[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100563713":3},{"organization":4,"outcomesModule":7,"designInfo":15,"detailedDescription":14,"studyPopulation":18,"armGroups":14,"interventions":14,"overallOfficials":14,"centralContacts":19,"locations":14,"responsibleParty":28,"collaborators":14,"id":32,"slug":33,"hasResults":34,"nctId":35,"briefTitle":36,"officialTitle":37,"acronym":14,"eligibilityCriteria":38,"healthyVolunteers":34,"sex":39,"minAge":40,"maxAge":41,"enrollmentInfo":42,"targetDuration":14,"studyType":45,"phases":14,"briefSummary":46,"conditions":47,"keywords":14,"overallStatus":52,"whyStopped":14,"lastUpdateSubmitDate":53,"lastUpdatePostDateStruct":54,"startDateStruct":57,"completionDateStruct":58,"leadSponsor":60,"locationsCount":14},{"fullName":5,"class":6},"Peking Union Medical College Hospital","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":14,"otherOutcomes":14},[9,12],{"measure":10,"description":10,"timeFrame":11},"Detection rate of cervical intraepithelial neoplasia grade 2 or above (CIN2+) in women infected with HIV within 5 years","5 years",{"measure":13,"description":13,"timeFrame":11},"Detection rate of cervical intraepithelial neoplasia grade 3 and above (CIN3+) in women infected with HIV within 5 years",null,{"allocation":14,"interventionModel":14,"interventionModelDescription":14,"primaryPurpose":14,"observationalModel":16,"timePerspective":17,"maskingInfo":14},"COHORT","PROSPECTIVE","HIV-infected women",[20,25],{"name":21,"role":22,"phone":23,"phoneExt":14,"email":24},"Roujie Huang","CONTACT","+8618373153750","hroujie@163.com",{"name":26,"role":22,"phone":14,"phoneExt":14,"email":27},"Lan Zhu, MD","zhu_julie@vip.sina.com",{"type":29,"investigatorFullName":30,"investigatorTitle":31,"investigatorAffiliation":5,"oldNameTitle":14,"oldOrganization":14},"SPONSOR_INVESTIGATOR","Lan Zhu","Director of the Department of Obstetrics and Gynecology at Peking Union Medical College Hospital","100563713","hpv-infection-and-vaginal-microecology-in-immunosuppressed-women-100563713",false,"NCT06619743","HPV Infection and Vaginal Microecology in Immunosuppressed Women","Study on HPV Infection and Vaginal Microecology in Immunosuppressed Women","Inclusion Criteria:\n\n* HIV positive female, ≥18 years old\n* HIV infection is sexually transmitted\n* Have an intact cervix\n* Have not received cervical cancer screening in the past 1 year\n* No previous treatment for CIN\u002Fcervical cancer\n* No clinical pregnancy symptoms\n\nExclusion Criteria:\n\n* Women who have had a previous cervical resection\n* Unable to complete all screening processes independently\n* Unable or unwilling to accept follow-up\n* For subjects in vaginal microecology studies, women who used antibiotics within 2 weeks before collecting vaginal secretions, had sexual intercourse within 3 days, or used vaginal medication or vaginal douching within 48 hours need to be further excluded.","FEMALE","18 Years","75 Years",{"count":43,"type":44},10000,"ESTIMATED","OBSERVATIONAL","This study intends to establish a screening cohort for HPV infection and related tumors in areas with high incidence of HIV infection, explore the screening of cervical cancer and anal cancer and the prognosis management model of precancerous lesions in HIV-infected women, and provide a scientific basis for the formulation of malignant tumor screening policies for this population in my country. In addition, this study intends to characterize the cervical, vaginal, and intestinal microecological characteristics of women with different HIV\u002FHPV infection status, so as to explore the impact of cervical, vaginal, and intestinal microecological characteristics on persistent HPV infection or CIN\u002Fcancer progression.",[48,49,50,51],"HIV Infections","HPV Infection","Cervical Cancer","Anal Cancer","NOT_YET_RECRUITING","2024-09-27",{"date":55,"type":56},"2024-10-01","ACTUAL",{"date":55,"type":44},{"date":59,"type":44},"2029-12-31",{"name":30,"class":6}]