[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100649436":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":31,"locations":26,"responsibleParty":37,"collaborators":26,"id":39,"slug":40,"hasResults":41,"nctId":42,"briefTitle":43,"officialTitle":44,"acronym":26,"eligibilityCriteria":45,"healthyVolunteers":41,"sex":46,"minAge":47,"maxAge":26,"enrollmentInfo":48,"targetDuration":26,"studyType":51,"phases":52,"briefSummary":54,"conditions":55,"keywords":26,"overallStatus":58,"whyStopped":26,"lastUpdateSubmitDate":59,"lastUpdatePostDateStruct":60,"startDateStruct":63,"completionDateStruct":65,"leadSponsor":67,"locationsCount":26},{"fullName":5,"class":6},"Shanghai Zhongshan Hospital","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"3D-EIT Visual Biofeedback Group","EXPERIMENTAL","Participants will perform standardized Acapella breathing exercises with real-time 3D-EIT visual biofeedback in addition to routine verbal and demonstration-based instructions. Participants will view their own ventilation images and adjust their breathing to increase dorsal ventilation and\u002For improve ventilation homogeneity.",[13,14],"Device: Acapella Oscillating Positive Expiratory Pressure Breathing Exercise","Device: Real-Time 3D Electrical Impedance Tomography Visual Biofeedback",{"label":16,"type":17,"description":18,"interventionNames":19},"Conventional Acapella Training Group","ACTIVE_COMPARATOR","Participants will perform standardized Acapella breathing exercises under routine verbal and demonstration-based instructions without access to real-time 3D-EIT visual feedback. 3D-EIT data will still be recorded for outcome assessment.",[13],[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","Acapella Oscillating Positive Expiratory Pressure Breathing Exercise","Participants will perform standardized breathing exercises using an Acapella oscillating positive expiratory pressure device. Each session will consist of 3 sets of 8-10 breaths, with 10-15 seconds of rest between breaths and 1-2 minutes of rest between sets. Participants will be instructed to inhale slowly and exhale through the Acapella device. The resistance setting will be predetermined and kept unchanged throughout the session.",[9,16],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Real-Time 3D Electrical Impedance Tomography Visual Biofeedback","Participants in the experimental group will view their own real-time 3D electrical impedance tomography (3D-EIT) ventilation images while performing standardized Acapella breathing exercises. The visual feedback will be used to guide breathing adjustments with the aim of increasing dorsal lung ventilation and\u002For improving ventilation homogeneity. The 3D-EIT system will also record ventilation data for outcome assessment.",[9],[32],{"name":33,"role":34,"phone":35,"phoneExt":26,"email":36},"Yuxian Wang","CONTACT","+86 021 6404 1990","wang.yuxian@zs-hospital.sh.cn",{"type":38,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR","100649436","impact-of-3d-eit-guided-acapella-breathing-training-on-lung-ventilation-distribution-100649436",false,"NCT07733843","Impact of 3D-EIT-Guided Acapella Breathing Training on Lung Ventilation Distribution","Impact of Visualized 3D-EIT-Guided Acapella Breathing Training on Lung Ventilation Distribution: A Prospective Single-Center Randomized Controlled Trial","Inclusion Criteria:\n\n* Age ≥18 years.\n* Adult patients in the stable recovery phase following critical illness, breathing spontaneously, alert, and able to follow instructions (suggested Richmond Agitation-Sedation Scale \\[RASS\\] score of -1 to +1).\n* Hemodynamically stable, with no vasopressor support or only a low and stable dose of vasopressors.\n* Receiving stable low-flow oxygen therapy or equivalent non-escalating respiratory support, without an anticipated need for escalation in the short term.\n* Clinically considered suitable for standardized Acapella breathing exercises.\n* Able and willing to provide written informed consent.\n\nExclusion Criteria:\n\n* Significant hemodynamic instability or clinically significant cardiac arrhythmia.\n* Untreated pneumothorax or active hemoptysis.\n* Severe chest wall skin injury or allergy to electrode materials that prevents application of the electrical impedance tomography electrodes.\n* Significant delirium or inability to understand or follow study instructions.\n* Any other condition that, in the investigator's judgment, makes the participant unsuitable for participation in the study.","ALL","18 Years",{"count":49,"type":50},30,"ESTIMATED","INTERVENTIONAL",[53],"NA","The goal of this randomized clinical trial is to determine whether real-time visual feedback from three-dimensional electrical impedance tomography (3D-EIT) can improve the effects of Acapella breathing exercises in adults recovering from critical illness. 3D-EIT is a noninvasive bedside imaging method that provides real-time information about how ventilation is distributed within the lungs.\n\nParticipants will be randomly assigned to one of two groups. Both groups will perform a standardized Acapella breathing exercise while 3D-EIT data and vital signs are recorded. Participants in the control group will receive routine verbal and demonstration-based breathing instructions without viewing the EIT images. Participants in the intervention group will receive the same instructions and will also view their own real-time 3D-EIT ventilation images. They will use this visual feedback to adjust their breathing with the goal of increasing ventilation in the dorsal regions of the lungs and\u002For achieving a more even distribution of ventilation.\n\nThe main question is whether 3D-EIT-guided visual feedback results in a greater improvement in end-expiratory lung impedance (EELI) after breathing exercise compared with routine instruction alone. The study will also examine changes in regional ventilation distribution, ventilation inhomogeneity, vital signs, breathing discomfort, comfort and tolerance, achievement of the breathing-training target, and adverse events.\n\nApproximately 30 participants will be enrolled and randomly assigned in a 1:1 ratio to the two study groups.",[56,57],"Critical Illness Recovery","Pulmonary Rehabilitation","NOT_YET_RECRUITING","2026-07-25",{"date":61,"type":62},"2026-07-29","ACTUAL",{"date":64,"type":50},"2026-07-31",{"date":66,"type":50},"2027-03-21",{"name":5,"class":6}]