[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100652823":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":29,"centralContacts":33,"locations":38,"responsibleParty":55,"collaborators":57,"id":61,"slug":62,"hasResults":63,"nctId":64,"briefTitle":65,"officialTitle":66,"acronym":9,"eligibilityCriteria":67,"healthyVolunteers":63,"sex":68,"minAge":69,"maxAge":70,"enrollmentInfo":71,"targetDuration":25,"studyType":74,"phases":75,"briefSummary":77,"conditions":78,"keywords":84,"overallStatus":88,"whyStopped":25,"lastUpdateSubmitDate":89,"lastUpdatePostDateStruct":90,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":97,"locationsCount":98},{"fullName":5,"class":6},"University of North Carolina, Chapel Hill","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"ICU-SUCCEED","EXPERIMENTAL","This arm will receive ICU-SUCCEED intervention.",[13],"Behavioral: ICU-SUCCEED",{"label":15,"type":16,"description":17,"interventionNames":18},"Augmented Usual Care","PLACEBO_COMPARATOR","This arm will receive standard care routinely available plus written handouts prior to hospital discharge.",[19],"Other: Augmented Usual Care",[21,26],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"BEHAVIORAL","Includes one inpatient (in-person) session followed by four outpatient (Zoom or telephone) sessions. Dyads will receive one session every 1-2 weeks. Each session will have a different focus, which may incorporate one of the following: communication, self-management, emotion management, stress management, lifestyle and hobbies, and interpersonal relationship building. This intervention has been adapted to meet the needs of patients with acute respiratory failure and their caregivers",[9],null,{"type":6,"name":15,"description":27,"armGroupLabels":28,"otherNames":25},"Usual care will continue unchanged and will include any services, counseling, monitoring, or referrals that are coordinated by the clinical team prior to discharge. Handouts include a hospital discharge preparation checklist and information about the long-term complications of and recovery from critical illness.",[15],[30],{"name":31,"affiliation":5,"role":32},"Blair Wendlandt, MD, MSCR","PRINCIPAL_INVESTIGATOR",[34],{"name":31,"role":35,"phone":36,"phoneExt":25,"email":37},"CONTACT","(984)542-7702","succeed_icu@med.unc.edu",[39],{"facility":40,"status":25,"city":41,"state":42,"zip":43,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"UNC Hospitals","Chapel Hill","North Carolina","27599","United States","US",{"type":47,"coordinates":48},"Point",[49,50],-79.05584,35.9132,{"lat":50,"lon":49},[53],{"name":31,"role":35,"phone":54,"phoneExt":25,"email":37},"984-542-7702",{"type":56,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR",[58],{"name":59,"class":60},"National Heart, Lung, and Blood Institute (NHLBI)","NIH","100652823","icu-succeed-for-survivors-of-acute-respiratory-failure-and-their-caregivers-100652823",false,"NCT07778004","ICU-SUCCEED for Survivors of Acute Respiratory Failure and Their Caregivers","A Pilot Randomized Trial of the Self-Management Using Couples' Coping EnhancEment in Diseases Intervention for Survivors of Acute Respiratory Failure and Their Family Caregivers","Patient Inclusion Criteria\n\n* Admitted to the medical ICU at UNC with acute respiratory failure (functional lung impairment resulting in hypoxia, hypercapnia, or both) and\u002For sepsis with significant end organ dysfunction.\n* At least 18 years old\n* Survives to hospital discharge\n* Is expected to be discharged home or to an acute inpatient rehabilitation center with a clear plan to be subsequently discharged home\n* Capable of providing written informed consent\n* Has English language proficiency\n\nCaregiver Inclusion Criteria\n\n* Provides emotional, physical, and\u002For financial support to the patient in a non-professional, unpaid capacity\n* Must be related to the patient in one of the following ways: a spouse or domestic partner, an adult child, a parent, or a sibling\n* At least 18 years of age\n* Has English language proficiency\n* Must be the caregiver of a patient that meets the patient eligibility criteria listed above\n\nPatient Exclusion Criteria:\n\n* No available family caregiver\n* Lacks decision-making capacity\n* Under 18 years of age\n* Living at a location other than home prior to admission\n* Unhoused prior to admission\n* Receives extracorporeal membrane oxygenation (ECMO) during hospital stay\n* Expected to discharge to any location other than home or an acute inpatient rehabilitation center\n* Does not have English language proficiency\n\nCaregiver Exclusion Criteria\n\n* Does not provide emotional, physical, and\u002For financial support to the patient in a non-profession, unpaid capacity\n* Is not related to the patient in one of the following ways: a spouse or domestic partner, an adult child, a parent, or a sibling\n* Cannot complete surveys or engage in other study activities due to physical or cognitive limitations\n* Unhoused prior to admission\n* Is under 18 years of age\n* Does not have English language proficiency\n* Is not the caregiver of a patient that meets the patient eligibility criteria listed above","ALL","18 Years","99 Years",{"count":72,"type":73},144,"ESTIMATED","INTERVENTIONAL",[76],"NA","This study will investigate whether a family-centered intervention that has been adapted for patients with critical illness and their caregivers is possible, acceptable, and helpful",[79,80,81,82,83],"Acute Respiratory Failure","Critical Illness","Sepsis","Hypoxia","Hypercapnia",[79,85,86,81,87],"Family-Centered Intervention","Critical illness","Septic shock","NOT_YET_RECRUITING","2026-08-18",{"date":91,"type":92},"2026-08-21","ACTUAL",{"date":94,"type":73},"2026-09-01",{"date":96,"type":73},"2030-09-01",{"name":5,"class":6},1]