[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100659145":3},{"organization":4,"outcomesModule":7,"designInfo":29,"detailedDescription":38,"studyPopulation":28,"armGroups":39,"interventions":49,"overallOfficials":59,"centralContacts":63,"locations":74,"responsibleParty":93,"collaborators":96,"id":98,"slug":99,"hasResults":100,"nctId":101,"briefTitle":102,"officialTitle":103,"acronym":104,"eligibilityCriteria":105,"healthyVolunteers":100,"sex":106,"minAge":107,"maxAge":108,"enrollmentInfo":109,"targetDuration":28,"studyType":112,"phases":113,"briefSummary":115,"conditions":116,"keywords":119,"overallStatus":125,"whyStopped":28,"lastUpdateSubmitDate":126,"lastUpdatePostDateStruct":127,"startDateStruct":130,"completionDateStruct":132,"leadSponsor":134,"locationsCount":135},{"fullName":5,"class":6},"University of Seville","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":28},[9],{"measure":10,"description":11,"timeFrame":12},"Functional Capacity","Functional capacity will be assessed using the One-Minute Sit-to-Stand Test (1MSTS). Participants will be instructed to stand up and sit down from a standardized chair as many times as possible within one minute. The total number of completed repetitions will be recorded, with higher scores indicating better functional capacity.","Baseline (pre-surgery), 8 weeks (post-intervention), and 12 weeks (4-week follow-up)",[14,18,21,25],{"measure":15,"description":16,"timeFrame":17},"Dyspnea","Dyspnea will be assessed using the Modified Medical Research Council (mMRC) scale. This is a 5-point ordinal scale (0-4) where higher scores indicate greater breathlessness and functional limitation due to dyspnea.","Baseline, 8 weeks, and 12 weeks",{"measure":19,"description":20,"timeFrame":17},"Physical Activity Level","Physical activity will be assessed using the International Physical Activity Questionnaire - Short Form (IPAQ-SF). Results will be expressed in MET-minutes\u002Fweek and categorized into low, moderate, or high physical activity levels according to standardized scoring protocols.",{"measure":22,"description":23,"timeFrame":24},"Postoperative Pulmonary Complications","Postoperative pulmonary complications will be collected from clinical records and defined according to EPCO (European Perioperative Clinical Outcome) criteria. Complications will be recorded from hospital discharge until the end of the intervention and follow-up period.","Post-surgery to 12-week follow-up",{"measure":26,"description":27,"timeFrame":17},"Health-Related Quality of Life","Health-related quality of life will be assessed using the EQ-5D-5L questionnaire, including the descriptive system (five dimensions with five levels each) and the EQ visual analogue scale (EQ-VAS, 0-100). Higher scores indicate better perceived health status.",null,{"allocation":30,"interventionModel":31,"interventionModelDescription":32,"primaryPurpose":33,"observationalModel":28,"timePerspective":28,"maskingInfo":34},"RANDOMIZED","PARALLEL","Participants will be randomly assigned in a 1:1 ratio to one of two parallel study arms. The experimental group will receive usual postoperative care plus an 8-week telerehabilitation program based on therapeutic exercise, whereas the control group will receive usual postoperative care alone. Outcomes will be assessed at baseline, after the intervention period, and following a 4-week follow-up period.","SUPPORTIVE_CARE",{"masking":35,"maskingDescription":28,"whoMasked":36},"SINGLE",[37],"OUTCOMES_ASSESSOR","Lung cancer remains the leading cause of cancer-related mortality worldwide and continues to impose a substantial burden on healthcare systems. Surgical resection is considered the standard treatment for patients with resectable disease and offers the best opportunity for long-term survival. However, despite advances in surgical techniques and perioperative care, recovery following thoracic surgery is frequently characterized by impaired physical function, reduced exercise capacity, dyspnea, decreased physical activity levels, postoperative pulmonary complications, and deterioration in health-related quality of life.\n\nThe physical and functional consequences of lung cancer treatment may persist for months or years after surgery and can negatively affect independence, participation in daily activities, and overall well-being. Postoperative rehabilitation and therapeutic exercise have therefore become important components of comprehensive cancer care. Early physiotherapy interventions aim to prevent postoperative pulmonary complications, facilitate recovery of physical function, reduce symptom burden, and promote a safe return to daily activities. Previous studies have shown that exercise-based rehabilitation following lung resection can improve functional capacity and quality of life while reducing postoperative morbidity.\n\nDespite these recognized benefits, access to structured rehabilitation programs remains limited in many healthcare settings due to geographical, logistical, organizational, and resource-related barriers. This challenge is particularly relevant in publicly funded healthcare systems, where rehabilitation services may not be universally available after hospital discharge. As a result, many patients do not receive adequate follow-up rehabilitation during a critical phase of postoperative recovery.\n\nTelerehabilitation has emerged as a promising alternative model of healthcare delivery that enables rehabilitation services to be provided remotely through digital technologies. This approach has the potential to improve accessibility, continuity of care, adherence to prescribed exercise programs, and patient engagement while reducing travel requirements and healthcare costs. Growing evidence supports the safety, feasibility, and effectiveness of telemedicine and telerehabilitation interventions across a variety of chronic and oncological conditions.\n\nIn patients with lung cancer, recent studies have reported encouraging results regarding the use of mobile applications and remotely supervised rehabilitation programs. These interventions have been associated with improved adherence to treatment, enhanced functional recovery, better pulmonary function, increased physical activity levels, reduced symptom burden, and improvements in quality of life. Furthermore, digital rehabilitation strategies may facilitate long-term monitoring and support during the postoperative period, helping patients maintain active participation in their recovery process.\n\nNevertheless, important knowledge gaps remain. The number of high-quality randomized controlled trials specifically evaluating structured postoperative telerehabilitation programs after lung cancer surgery is still limited. Existing studies have often included small sample sizes, heterogeneous interventions, or mixed cancer populations, making it difficult to establish definitive recommendations regarding the optimal design and clinical effectiveness of telerehabilitation in this population. Additional research is needed to determine whether remotely delivered therapeutic exercise programs can produce clinically meaningful improvements in postoperative recovery and patient-centered outcomes.\n\nThe present randomized controlled trial has been designed to address this evidence gap by evaluating the effectiveness of an eight-week telerehabilitation program based on therapeutic exercise in patients undergoing thoracic surgery for lung cancer. Participants allocated to the intervention group will receive a structured and progressive exercise program delivered through a dedicated telerehabilitation platform, combined with regular online clinical follow-up sessions. The intervention incorporates aerobic exercise, muscle strengthening exercises, respiratory muscle training, individualized progression, and continuous monitoring of adherence and symptoms. Participants assigned to the control group will receive the usual postoperative physiotherapy care routinely provided after thoracic surgery.\n\nThe study will evaluate the impact of the intervention on key dimensions of postoperative recovery, including functional capacity, dyspnea, physical activity levels, postoperative pulmonary complications, and health-related quality of life. Assessments will be performed before surgery, after completion of the intervention period, and following a short-term follow-up period to explore the maintenance of potential benefits.\n\nThe findings of this study may contribute to the development of evidence-based rehabilitation pathways for patients recovering from lung cancer surgery. If effective, this telerehabilitation model could represent an accessible, scalable, and cost-efficient strategy for improving postoperative outcomes and expanding access to rehabilitation services within routine clinical practice.",[40,45],{"label":41,"type":42,"description":28,"interventionNames":43},"Telerehabilitation + Usual Care","ACTIVE_COMPARATOR",[44],"Behavioral: Therapeutic Exercise-Based Telerehabilitation",{"label":46,"type":42,"description":28,"interventionNames":47},"Usual Care",[48],"Other: Usual Postoperative Care",[50,55],{"type":51,"name":52,"description":53,"armGroupLabels":54,"otherNames":28},"BEHAVIORAL","Therapeutic Exercise-Based Telerehabilitation","Participants will receive an 8-week telerehabilitation program delivered through the RehBody platform. The intervention includes 24 supervised therapeutic exercise sessions and 8 online clinical follow-up sessions. Exercise sessions incorporate aerobic training, strength exercises, respiratory muscle training, individualized progression, symptom monitoring, and adherence support. Participants will also receive usual postoperative care.",[41],{"type":6,"name":56,"description":57,"armGroupLabels":58,"otherNames":28},"Usual Postoperative Care","Participants assigned to the control group will receive usual postoperative care routinely provided after thoracic surgery for lung cancer. This includes early mobilization, progressive ambulation according to individual tolerance, deep breathing exercises, active upper-limb and trunk mobility exercises, cough training with wound protection, and discharge recommendations for home-based recovery. No structured telerehabilitation or supervised exercise program will be provided after hospital discharge.",[46],[60],{"name":61,"affiliation":5,"role":62},"María Jesús Casuso Holgado","PRINCIPAL_INVESTIGATOR",[64,70],{"name":65,"role":66,"phone":67,"phoneExt":68,"email":69},"David Ortega Valle, PT, MSc","CONTACT","663616650","+34","davortval@alum.us.es",{"name":71,"role":66,"phone":72,"phoneExt":68,"email":73},"María Jesús Casuso Holgado, PT, PhD","659213135","mcasuso@us.es",[75],{"facility":76,"status":28,"city":77,"state":78,"zip":79,"country":80,"countryCode":81,"cosmosGeoPoint":82,"geoPoint":87,"contacts":88},"Hospital Universitario Virgen Macarena","Seville","Andalusia","41009","Spain","ES",{"type":83,"coordinates":84},"Point",[85,86],-5.97317,37.38283,{"lat":86,"lon":85},[89,90,91],{"name":65,"role":66,"phone":67,"phoneExt":68,"email":69},{"name":71,"role":62,"phone":28,"phoneExt":28,"email":28},{"name":65,"role":92,"phone":28,"phoneExt":28,"email":28},"SUB_INVESTIGATOR",{"type":62,"investigatorFullName":94,"investigatorTitle":95,"investigatorAffiliation":5,"oldNameTitle":28,"oldOrganization":28},"Maria Jesus Casuso-Holgado","Associate Professor",[97],{"name":76,"class":6},"100659145","impact-of-a-telerehabilitation-based-therapeutic-exercise-program-on-postoperative-recovery-in-patients-with-lung-cancer-a-randomized-controlled-trial-100659145",false,"NCT07861282","Impact of a Telerehabilitation-based Therapeutic Exercise Program on Postoperative Recovery in Patients With Lung Cancer: A Randomized Controlled Trial.","Impact of a Therapeutic Exercise Program Delivered Through Telerehabilitation on Postoperative Recovery in Patients Diagnosed With Lung Cancer (TEPUL): A Randomized Controlled Clinical Trial.","TEPUL","Inclusion Criteria:\n\n* Adults aged 18 to 80 years.\n* Histologically confirmed primary lung cancer (stage 0 to IIIB).\n* Patients who have undergone thoracic surgery for lung cancer.\n* Medical clearance to participate in an exercise-based rehabilitation program.\n* Ability to understand and communicate verbally.\n* Access to a smartphone and\u002For computer with internet connection.\n\nExclusion Criteria:\n\n* Any medical condition or comorbidity that contraindicates participation in an exercise program.\n* Current psychiatric disorder that may interfere with study participation.\n* Inability to provide written informed consent.\n* Previous thoracic surgery.\n* History of another malignancy within the past five years.","ALL","18 Years","80 Years",{"count":110,"type":111},56,"ESTIMATED","INTERVENTIONAL",[114],"NA","Lung cancer is one of the leading causes of cancer-related morbidity and mortality worldwide. Thoracic surgery remains the treatment of choice for patients with early-stage disease; however, postoperative recovery is frequently associated with reduced functional capacity, decreased physical activity levels, pulmonary complications, dyspnea, and impaired quality of life. Early physiotherapy interventions are recommended to minimize these adverse outcomes, although access to postoperative rehabilitation services remains limited in many healthcare settings, including the Andalusian Public Health System.\n\nTelerehabilitation has emerged as a promising strategy to improve access to rehabilitation services by delivering therapeutic exercise and clinical follow-up remotely. Previous studies have demonstrated that telerehabilitation is safe, effective, and cost-efficient across different clinical populations. However, evidence regarding its effectiveness in patients recovering from lung cancer surgery remains limited.\n\nThis single-blind randomized controlled trial aims to compare the effects of an eight-week telerehabilitation program based on therapeutic exercise with usual postoperative care in patients with lung cancer undergoing thoracic surgery. Participants allocated to the intervention group will receive 24 therapeutic exercise sessions and 8 online clinical follow-up sessions delivered through the Rehbody platform over an 8-week period. Outcomes will include functional capacity, dyspnea, physical activity level, postoperative pulmonary complications, and health-related quality of life.\n\nThe study is designed to address the following research question: In adults with lung cancer undergoing thoracic surgery (Population), does an eight-week therapeutic exercise-based telerehabilitation program (Intervention), compared with usual postoperative care (Comparison), improve postoperative recovery as measured by functional capacity, dyspnea, physical activity level, postoperative pulmonary complications, and quality of life (Outcomes)?",[117,118],"Lung Neoplasms","Thoracic Surgery Lung",[120,117,121,15,122,123,124],"Thoracic Surgery","Telerehabilitation","Exercise Therapy","Quality of Life","Postoperative Complications","NOT_YET_RECRUITING","2026-09-30",{"date":128,"type":129},"2026-10-06","ACTUAL",{"date":131,"type":111},"2026-10",{"date":133,"type":111},"2028-11",{"name":5,"class":6},1]