[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100652184":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":21,"centralContacts":28,"locations":33,"responsibleParty":47,"collaborators":20,"id":50,"slug":51,"hasResults":52,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":20,"eligibilityCriteria":56,"healthyVolunteers":52,"sex":57,"minAge":58,"maxAge":59,"enrollmentInfo":60,"targetDuration":20,"studyType":63,"phases":64,"briefSummary":66,"conditions":67,"keywords":69,"overallStatus":75,"whyStopped":20,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":85},{"fullName":5,"class":6},"Cairo University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"CAF + CTG + Hyaluronic Acid and Polynucleotides","EXPERIMENTAL","Participants with RT II gingival recession will receive coronally advanced flap surgery with a de-epithelialized connective tissue graft combined with hyaluronic acid and polynucleotides.",[13],"Procedure: Coronally Advanced Flap with Connective Tissue Graft and Hyaluronic Acid\u002FPolynucleotides",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"PROCEDURE","Coronally Advanced Flap with Connective Tissue Graft and Hyaluronic Acid\u002FPolynucleotides","A coronally advanced flap will be performed with a de-epithelialized connective tissue graft. Approximately 1-2 mL of a hyaluronic acid and polynucleotide mixture will be applied to the graft before suturing",[9],null,[22,25],{"name":23,"affiliation":5,"role":24},"HASSAN NIDAL FANDI, BDS","PRINCIPAL_INVESTIGATOR",{"name":26,"affiliation":5,"role":27},"Dr.Manal Hosny","STUDY_CHAIR",[29],{"name":23,"role":30,"phone":31,"phoneExt":20,"email":32},"CONTACT","+201011066726","hassan.fandi@dentistry.cu.edu.eg",[34],{"facility":35,"status":20,"city":36,"state":20,"zip":20,"country":37,"countryCode":38,"cosmosGeoPoint":39,"geoPoint":44,"contacts":45},"Faculty of Dentistry, Cairo University","Cairo","Egypt","EG",{"type":40,"coordinates":41},"Point",[42,43],31.24967,30.06263,{"lat":43,"lon":42},[46],{"name":23,"role":30,"phone":31,"phoneExt":20,"email":32},{"type":24,"investigatorFullName":48,"investigatorTitle":49,"investigatorAffiliation":5,"oldNameTitle":20,"oldOrganization":20},"hassan nidal fandi","Master Student - Periodontology","100652184","hyaluronic-acid-and-polynucleotides-with-connective-tissue-graft-and-coronally-advanced-flap-for-rt-ii-gingival-recession-100652184",false,"NCT07771244","Hyaluronic Acid and Polynucleotides With Connective Tissue Graft and Coronally Advanced Flap for RT II Gingival Recession","Assessment of Injectable Hyaluronic Acid Combined With Polynucleotides With Coronally Advanced Flap and Connective Tissue Graft in Treatment of RT II Gingival Recession Defects for Covering Gingival Recession","Inclusion Criteria:\n\n* Patients with RT II gingival recession.\n* Age range: 15-60 years.\n* Systemically healthy patients with no contraindications to surgery.\n* Patients who have not had previous periodontal surgery in the area of treatment.\n\nExclusion Criteria:\n\n* Periodontitis.\n* Active systemic disease affecting wound healing.\n* Pregnancy or breastfeeding.\n* Improperly aligned teeth or teeth with cervical restorations or crowns.\n* Non-carious cervical lesions","ALL","15 Years","60 Years",{"count":61,"type":62},12,"ESTIMATED","INTERVENTIONAL",[65],"NA","This case series will evaluate the effectiveness of injectable hyaluronic acid combined with polynucleotides as an adjunct to coronally advanced flap and connective tissue graft in patients with RT II gingival recession. Twelve patients will be included and followed for 6 months. Clinical outcomes will include percentage of root coverage, clinical attachment level gain, gingival thickness, probing depth, width of keratinized tissue, post-operative pain, and patient aesthetic satisfaction.",[68],"RT II Gingival Recession",[70,68,71,72,73,74],"Gingival Recession","Hyaluronic Acid","Polynucleotides","Coronally Advanced Flap","Connective Tissue Graft","NOT_YET_RECRUITING","2026-08-20",{"date":78,"type":79},"2026-08-21","ACTUAL",{"date":81,"type":62},"2026-09-01",{"date":83,"type":62},"2027-03-01",{"name":5,"class":6},1]