[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100649810":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":24,"centralContacts":25,"locations":31,"responsibleParty":50,"collaborators":24,"id":53,"slug":54,"hasResults":55,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":24,"eligibilityCriteria":59,"healthyVolunteers":55,"sex":60,"minAge":61,"maxAge":62,"enrollmentInfo":63,"targetDuration":24,"studyType":66,"phases":67,"briefSummary":69,"conditions":70,"keywords":24,"overallStatus":34,"whyStopped":24,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":81},{"fullName":5,"class":6},"University of Catania","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"MINST non surgical periodontal treatment","EXPERIMENTAL","Periodontitis patients treated by means of MINST. Patients were treated with non-surgical MINST periodontal treatment in a single session.",[13],"Other: Probing depth reduction",{"label":15,"type":16,"description":17,"interventionNames":18},"Q-SI non surgical periodontal treatment","ACTIVE_COMPARATOR","Periodontitis patients treated by means of Q-SI. Patients were treated with non-surgical quadrantwise periodontal treatment in 4 sessions, 1 session per week.",[13],[20],{"type":6,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"Probing depth reduction","Probing depth reduction in millimetres before and after treatment",[9,15],null,[26],{"name":27,"role":28,"phone":29,"phoneExt":24,"email":30},"Gaetano Isola","CONTACT","0953785652","gaetano.isola@unict.it",[32],{"facility":33,"status":34,"city":35,"state":36,"zip":37,"country":36,"countryCode":38,"cosmosGeoPoint":39,"geoPoint":44,"contacts":45},"AOU Policlinico G. Rodolico","RECRUITING","Catania","Italy","95123","IT",{"type":40,"coordinates":41},"Point",[42,43],15.07041,37.49223,{"lat":43,"lon":42},[46,47],{"name":27,"role":28,"phone":29,"phoneExt":24,"email":30},{"name":48,"role":28,"phone":29,"phoneExt":24,"email":49},"Rosalia Leonardi","rleonardi@unict.it",{"type":51,"investigatorFullName":27,"investigatorTitle":52,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"PRINCIPAL_INVESTIGATOR","Prof.","100649810","impact-of-non-surgical-periodontal-treatment-on-targeted-metabolomics-100649810",false,"NCT07740447","Impact of Non-surgical Periodontal Treatment on Targeted Metabolomics","Effects of Minimally Non-surgical Periodontal Treatment Versus Quadrantwise Subgingival Instrumentations on Targeted Metabolomics in Gingival Crevicular Fluid","Inclusion Criteria:\n\n* Diagnosis of Periodontitis\n\nExclusion Criteria:\n\n* Periodontal treatment during the last 6 months\n* Use of antibiotics, NSAIDs, and immunosuppressants during the last 6 months\n* Pregnancy","ALL","18 Years","70 Years",{"count":64,"type":65},60,"ESTIMATED","INTERVENTIONAL",[68],"NA","A double-blind randomized-controlled clinical trial is conducted in order to evaluate the impact of non-surgical periodontal treatment by means of minimally invasive approach MINST or Q-SI (quadrantwise) approach in subjects with periodontitis on targeted metabolomics in gingival crevicular fluid",[71],"Periodontitis","2026-07-28",{"date":74,"type":75},"2026-07-31","ACTUAL",{"date":77,"type":75},"2026-05-04",{"date":79,"type":65},"2026-12-18",{"name":5,"class":6},1]