[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100653450":3},{"organization":4,"outcomesModule":7,"designInfo":26,"detailedDescription":25,"studyPopulation":29,"armGroups":30,"interventions":25,"overallOfficials":25,"centralContacts":25,"locations":34,"responsibleParty":47,"collaborators":25,"id":51,"slug":52,"hasResults":53,"nctId":54,"briefTitle":55,"officialTitle":55,"acronym":25,"eligibilityCriteria":56,"healthyVolunteers":53,"sex":57,"minAge":58,"maxAge":25,"enrollmentInfo":59,"targetDuration":25,"studyType":62,"phases":25,"briefSummary":63,"conditions":64,"keywords":67,"overallStatus":72,"whyStopped":25,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":82},{"fullName":5,"class":6},"Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":25},[9],{"measure":10,"description":11,"timeFrame":12},"Change in Serum Troponin Concentration From Preoperative Baseline to 24 Hours After Surgery","Postoperative troponin elevation will be assessed by comparing serum troponin levels measured preoperatively and 24 hours after surgery. Its association with intraoperative perfusion variability will be evaluated.","Preoperatively and 24 hours after surgery",[14,18,22],{"measure":15,"description":16,"timeFrame":17},"Association Between Intraoperative Perfusion Index and Postoperative Troponin Elevation","Perfusion Index (PI) will be continuously monitored intraoperatively and recorded at 15-minute intervals. The association between intraoperative PI values and postoperative troponin elevation at 24 hours after surgery will be evaluated.","Intraoperative monitoring from the start to the end of surgery; troponin measured preoperatively and at 24 hours postoperatively",{"measure":19,"description":20,"timeFrame":21},"Association Between Intraoperative Pleth Variability Index and Postoperative Troponin Elevation","Pleth Variability Index (PVI) will be continuously monitored intraoperatively and recorded at 15-minute intervals. The association between intraoperative PVI values and postoperative troponin elevation at 24 hours after surgery will be evaluated.","Intraoperative monitoring from the start to the end of surgery; troponin measured preoperatively and at 24 hours postoperatively.",{"measure":23,"description":24,"timeFrame":21},"Association Between Intraoperative Cerebral Oxygen Saturation and Postoperative Troponin Elevation","Cerebral oxygen saturation measured by near-infrared spectroscopy (NIRS) will be continuously monitored intraoperatively and recorded at 15-minute intervals. The association between intraoperative cerebral oxygen saturation values and postoperative troponin elevation at 24 hours after surgery will be evaluated.",null,{"allocation":25,"interventionModel":25,"interventionModelDescription":25,"primaryPurpose":25,"observationalModel":27,"timePerspective":28,"maskingInfo":25},"COHORT","PROSPECTIVE","Geriatric patients aged 65 years or older undergoing major abdominal oncologic surgery who meet the predefined eligibility criteria and have preoperative and 24-hour postoperative troponin measurements. Intraoperative hemodynamic and perfusion parameters, including PI, PVI, and cerebral oxygen saturation measured by NIRS, will be monitored throughout surgery and recorded at 15-minute intervals.",[31],{"label":32,"type":25,"description":33,"interventionNames":25},"Geriatric Patients Undergoing Major Oncologic Surgery","Geriatric patients undergoing elective major oncolojic surgery will be prospectively observed.Intraoperative hemodynamic and perfusion-related parameters will be recorded, and serum troponin levels will be measured preoperatively and 24 hours after surgery to evaluate the association between intraoperative perfusion variability and postoperative troponin elevation.",[35],{"facility":36,"status":25,"city":37,"state":38,"zip":39,"country":40,"countryCode":25,"cosmosGeoPoint":41,"geoPoint":46,"contacts":25},"Ankara Dr. Abdurrahman Yurtaslan Oncolgy Training and Research Hospital","Yenimahalle","Ankara","06200","Turkey (Türkiye)",{"type":42,"coordinates":43},"Point",[44,45],32.80147,39.97787,{"lat":45,"lon":44},{"type":48,"investigatorFullName":49,"investigatorTitle":50,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Özlem Kapusuz","Principal Investigator","100653450","impact-of-intraoperative-perfusion-variability-on-postoperative-troponin-elevation-in-geriatric-patients-undergoing-major-oncologic-surgery-100653450",false,"NCT07786753","Impact of Intraoperative Perfusion Variability on Postoperative Troponin Elevation in Geriatric Patients Undergoing Major Oncologic Surgery","Inclusion Criteria:\n\n* Age 65 years or older\n* Undergoing major abdominal oncologic surgery\n* Availability of preoperative and 24-hour postoperative troponin measurements\n* Complete intraoperative and postoperative patient monitoring records\n* Provision of written informed consent\n\nExclusion Criteria:\n\n* Age younger than 65 years\n* Absence of preoperative or 24-hour postoperative troponin measurements\n* Incomplete intraoperative or postoperative patient monitoring records\n* Undergoing emergency surgery\n* Advanced heart failure\n* ASA Physical Status IV\n* Pulmonary artery pressure \\>40 mmHg","ALL","65 Years",{"count":60,"type":61},70,"ESTIMATED","OBSERVATIONAL","This prospective observational study aims to evaluate the association between intraoperative perfusion variability and postoperative troponin elevation in geriatric patients undergoing major oncologic surgery. Intraoperative hemodynamic and perfusion-related parameters will be recorded, and postoperative troponin levels will be assessed to investigate whether intraoperative perfusion changes are associated with myocardial injury. Troponin measurements will be obtained preoperatively and at 24 hours after surgery",[65,66],"Postoperative Troponin Elevation","Intraoperative Perfusion",[65,68,69,66,70,71],"Geriatric Patients","Major Oncologic Surgery","Troponin","Hemodynamic Variability","NOT_YET_RECRUITING","2026-09-13",{"date":75,"type":76},"2026-09-16","ACTUAL",{"date":78,"type":61},"2026-09-01",{"date":80,"type":61},"2026-11-02",{"name":5,"class":6},1]