":93,"timeFrame":12},"Hospital re-admission","Hospital re-admission following discharge from index hospitalization",{"measure":95,"description":95,"timeFrame":12},"Length of critical care stay",{"measure":97,"description":97,"timeFrame":12},"Length of rehabilitation stay",{"measure":99,"description":100,"timeFrame":12},"Days alive at home","Days alive at home are the number of days patients spend at their usual residence without, during that day, being admitted to a hospital or visiting an emergency department or urgent-care centre. Patients lose days alive at home if 1. patients go to an emergency department or urgent-care centre; 2. they become inpatients at a hospital or rehabilitation or convalescence-care facility; or 3. they die.",{"allocation":102,"interventionModel":103,"interventionModelDescription":104,"primaryPurpose":105,"observationalModel":104,"timePerspective":104,"maskingInfo":106},"RANDOMIZED","PARALLEL",null,"TREATMENT",{"masking":107,"maskingDescription":104,"whoMasked":108},"SINGLE",[109],"OUTCOMES_ASSESSOR",[111,117],{"label":112,"type":113,"description":114,"interventionNames":115},"Accelerated medical clearance and surgery","EXPERIMENTAL","Accelerated medical clearance and targeted arrival to the operating room within 6 hours of eligibility criteria met.",[116],"Other: Accelerated medical clearance and surgery",{"label":118,"type":119,"description":120,"interventionNames":104},"Standard surgical care","NO_INTERVENTION","Hip fracture repair and surgical care according to treating institution guidelines.",[122],{"type":6,"name":112,"description":123,"armGroupLabels":124,"otherNames":104},"Rapid medical clearance with targeted arrival to the operating room within 6 hours of eligibility criteria criteria met.",[112],[126,129,132,135],{"name":127,"affiliation":5,"role":128},"Flavia Borges, M.D","PRINCIPAL_INVESTIGATOR",{"name":130,"affiliation":131,"role":128},"Gerard Slobogean, M.D","UC Irvine",{"name":133,"affiliation":134,"role":128},"Robert Feibel, M.D","The Ottawa Hospital",{"name":136,"affiliation":5,"role":137},"PJ Devereaux, M.D","STUDY_CHAIR",[139],{"name":140,"role":141,"phone":142,"phoneExt":143,"email":144},"Valerie Harvey","CONTACT","905-297-3479","40793","valerie.harvey@phri.ca",[146,160,170,179,189,199,209,215,225,234,244,254,264,274,284,294,304,314,324,334,343,353,363,372,392,404,422,434,451,462,481,497,513,530,549,562,573,588,604,626,636,645,662,680,699,715,731,747,765,777,787,806,825,844,866,881,898,908,927,947,962,984,1003,1015,1030,1048,1061,1074,1080,1089,1104,1120,1137,1153,1168,1184,1204],{"facility":147,"status":148,"city":149,"state":150,"zip":151,"country":152,"countryCode":153,"cosmosGeoPoint":154,"geoPoint":159,"contacts":104},"Chandler Regional Medical Center","ACTIVE_NOT_RECRUITING","Chandler","Arizona","85224","United States","US",{"type":155,"coordinates":156},"Point",[157,158],-111.84125,33.30616,{"lat":158,"lon":157},{"facility":161,"status":148,"city":162,"state":163,"zip":164,"country":152,"countryCode":153,"cosmosGeoPoint":165,"geoPoint":169,"contacts":104},"The Regents of the University of California","Davis","California","95618",{"type":155,"coordinates":166},[167,168],-121.74052,38.54491,{"lat":168,"lon":167},{"facility":171,"status":148,"city":172,"state":163,"zip":173,"country":152,"countryCode":153,"cosmosGeoPoint":174,"geoPoint":178,"contacts":104},"University of California, Irvine","Irvine","92697",{"type":155,"coordinates":175},[176,177],-117.82311,33.66946,{"lat":177,"lon":176},{"facility":180,"status":148,"city":181,"state":182,"zip":183,"country":152,"countryCode":153,"cosmosGeoPoint":184,"geoPoint":188,"contacts":104},"Yale New Haven Hospital","New Haven","Connecticut","06520",{"type":155,"coordinates":185},[186,187],-72.92816,41.30815,{"lat":187,"lon":186},{"facility":190,"status":148,"city":191,"state":192,"zip":193,"country":152,"countryCode":153,"cosmosGeoPoint":194,"geoPoint":198,"contacts":104},"Emory University at Grady Memorial Hospital","Atlanta","Georgia","30322",{"type":155,"coordinates":195},[196,197],-84.38798,33.749,{"lat":197,"lon":196},{"facility":200,"status":148,"city":201,"state":202,"zip":203,"country":152,"countryCode":153,"cosmosGeoPoint":204,"geoPoint":208,"contacts":104},"University of Maryland","Baltimore","Maryland","20742",{"type":155,"coordinates":205},[206,207],-76.61219,39.29038,{"lat":207,"lon":206},{"facility":210,"status":148,"city":201,"state":202,"zip":211,"country":152,"countryCode":153,"cosmosGeoPoint":212,"geoPoint":214,"contacts":104},"Sinai Hospital of Baltimore","21215",{"type":155,"coordinates":213},[206,207],{"lat":207,"lon":206},{"facility":216,"status":148,"city":217,"state":218,"zip":219,"country":152,"countryCode":153,"cosmosGeoPoint":220,"geoPoint":224,"contacts":104},"Tufts Medical Center","Boston","Massachusetts","02111",{"type":155,"coordinates":221},[222,223],-71.05977,42.35843,{"lat":223,"lon":222},{"facility":226,"status":148,"city":227,"state":218,"zip":228,"country":152,"countryCode":153,"cosmosGeoPoint":229,"geoPoint":233,"contacts":104},"Lahey Hospital and Medical Center","Burlington","01805",{"type":155,"coordinates":230},[231,232],-71.19561,42.50482,{"lat":232,"lon":231},{"facility":235,"status":148,"city":236,"state":237,"zip":238,"country":152,"countryCode":153,"cosmosGeoPoint":239,"geoPoint":243,"contacts":104},"University of Michigan","Ann Arbor","Michigan","48109",{"type":155,"coordinates":240},[241,242],-83.74088,42.27756,{"lat":242,"lon":241},{"facility":245,"status":148,"city":246,"state":247,"zip":248,"country":152,"countryCode":153,"cosmosGeoPoint":249,"geoPoint":253,"contacts":104},"Mayo Clinic","Rochester","Minnesota","55905",{"type":155,"coordinates":250},[251,252],-92.4699,44.02163,{"lat":252,"lon":251},{"facility":255,"status":148,"city":256,"state":257,"zip":258,"country":152,"countryCode":153,"cosmosGeoPoint":259,"geoPoint":263,"contacts":104},"Bryan Medical Center","Lincoln","Nebraska","68506",{"type":155,"coordinates":260},[261,262],-96.66696,40.8,{"lat":262,"lon":261},{"facility":265,"status":148,"city":266,"state":267,"zip":268,"country":152,"countryCode":153,"cosmosGeoPoint":269,"geoPoint":273,"contacts":104},"University Medical Center of Southern Nevada","Las Vegas","Nevada","89102",{"type":155,"coordinates":270},[271,272],-115.13722,36.17497,{"lat":272,"lon":271},{"facility":275,"status":148,"city":276,"state":277,"zip":278,"country":152,"countryCode":153,"cosmosGeoPoint":279,"geoPoint":283,"contacts":104},"Dartmouth-Hitchcock Medical Center","Lebanon","New Hampshire","03756",{"type":155,"coordinates":280},[281,282],-72.25176,43.64229,{"lat":282,"lon":281},{"facility":285,"status":148,"city":286,"state":287,"zip":288,"country":152,"countryCode":153,"cosmosGeoPoint":289,"geoPoint":293,"contacts":104},"Montefiore Medical Center","The Bronx","New York","10467",{"type":155,"coordinates":290},[291,292],-73.86641,40.84985,{"lat":292,"lon":291},{"facility":295,"status":148,"city":296,"state":297,"zip":298,"country":152,"countryCode":153,"cosmosGeoPoint":299,"geoPoint":303,"contacts":104},"Cleveland Clinic","Cleveland","Ohio","44195",{"type":155,"coordinates":300},[301,302],-81.69541,41.4995,{"lat":302,"lon":301},{"facility":305,"status":148,"city":306,"state":307,"zip":308,"country":152,"countryCode":153,"cosmosGeoPoint":309,"geoPoint":313,"contacts":104},"Oregon Health and Science University","Portland","Oregon","97239",{"type":155,"coordinates":310},[311,312],-122.67621,45.52345,{"lat":312,"lon":311},{"facility":315,"status":148,"city":316,"state":317,"zip":318,"country":152,"countryCode":153,"cosmosGeoPoint":319,"geoPoint":323,"contacts":104},"St. Luke's University Health Network","Bethlehem","Pennsylvania","18015",{"type":155,"coordinates":320},[321,322],-75.37046,40.62593,{"lat":322,"lon":321},{"facility":325,"status":148,"city":326,"state":327,"zip":328,"country":152,"countryCode":153,"cosmosGeoPoint":329,"geoPoint":333,"contacts":104},"The University of Texas Southwestern Medical Center (UTSW)","Dallas","Texas","75390",{"type":155,"coordinates":330},[331,332],-96.80667,32.78306,{"lat":332,"lon":331},{"facility":335,"status":148,"city":336,"state":327,"zip":337,"country":152,"countryCode":153,"cosmosGeoPoint":338,"geoPoint":342,"contacts":104},"The University of Texas Health Science Center at Houston","Houston","77030",{"type":155,"coordinates":339},[340,341],-95.36327,29.76328,{"lat":341,"lon":340},{"facility":344,"status":148,"city":345,"state":346,"zip":347,"country":152,"countryCode":153,"cosmosGeoPoint":348,"geoPoint":352,"contacts":104},"University of Utah","Salt Lake City","Utah","84112",{"type":155,"coordinates":349},[350,351],-111.89105,40.76078,{"lat":351,"lon":350},{"facility":354,"status":148,"city":355,"state":356,"zip":357,"country":152,"countryCode":153,"cosmosGeoPoint":358,"geoPoint":362,"contacts":104},"University of Wisconsin","Madison","Wisconsin","53715",{"type":155,"coordinates":359},[360,361],-89.40123,43.07305,{"lat":361,"lon":360},{"facility":364,"status":148,"city":365,"state":356,"zip":366,"country":152,"countryCode":153,"cosmosGeoPoint":367,"geoPoint":371,"contacts":104},"Froedtert Hospital","Milwaukee","53226",{"type":155,"coordinates":368},[369,370],-87.90647,43.0389,{"lat":370,"lon":369},{"facility":373,"status":374,"city":375,"state":376,"zip":377,"country":378,"countryCode":379,"cosmosGeoPoint":380,"geoPoint":384,"contacts":385},"The John Hunter Hospital","RECRUITING","New Lambton Heights","New South Wales","2305","Australia","AU",{"type":155,"coordinates":381},[382,383],151.69364,-32.92466,{"lat":383,"lon":382},[386,390],{"name":387,"role":141,"phone":388,"phoneExt":104,"email":389},"Debra McDougall","61 + 2-4921-3000","Debra.McDougall@health.nsw.gov.au",{"name":391,"role":128,"phone":104,"phoneExt":104,"email":104},"Zsolt Balogh, MD",{"facility":393,"status":148,"city":394,"state":395,"zip":396,"country":397,"countryCode":398,"cosmosGeoPoint":399,"geoPoint":403,"contacts":104},"Cliniques Universitaires Saint Luc - University Catholic of Louvain","Woluwe-Saint-Lambert","Brussels Capital","1200","Belgium","BE",{"type":155,"coordinates":400},[401,402],4.42912,50.84389,{"lat":402,"lon":401},{"facility":405,"status":374,"city":406,"state":406,"zip":407,"country":408,"countryCode":409,"cosmosGeoPoint":410,"geoPoint":414,"contacts":415},"University of São Paulo","São Paulo","05403010","Brazil","BR",{"type":155,"coordinates":411},[412,413],-46.63611,-23.5475,{"lat":413,"lon":412},[416,420],{"name":417,"role":141,"phone":418,"phoneExt":104,"email":419},"Maria (Adelaide) Gongalves, MD","55 + 11-3091-3116","Adelaidemiranda99@gmail.com",{"name":421,"role":128,"phone":104,"phoneExt":104,"email":104},"Kodi Kojima, MD",{"facility":423,"status":148,"city":424,"state":425,"zip":426,"country":427,"countryCode":428,"cosmosGeoPoint":429,"geoPoint":433,"contacts":104},"University of Alberta Hospital","Edmonton","Alberta","T6G 2B7","Canada","CA",{"type":155,"coordinates":430},[431,432],-113.46871,53.55014,{"lat":432,"lon":431},{"facility":435,"status":374,"city":436,"state":437,"zip":438,"country":427,"countryCode":428,"cosmosGeoPoint":439,"geoPoint":443,"contacts":444},"St. Joseph's Healthcare Hamilton","Hamilton","Ontario","L8N 4A6",{"type":155,"coordinates":440},[441,442],-79.84963,43.25011,{"lat":442,"lon":441},[445,449],{"name":446,"role":141,"phone":447,"phoneExt":104,"email":448},"Krysten Gregus","905-521-2100","gregus@hhsc.ca",{"name":450,"role":128,"phone":104,"phoneExt":104,"email":104},"Flavia Borges, MD",{"facility":452,"status":374,"city":436,"state":437,"zip":453,"country":427,"countryCode":428,"cosmosGeoPoint":454,"geoPoint":456,"contacts":457},"Juravinski Hospital","L8V 1C3",{"type":155,"coordinates":455},[441,442],{"lat":442,"lon":441},[458,460],{"name":446,"role":141,"phone":447,"phoneExt":104,"email":459},"gregus@HHSC.ca",{"name":461,"role":128,"phone":104,"phoneExt":104,"email":104},"Ameen Patel, MD",{"facility":463,"status":374,"city":464,"state":437,"zip":465,"country":427,"countryCode":428,"cosmosGeoPoint":466,"geoPoint":470,"contacts":471},"Victoria Hospital","London","N6A 5W9",{"type":155,"coordinates":467},[468,469],-81.23304,42.98339,{"lat":469,"lon":468},[472,476,479],{"name":473,"role":141,"phone":474,"phoneExt":104,"email":475},"Fatma Alqahwaji","519-685-8500","Fatma.alqahwaji@lhsc.on.ca",{"name":477,"role":141,"phone":104,"phoneExt":104,"email":478},"Reem Ansari","Reem.Ansari@lhsc.on.ca",{"name":480,"role":128,"phone":104,"phoneExt":104,"email":104},"Abdel Lawendy, MD",{"facility":482,"status":374,"city":483,"state":437,"zip":484,"country":427,"countryCode":428,"cosmosGeoPoint":485,"geoPoint":489,"contacts":490},"Markham Stouffville Hospital","Markham","L3P 7P3",{"type":155,"coordinates":486},[487,488],-79.2663,43.86682,{"lat":488,"lon":487},[491,495],{"name":492,"role":141,"phone":493,"phoneExt":104,"email":494},"Michelle Dimas","905-472-7373","mdimas@oakvalleyhealth.ca",{"name":496,"role":128,"phone":104,"phoneExt":104,"email":104},"Steve McMahon, MD",{"facility":498,"status":374,"city":499,"state":437,"zip":500,"country":427,"countryCode":428,"cosmosGeoPoint":501,"geoPoint":505,"contacts":506},"Ottawa General Hospital","Ottawa","K1H 8L6",{"type":155,"coordinates":502},[503,504],-75.69812,45.41117,{"lat":504,"lon":503},[507,511],{"name":508,"role":141,"phone":509,"phoneExt":104,"email":510},"Katie Mcliquham","613-722-7000","kmcilquham@ohri.ca",{"name":512,"role":128,"phone":104,"phoneExt":104,"email":104},"Robert Feibel, MD",{"facility":514,"status":374,"city":515,"state":516,"zip":517,"country":427,"countryCode":428,"cosmosGeoPoint":518,"geoPoint":522,"contacts":523},"CISSS de Laval","Laval","Quebec","H7M 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MD",{"facility":1169,"status":374,"city":1170,"state":104,"zip":1171,"country":1034,"countryCode":1035,"cosmosGeoPoint":1172,"geoPoint":1176,"contacts":1177},"Hospital Universitario Ramón y Cajal","Madrid","28034",{"type":155,"coordinates":1173},[1174,1175],-3.70256,40.4165,{"lat":1175,"lon":1174},[1178,1182],{"name":1179,"role":141,"phone":1180,"phoneExt":104,"email":1181},"Yolanda Diez Remesal","34 + 913 36 80 00","yolan10@gmail.com",{"name":1183,"role":128,"phone":104,"phoneExt":104,"email":104},"Yolanda Diez Remesal, MD",{"facility":1185,"status":374,"city":464,"state":104,"zip":1186,"country":1187,"countryCode":1188,"cosmosGeoPoint":1189,"geoPoint":1193,"contacts":1194},"Chelsea and Westminster Hospital","SW10 9NH","United Kingdom","UK",{"type":155,"coordinates":1190},[1191,1192],-0.12574,51.50853,{"lat":1192,"lon":1191},[1195,1199,1202],{"name":1196,"role":141,"phone":1197,"phoneExt":104,"email":1198},"Julie Logan","44 + 20-3315-8000","julie.logan11@nhs.net",{"name":1200,"role":141,"phone":1197,"phoneExt":104,"email":1201},"Laura Martins","l.martins2@nhs.net",{"name":1203,"role":128,"phone":104,"phoneExt":104,"email":104},"Marcela Vizcaychipi, MD",{"facility":1205,"status":374,"city":1206,"state":104,"zip":1207,"country":1187,"countryCode":1188,"cosmosGeoPoint":1208,"geoPoint":1212,"contacts":1213},"West Middlesex University Hospital","Middlesex","TW7 6AF",{"type":155,"coordinates":1209},[1210,1211],-0.26856,51.53174,{"lat":1211,"lon":1210},[1214,1218,1222],{"name":1215,"role":141,"phone":1216,"phoneExt":104,"email":1217},"Amrinder Sayan","44+ 208-321-5181","amrinder.sayan@nhs.net",{"name":1219,"role":141,"phone":1220,"phoneExt":104,"email":1221},"Jamie Gonzales","44 + 208-321-5181","jamie.gonzales@nhs.net",{"name":1223,"role":128,"phone":104,"phoneExt":104,"email":104},"Surendini Thayaparan, MD",{"type":1225,"investigatorFullName":104,"investigatorTitle":104,"investigatorAffiliation":104,"oldNameTitle":104,"oldOrganization":104},"SPONSOR",[1227,1230],{"name":1228,"class":1229},"Canadian Institutes of Health Research (CIHR)","OTHER_GOV",{"name":1231,"class":1232},"National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)","NIH","100419595","hip-fracture-accelerated-surgical-treatment-and-care-track-2-trial-100419595",false,"NCT04743765","HIP Fracture Accelerated Surgical TreaTment And Care tracK 2 Trial","HIP Fracture Accelerated Surgical TreaTment And Care tracK 2 (HIP ATTACK-2) Trial","HIP ATTACK-2","Inclusion Criteria:\n\n1. age ≥45 years;\n2. diagnosis of hip fracture during working hours with a low-energy mechanism requiring surgery;\n3. troponin elevation ( at least one troponin measurement above the upper limit of normal occurring from the time of hip fracture to the time of randomization); and\n4. informed consent.\n\nExclusion Criteria:\n\n1. taking a therapeutic dose of an anticoagulant for which no reversing agent is available and the anesthesiologist or surgeon believe surgery within 6 hours of eligibility criteria met would not be safe;\n2. patients on a therapeutic vitamin K antagonist with a history of heparin induced thrombocytopenia (HIT);\n3. patients with peri-prosthetic fracture, open fracture or bilateral fractures;\n4. patients requiring an emergency surgery for another reason (e.g., subdural hematoma);\n5. patients with acute myocardial infarction deemed to be clinically unstable, with a mechanical complication (i.e., acute papillary muscle rupture, ventricular septal defect), ST elevation myocardial infarction, or cardiogenic shock;\n6. patients refusing consent; or\n7. patients previously enrolled in HIP ATTACK-2.","ALL","45 Years",{"count":1244,"type":1245},1100,"ESTIMATED","INTERVENTIONAL",[1248],"NA","The HIP ATTACK-2 trial is a multicentre, international, parallel group randomized controlled trial to determine whether accelerated surgery for hip fracture in patients with acute myocardial injury is superior to standard care in reducing death at 90 days after randomization. The trial will also assess secondary outcomes at 90 days after randomization: inability to independently walk 3 metres, time to first mobilization (first standing and first full weight bear), composite and individual assessment of major complications (e.g., mortality, non-fatal myocardial infarction, acute congestive heart failure, and stroke), delirium, length of stay, pain, and quality of life.",[1251,1252],"Hip Fractures","Myocardial Injury","2026-08-24",{"date":1255,"type":1256},"2026-08-26","ACTUAL",{"date":1258,"type":1256},"2021-11-22",{"date":1260,"type":1245},"2027-11-30",{"name":5,"class":6},77]