[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100651696":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":12,"locations":21,"responsibleParty":38,"collaborators":10,"id":42,"slug":43,"hasResults":44,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":48,"eligibilityCriteria":49,"healthyVolunteers":44,"sex":50,"minAge":51,"maxAge":52,"enrollmentInfo":53,"targetDuration":56,"studyType":57,"phases":10,"briefSummary":58,"conditions":59,"keywords":63,"overallStatus":24,"whyStopped":10,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":75},{"fullName":5,"class":6},"Nanjing First Hospital, Nanjing Medical University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":10},"DCB-Treated De Novo Lesion",null,"Patients undergoing drug-coated balloon treatment for de novo coronary lesions",[13,19],{"name":14,"role":15,"phone":16,"phoneExt":17,"email":18},"Fei Ye, MD","CONTACT","18951670287","+86","doctor_ye@126.com",{"name":20,"role":15,"phone":10,"phoneExt":10,"email":10},"Tian-lei Zhang, MD",[22],{"facility":23,"status":24,"city":25,"state":26,"zip":27,"country":28,"countryCode":29,"cosmosGeoPoint":30,"geoPoint":35,"contacts":36},"Nanjing First Hospital","RECRUITING","Nanjing","Jiangsu","210006","China","CN",{"type":31,"coordinates":32},"Point",[33,34],118.77778,32.06167,{"lat":34,"lon":33},[37],{"name":14,"role":15,"phone":16,"phoneExt":17,"email":18},{"type":39,"investigatorFullName":40,"investigatorTitle":41,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Ye-fei","chief physician","100651696","impact-of-procedural-factors-on-drug-coated-balloon-outcomes-in-coronary-artery-disease-100651696",false,"NCT07764094","Impact of Procedural Factors on Drug-Coated Balloon Outcomes in Coronary Artery Disease","Impact of Drug-Coated Balloon Procedural Factors on Angiographic and Clinical Outcomes of Percutaneous Coronary Intervention for De Novo Lesions: A Multicenter, Prospective, Observational Registry","DT","Inclusion Criteria:\n\n1. Age ≥18 years\n2. Stable coronary artery disease or unstable angina\n3. De novo coronary lesion (reference vessel diameter 2.25-4.0 mm; lesion length ≤40 mm)\n4. Planned DCB strategy for PCI\n5. Written informed consent\n\nExclusion Criteria:\n\n1. Acute myocardial infarction within 72 hours\n2. Severe heart failure (NYHA class IV)\n3. Severe hepatic or renal insufficiency\n4. Allergy to drug-coated balloon components or antiplatelet agents, or intolerance to dual antiplatelet therapy\n5. Life expectancy \\\u003C12 months\n6. Pregnancy or breastfeeding\n7. Concurrent participation in another clinical trial\n8. In-stent restenosis\n9. Unsuccessful recanalization of main vessel or side branch chronic total occlusion\n10. Hemodynamic instability","ALL","18 Years","80 Years",{"count":54,"type":55},500,"ESTIMATED","1 Year","OBSERVATIONAL","This registry aimed to investigate drug-coated balloon procedural factors (particularly delivery time and inflation duration) to evaluate the impact on angiographic and clinical outcomes in patients undergoing percutaneous coronary intervention for de novo coronary lesions.",[60,61,62],"PCI","Drug-coated Balloon","Coronary Artery Disease",[64,65],"Percutaneous coronary intervention","Drug coated balloon","2026-08-09",{"date":68,"type":69},"2026-08-13","ACTUAL",{"date":71,"type":55},"2026-09-01",{"date":73,"type":55},"2028-06-30",{"name":5,"class":6},1]