[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100649368":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":30,"centralContacts":35,"locations":45,"responsibleParty":71,"collaborators":25,"id":73,"slug":74,"hasResults":75,"nctId":76,"briefTitle":77,"officialTitle":78,"acronym":25,"eligibilityCriteria":79,"healthyVolunteers":80,"sex":81,"minAge":82,"maxAge":83,"enrollmentInfo":84,"targetDuration":25,"studyType":87,"phases":88,"briefSummary":90,"conditions":91,"keywords":96,"overallStatus":105,"whyStopped":25,"lastUpdateSubmitDate":106,"lastUpdatePostDateStruct":107,"startDateStruct":110,"completionDateStruct":112,"leadSponsor":114,"locationsCount":115},{"fullName":5,"class":6},"USDA, Western Human Nutrition Research Center","FED",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Peanut Intervention followed by corn chips Intervention","EXPERIMENTAL","Participants will be asked to consume 42g of peanuts with skin daily for 4 weeks. Following a 4-week washout, the participant will then be asked to consume 45g of corn chips daily for 4 weeks.",[13,14],"Other: Peanuts, roasted, salted with skins","Other: Isocaloric food",{"label":16,"type":10,"description":17,"interventionNames":18},"Corn chip Intervention followed by Peanut Intervention","The participant will be asked to consume 45g of corn chips daily for 4 weeks. Following a 4-week washout, the participant will be then asked to consume 42g of peanuts with skin daily for 4 weeks.",[13,14],[20,26],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"OTHER","Peanuts, roasted, salted with skins","42g roasted salted peanuts with skins consumed daily",[16,9],null,{"type":21,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Isocaloric food","Corn chips (45g)",[16,9],[31],{"name":32,"affiliation":33,"role":34},"Ryan Snodgrass, PhD","United States Department of Agriculture - Western Human Nutrition Research Center","PRINCIPAL_INVESTIGATOR",[36,41],{"name":37,"role":38,"phone":39,"phoneExt":25,"email":40},"Ellen Bonnel, PhD","CONTACT","530-752-4184","elbonnel@ucdavis.edu",{"name":42,"role":38,"phone":43,"phoneExt":25,"email":44},"Ione Summers, BSc","530-754-8544","iosummerssteffes@ucdavis.edu",[46],{"facility":47,"status":25,"city":48,"state":49,"zip":50,"country":51,"countryCode":52,"cosmosGeoPoint":53,"geoPoint":58,"contacts":59},"Western Human Nutrition Research Center","Davis","California","95616","United States","US",{"type":54,"coordinates":55},"Point",[56,57],-121.74052,38.54491,{"lat":57,"lon":56},[60,61,63,64,67,69],{"name":37,"role":38,"phone":39,"phoneExt":25,"email":40},{"name":62,"role":38,"phone":43,"phoneExt":25,"email":44},"Ione Summers, B.S.",{"name":32,"role":34,"phone":25,"phoneExt":25,"email":25},{"name":65,"role":66,"phone":25,"phoneExt":25,"email":25},"Danielle Lemay, PhD","SUB_INVESTIGATOR",{"name":68,"role":66,"phone":25,"phoneExt":25,"email":25},"Mary Kable, PhD",{"name":70,"role":66,"phone":25,"phoneExt":25,"email":25},"Kevin Laugero, PhD",{"type":72,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR","100649368","impact-of-peanut-consumption-on-stress-immune-function-inflammation-and-cardiovascular-health-in-high-stress-individuals-100649368",false,"NCT07735221","Impact of Peanut Consumption on Stress, Immune Function, Inflammation, and Cardiovascular Health in High-Stress Individuals","Effects of Peanut Consumption on Physiological and Psychosocial Stress, Circulating Immune Cell Status, Markers of Inflammation and Cardiovascular Disease Risk, and Gastrointestinal Health in High-Stress Individuals","Inclusion Criteria:\n\n* Males and females\n* 18-65 years old\n* BMI ≥ 18.5 kg\u002Fm2 and ≤ 39.9 kg\u002F m2\n* Recruitment will be based on Perceived Stress Scale - 4 (PSS-4) score\n\nExclusion Criteria:\n\n* Less than 18 and over 65 years old\n* Pregnant or lactating women\n* Adults who rely on prescription medication that may influence study variables, apart from birth control\n* BMI \\\u003C 18.5 kg\u002Fm2 and \\> 39.9 kg\u002Fm2\n* Smokers who currently use tobacco- or marijuana-containing products including e-cigarettes, vape pens, pod mods, tanks, and electronic nicotine delivery devices (ENDS)\n* Habitual consumption of nuts, nut butters, nut powders, nut side dishes, nut bars or other nut products\n* Known food allergies (milk, eggs, fish, shellfish, tree nuts, peanuts, wheat, soybeans, sesame, corn) due to samples not prepared in a hypoallergenic environment\n* Currently living in close contact with individuals who have an allergy to peanuts, in order to avoid exposing these individuals to an allergen\n* Self-reported history of difficulties with blood drawing procedures including prior fainting or dizziness, or veins assessed as not suitable for four separate venipunctures by licensed phlebotomist\n* Diagnosed active chronic diseases for which the individual is currently taking daily medication, including but not limited to:\n\n  * Diabetes mellitus, cardiovascular disease, cancer, gastrointestinal disorders, kidney disease, liver disease, bleeding disorders, asthma, autoimmune disorders, hypertension, osteoporosis\n* Recent minor surgery (within 4 weeks) or major surgery (within 16 weeks)\n* Known gallbladder disease or history of cholecystectomy\n* History of gastrointestinal surgery, including gastric bypass surgery or resection\n* Diagnosis of irritable bowel syndrome\n* Recent antibiotic therapy (within 4 weeks)\n* Recent hospitalization (within 4 weeks)\n* Current participation in another research study\n* Has HIV\u002FAIDS, hepatitis, or another disease that affects the immune system\n* Gives regular blood donations and is unwilling to stop during the study\n* Blood Pressure ≥ 140 mmHg systolic or 90 mmHg diastolic\n* Current diagnoses of an eating disorder (ex. anorexia, bulimia, etc.)\n* High - very high triglyceride levels: ≥ 300 mg\u002FdL\n* Adults who are unable to consent, individuals who are not yet adults (infants, children and teenagers), pregnant women and prisoners will be excluded from participation in the study\n* Participants who are unwilling to collect and transport urine, stool and saliva samples\n* Abnormal hemoglobin and\u002For hematocrit levels\n* Abnormal liver function (defined as liver enzymes that are \\>200% of upper limit (ALT upper limit is 43 U\u002FL or Aspartate transaminase (AST) upper limit is 54 U\u002FL)\n* Unwillingness to discontinue probiotic, prebiotic, fiber, or other supplements (except RDA-level vitamin and mineral supplements) during the study\n* Unwilling to consume study foods\n* Alcohol consumption \\> 20 g\u002Fday",true,"ALL","18 Years","65 Years",{"count":85,"type":86},70,"ESTIMATED","INTERVENTIONAL",[89],"NA","The purpose of this research is to determine whether peanut consumption improves indicators of cardiovascular disease (CVD) risk in human subjects following the consumption of study foods.",[92,93,94,95],"Immune System","Stress","Chronic Stress","Cardiovascular Health",[97,98,99,100,101,102,103,104],"peanut","stress","immune function","cardiovascular health","chronic stress","pss10","inflammation","gut microbiota","NOT_YET_RECRUITING","2026-08-13",{"date":108,"type":109},"2026-08-17","ACTUAL",{"date":111,"type":86},"2026-09",{"date":113,"type":86},"2028-08",{"name":5,"class":6},1]