[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100654627":3},{"organization":4,"outcomesModule":7,"designInfo":44,"detailedDescription":51,"studyPopulation":47,"armGroups":52,"interventions":59,"overallOfficials":47,"centralContacts":65,"locations":72,"responsibleParty":89,"collaborators":93,"id":97,"slug":98,"hasResults":99,"nctId":100,"briefTitle":101,"officialTitle":102,"acronym":103,"eligibilityCriteria":104,"healthyVolunteers":105,"sex":106,"minAge":107,"maxAge":47,"enrollmentInfo":108,"targetDuration":47,"studyType":111,"phases":112,"briefSummary":113,"conditions":114,"keywords":116,"overallStatus":74,"whyStopped":47,"lastUpdateSubmitDate":124,"lastUpdatePostDateStruct":125,"startDateStruct":128,"completionDateStruct":130,"leadSponsor":132,"locationsCount":133},{"fullName":5,"class":6},"Consorci Sanitari de Terrassa","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":32},[9],{"measure":10,"description":11,"timeFrame":12},"Change in cognitive function (verbal fluency and Digit Span tests)","Cognitive function is assessed using verbal fluency tasks and Digit Span tests (forward and backward). Verbal fluency evaluates language and executive function by measuring the number of words generated under specific conditions. Digit Span forward assesses attention, while Digit Span backward assesses working memory. Higher scores indicate better cognitive performance.","Baseline (pre-intervention) and immediately post-intervention (1 week)",[14,17,20,23,26,29],{"measure":15,"description":16,"timeFrame":12},"Change in anxiety symptoms (Generalized Anxiety Disorder 7-item scale [GAD-7])","Anxiety symptoms are assessed using the GAD-7 questionnaire, a validated self-report scale measuring severity of generalized anxiety symptoms. Higher scores indicate greater anxiety.",{"measure":18,"description":19,"timeFrame":12},"Short-form Yesavage Geriatric Depression Scale (GDS-SF)","Depressive symptoms are assessed using the GDS-SF, a validated screening tool for depression in older adults. Higher scores indicate greater depressive symptomatology.",{"measure":21,"description":22,"timeFrame":12},"Change in positive and negative affect (Positive and Negative Affect Schedule-10 [PANAS-10])","Affective state is assessed using the PANAS-10, which measures positive and negative affect. Higher scores reflect higher levels of the corresponding affect.",{"measure":24,"description":25,"timeFrame":12},"Change in loneliness (UCLA Loneliness Scale, UCLA-10)","Loneliness is assessed using the UCLA-10 scale, a validated self-report measure of perceived social isolation. Higher scores indicate greater loneliness.",{"measure":27,"description":28,"timeFrame":12},"Change in quality of life (EuroQol 5-Dimension 5-Level questionnaire [EQ-5D-5L])","Quality of life is assessed using the EuroQol-5D-5L questionnaire, which evaluates health status across five dimensions. Higher index values indicate better perceived health-related quality of life.",{"measure":30,"description":31,"timeFrame":12},"Change in functional ability (Bayer Activities of Daily Living Scale [BAYER-ADL])","Functional ability is assessed using the Bayer Activities of Daily Living Scale, which measures impairments in instrumental activities of daily living. Higher scores indicate greater functional impairment.",[33,37,40],{"measure":34,"description":35,"timeFrame":36},"Perceived immersion during virtual reality sessions (Self-Assessment Manikin, SAM)","Immersion is assessed using the Self-Assessment Manikin (SAM), a non-verbal pictorial tool that captures participants' subjective experience during exposure to immersive virtual environments.","At the end of virtual reality sessions 4, 7, and 10, during the 1-week intervention period.",{"measure":38,"description":39,"timeFrame":36},"Participant satisfaction with immersive virtual reality sessions","Satisfaction is assessed using an ad hoc questionnaire evaluating participants' experience, acceptability, and perceived usefulness of the intervention.",{"measure":41,"description":42,"timeFrame":43},"Intervention adherence based on session attendance and completion rates","Adherence is measured by attendance rate and completion of the scheduled sessions.","At the end of each intervention day: Day 1 (after session 4), Day 2 (after session 7), and Day 3 (after session 10).",{"allocation":45,"interventionModel":46,"interventionModelDescription":47,"primaryPurpose":48,"observationalModel":47,"timePerspective":47,"maskingInfo":49},"NA","SINGLE_GROUP",null,"PREVENTION",{"masking":50,"maskingDescription":47,"whoMasked":47},"NONE","This study evaluates the effectiveness of an immersive virtual reality program based on nature environments to improve cognitive function, emotional well-being, functional ability, and quality of life in older adults with mild to moderate cognitive impairment.\n\nCognitive impairment is common in older adults and can negatively affect independence, emotional well-being, and quality of life. Non-pharmacological interventions using emerging technologies, such as immersive virtual reality, offer new opportunities to support cognitive and emotional health. Nature-based virtual environments may help reduce stress, improve mood, and increase engagement, even in individuals with limited mobility or access to natural settings.\n\nThe study takes place across services affiliated with Suara Cooperativa. In Phase 1, researchers test and validate immersive virtual environments in healthy participants. Participants attend individual sessions where they view nature-based virtual scenarios. Researchers collect behavioral, subjective, and physiological data, including electroencephalography, heart rate, electrodermal activity, and respiration, to assess safety, usability, and emotional responses to the virtual environments.\n\nIn Phase 2, researchers conduct a quasi-experimental pre-post study without a control group. The study includes 200 participants (100 with mild cognitive impairment and 100 with moderate cognitive impairment) recruited from day care centers and residential facilities managed by Suara Cooperativa.\n\nParticipants take part in a structured group-based intervention consisting of 10 immersive virtual reality sessions. The program combines exposure to nature-based virtual environments with mindfulness practices, cognitive stimulation activities, and breathing techniques to promote emotional regulation and cognitive engagement. The intervention is accessible, engaging, and adapted to the needs of older adults with cognitive impairment.\n\nPrimary outcome measures include cognitive function, emotional well-being, functional capacity in activities of daily living, and quality of life. Researchers also assess participant engagement and acceptability of the intervention as secondary measures.\n\nResearchers analyze data using descriptive and inferential statistical methods to assess changes between pre- and post-intervention measures. They also evaluate adherence to the intervention and participant satisfaction.\n\nThis study aims to generate evidence on the potential of immersive virtual reality as an innovative, safe, and accessible non-pharmacological intervention to support cognitive health, emotional well-being, and autonomy in older adults, contributing to active and healthy aging.",[53],{"label":54,"type":55,"description":56,"interventionNames":57},"Immersive virtual reality intervention","EXPERIMENTAL","Participants receive a group-based immersive virtual reality intervention consisting of 10 sessions using nature-based environments combined with mindfulness, cognitive stimulation, and breathing techniques.",[58],"Device: Immersive virtual reality program",[60],{"type":61,"name":62,"description":63,"armGroupLabels":64,"otherNames":47},"DEVICE","Immersive virtual reality program","Participants receive an immersive virtual reality intervention using nature-based environments. The program consists of 10 group sessions that combine mindfulness, cognitive stimulation, and breathing techniques to promote cognitive and emotional well-being.",[54],[66],{"name":67,"role":68,"phone":69,"phoneExt":70,"email":71},"Maite Garolera, PhD","CONTACT","+34937310007","1558","mgarolera@cst.cat",[73],{"facility":5,"status":74,"city":75,"state":76,"zip":77,"country":78,"countryCode":79,"cosmosGeoPoint":80,"geoPoint":85,"contacts":86},"RECRUITING","Terrassa","Barcelona","08227","Spain","ES",{"type":81,"coordinates":82},"Point",[83,84],2.01667,41.56667,{"lat":84,"lon":83},[87],{"name":67,"role":68,"phone":69,"phoneExt":88,"email":71},"1758",{"type":90,"investigatorFullName":91,"investigatorTitle":92,"investigatorAffiliation":5,"oldNameTitle":47,"oldOrganization":47},"PRINCIPAL_INVESTIGATOR","Maite Garolera","Chief of the Neuropsychological Unit and Director of the Brain, Cognition, and Behavior Research Group",[94],{"name":95,"class":96},"Suara Serveis SCCL","UNKNOWN","100654627","immersive-nature-based-wellbeing-program-in-older-adults-with-cognitive-impairment-100654627",false,"NCT07802392","Immersive Nature-Based Wellbeing Program in Older Adults With Cognitive Impairment","Cognitio Avançada: Immersive Nature-Based Wellbeing Program for Older Adults With Cognitive Impairment: A Quasi-Experimental Pre-Post Study","COGNITIO","Inclusion Criteria:\n\n* Age ≥ 65 years\n* Diagnosis of mild or moderate cognitive impairment\n* Ability to understand study procedures and follow instructions\n* Ability to provide informed consent (or consent provided by a legal representative)\n* Attendance at participating day care centers or residential facilities (Phase 2)\n* For Phase 1: healthy adults without cognitive impairment\n\nExclusion Criteria:\n\n* Severe cognitive impairment or diagnosis of advanced dementia\n* Severe visual, auditory, or motor impairments that prevent use of virtual reality\n* Neurological or psychiatric conditions that may interfere with participation\n* History of epilepsy or conditions contraindicating virtual reality exposure\n* Severe behavioral disturbances or agitation\n* Participation in other clinical studies that may interfere with results",true,"ALL","65 Years",{"count":109,"type":110},230,"ESTIMATED","INTERVENTIONAL",[45],"This study aims to evaluate an immersive virtual reality program designed to support cognitive and emotional well-being in older adults with mild to moderate cognitive impairment. The program uses nature-based environments combined with mindfulness, cognitive stimulation, and breathing techniques. The goal is to determine whether immersive virtual reality can be a safe and effective tool to improve well-being and support active and healthy aging.\n\nThe study will be conducted in two phases. In the first phase, virtual environments will be tested in healthy participants using behavioral and physiological measures. In the second phase, 200 older adults with cognitive impairment from day care centers and residential facilities will participate in a group-based immersive virtual reality intervention consisting of 10 sessions.\n\nResearchers will assess changes in cognitive function, emotional wellbeing, daily functioning, and quality of life before and after the intervention.",[115],"Cognitive Dysfunction",[117,118,119,120,121,122,123],"Immersive Virtual Reality","Cognitive Impairment","Older Adults","Well-being","Quality of Life","Blue and Green Spaces","Cognitive Stimulation","2026-09-01",{"date":126,"type":127},"2026-09-03","ACTUAL",{"date":129,"type":127},"2026-03-31",{"date":131,"type":110},"2026-12",{"name":5,"class":6},1]